Proteomics & Genomics / Ezine
Journal Highlight: Effects of acute exercise over heart proteome from monogenic obese (ob/ob) mice
Date: Apr 22, 2013
Author: spectroscopyNOW
To elucidate the effects of acute exercise in heart tissue from obese animals, 12-week-old obese (ob/ob) and non-obese (ob/OB) mice were submitted to a single bout of swimming and had their hearts analyzed by proteomic techniques.
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Chromosomal proteins: Placental proteome in the C-HPP
Date: Apr 15, 2013
Author: Steve Down
Thousands of human placental proteins have been identified in a genome-wide proteomic analysis as part of the international Chromosome-Centric Human Proteome Project.
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A crying shame: Protein panel in tears classifies eye disorders
Date: Apr 1, 2013
Author: Steve Down
The common ocular conditions dry eye and meibomian gland dysfunction can be distinguished from each other using a group of five proteins present in tears, according to Spanish scientists.
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Journal Highlight: Mass spectrometry-based proteomics: The road to lung cancer biomarker discovery
Date: Mar 24, 2013
Author: spectroscopyNOW
This review describes studies that use mass spectrometry-based proteomics technologies to analyse tumour proteins and peptides which might represent new diagnostic, prognostic and predictive markers for lung cancer.
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Clearing the airways: Distinguishing smoking-related diseases by NMR
Date: Mar 15, 2013
Author: Steve Down
NMR spectroscopy of the metabolites in exhaled breath condensate can distinguish between airway respiratory diseases induced by smoking, say Italian researchers.
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Journal Highlight: Unraveling the different proteomic platforms
Date: Feb 25, 2013
Author: spectroscopyNOW
This review is addressed to scientists working outside the field of proteomics and highlights the latest proteomics strategies, including bottom-up and top-down platforms, qualitative and quantitative methods, and data validation.
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Alcoholic proteomics: Ethanol effects on proteins in rat liver and serum
Date: Feb 15, 2013
Author: Steve Down
A dual approach to proteomics changes in the rat following a chronic alcohol diet has examined both serum and rat liver, revealing that only one protein was up-regulated in both matrices.
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No slipping up: Banana proteome unpeeled using peptide libraries
Date: Feb 1, 2013
Author: Steve Down
An in-depth proteome study of banana fruit using combinatorial peptide ligand libraries to isolate the proteins from the sugar-rich pulp has identified more than 1100 proteins.
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Journal Highlight: Update on the proteomics of major arthropod vectors of human and animal pathogens
Date: Jan 21, 2013
Author: spectroscopyNOW
This review describes the proteomic approaches that have been used to investigate diverse biological questions about arthropod vectors, including the interplay between vectors and pathogens.
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A menace to mussels: Illicit drugs in waterways induce oxidative stress
Date: Jan 15, 2013
Author: Steve Down
The cocaine metabolite benzoylecgonine causes oxidative stress in freshwater mussels by inducing redox modifications in proteins, some of which are associated with glucose metabolism and cytoskeletal processes.
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