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Journal Highlight: Proteomics applied to transfusion plasma: the beginning of the story

Date: May 20, 2013

Author: spectroscopyNOW

The principles of proteomics analysis and the state of the art applied to plasma analysis are presented, along with the use of proteomics for assessing the impact of storage conditions and pathogen inactivation treatments on transfusion plasma.

Read More thumbnail image: Journal Highlight Proteomics applied to transfusion plasma the beginning of the story

Unlikely partners: IEF coupled to ambient mass spectrometry

Date: May 16, 2013

Author: Steve Down

Isoelectric focusing gel electrophoresis has been coupled directly to mass spectrometry in a proof-of-concept study for the analysis of intact proteins and peptides.

Read More thumbnail image: Unlikely partners IEF coupled to ambient mass spectrometry

Pork processing: Proteins influencing water holding capacity and drip loss

Date: May 1, 2013

Author: Steve Down

The proteome of fresh pork meat has been examined to locate proteins that are involved in the abnormal loss of water and soluble proteins due to limited water holding capacity, which impacts on meat quality.

Read More thumbnail image: Pork processing Proteins influencing water holding capacity and drip loss

Journal Highlight: Effects of acute exercise over heart proteome from monogenic obese (ob/ob) mice

Date: Apr 22, 2013

Author: spectroscopyNOW

To elucidate the effects of acute exercise in heart tissue from obese animals, 12-week-old obese (ob/ob) and non-obese (ob/OB) mice were submitted to a single bout of swimming and had their hearts analyzed by proteomic techniques.

Read More thumbnail image: Journal Highlight Effects of acute exercise over heart proteome from monogenic obese obob mice

Chromosomal proteins: Placental proteome in the C-HPP

Date: Apr 15, 2013

Author: Steve Down

Thousands of human placental proteins have been identified in a genome-wide proteomic analysis as part of the international Chromosome-Centric Human Proteome Project.

Read More thumbnail image: Chromosomal proteins Placental proteome in the C-HPP

A crying shame: Protein panel in tears classifies eye disorders

Date: Apr 1, 2013

Author: Steve Down

The common ocular conditions dry eye and meibomian gland dysfunction can be distinguished from each other using a group of five proteins present in tears, according to Spanish scientists.

Read More thumbnail image: A crying shame Protein panel in tears classifies eye disorders

Journal Highlight: Mass spectrometry-based proteomics: The road to lung cancer biomarker discovery

Date: Mar 24, 2013

Author: spectroscopyNOW

This review describes studies that use mass spectrometry-based proteomics technologies to analyse tumour proteins and peptides which might represent new diagnostic, prognostic and predictive markers for lung cancer.

Read More thumbnail image: Journal Highlight Mass spectrometry-based proteomics The road to lung cancer biomarker discovery

Clearing the airways: Distinguishing smoking-related diseases by NMR

Date: Mar 15, 2013

Author: Steve Down

NMR spectroscopy of the metabolites in exhaled breath condensate can distinguish between airway respiratory diseases induced by smoking, say Italian researchers.

Read More thumbnail image: Clearing the airways Distinguishing smoking-related diseases by NMR

Journal Highlight: Unraveling the different proteomic platforms

Date: Feb 25, 2013

Author: spectroscopyNOW

This review is addressed to scientists working outside the field of proteomics and highlights the latest proteomics strategies, including bottom-up and top-down platforms, qualitative and quantitative methods, and data validation.

Read More thumbnail image: Journal Highlight Unraveling the different proteomic platforms

Alcoholic proteomics: Ethanol effects on proteins in rat liver and serum

Date: Feb 15, 2013

Author: Steve Down

A dual approach to proteomics changes in the rat following a chronic alcohol diet has examined both serum and rat liver, revealing that only one protein was up-regulated in both matrices.

Read More thumbnail image: Alcoholic proteomics Ethanol effects on proteins in rat liver and serum
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