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Graphene oxide nanomaterials: Toxicity mechanisms

Date: Jul 1, 2018

Author: Steve Down

Typical environmental levels of graphene oxide nanoparticles modify the abundances of nearly 250 proteins in zebrafish larvae, tested as a model aquatic species, and bring about malformations and increased mortality, a new proteomics study has revealed.

Read More thumbnail image: Graphene oxide nanomaterials Toxicity mechanisms

Journal Highlight: Revealing the inhibitory effect of ginseng on mitochondrial respiration through synaptosomal proteomics

Date: Jun 25, 2018

Author: spectroscopyNOW

A proteomics study of the synaptosomes of rats treated with ginseng has shown that it can regulate the function of mitochondria and alter the energy metabolism of cells, which may be useful for the treatment of central nervous disorders.

Read More thumbnail image: Journal Highlight Revealing the inhibitory effect of ginseng on mitochondrial respiration through synaptosomal proteomics

Asthma control: Protein biomarkers

Date: Jun 15, 2018

Author: Steve Down

A proteomics study has identified a link between the levels of proteins in the serum and sputum of asthmatics for whom the disease is poorly controlled, providing early indications when further clinical intervention is needed to give a better outcome.

Read More thumbnail image: Asthma control Protein biomarkers

Nicotine proteome effects: Tissue-specific alterations

Date: Jun 1, 2018

Author: Steve Down

US scientists have found that up to 126 proteins in seven tissue types were affected by oral exposure of mice to nicotine, sending warning signals to consumers who smoke electronic cigarettes under the misapprehension that they are safe.

Read More thumbnail image: Nicotine proteome effects Tissue-specific alterations

Journal Highlight: Proteomic analysis of exosomes and Its application in HIV‐1 infection

Date: May 21, 2018

Author: spectroscopyNOW

This review focuses on exosome isolation and purification methods and their implications in HIV‐1 studies as well as the roles of proteomic techniques in defining exosomal contents and the research and clinical applications of proteomics and exosome in HIV‐1 biology.

Read More thumbnail image: Journal Highlight Proteomic analysis of exosomes and Its application in HIV1 infection

Sample preparation in proteomics: Method bias

Date: May 15, 2018

Author: Steve Down

A comparison of four commonly used proteomics sample preparation methods for head and neck tissues has revealed that there is no universal method, each having their own deficiencies and advantages.

Read More thumbnail image: Sample preparation in proteomics Method bias

Postmortem interval: Forensic proteomic pointers

Date: May 1, 2018

Author: Steve Down

A proteomics study of decaying bones has thrown up a number of proteins that might prove to be valuable markers of the skeletal postmortem interval as an aid to forensic scientists.

Read More thumbnail image: Postmortem interval Forensic proteomic pointers

Journal Highlight: Changes in the proteome of the problem weed blackgrass correlating with multiple herbicide resistance

Date: Apr 23, 2018

Author: spectroscopyNOW

The evolution of multiple herbicide resistance in populations of the weed blackgrass (Alopecurus myosuroides) has been investigated using a combination of transcriptomics and proteomics.

Read More thumbnail image: Journal Highlight Changes in the proteome of the problem weed blackgrass correlating with multiple herbicide resistance

Anton Checkov: Cause of death questioned

Date: Apr 15, 2018

Author: Steve Down

Proteome analysis of brown stains on archived personal items of Anton Checkov has yielded proteins related to Mycobacterium tuberculosis, confirming that he had tuberculosis at time of death, but another protein suggests that there may have been a different cause of death.

Read More thumbnail image: Anton Checkov Cause of death questioned

Asthma at work: Proteomics search for biomarkers

Date: Apr 1, 2018

Author: Steve Down

Nasal protein profiling has been used to measure the responses of people exposed to airborne allergens like isocyanates and welding fumes, leading to several candidate biomarkers for work-related asthma.

Read More thumbnail image: Asthma at work Proteomics search for biomarkers
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