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Asthma at work: Proteomics search for biomarkers

Date: Apr 1, 2018

Author: Steve Down

Nasal protein profiling has been used to measure the responses of people exposed to airborne allergens like isocyanates and welding fumes, leading to several candidate biomarkers for work-related asthma.

Read More thumbnail image: Asthma at work Proteomics search for biomarkers

Journal Highlight: Expression of CPPED1 in human trophoblasts is associated with timing of term birth

Date: Mar 26, 2018

Author: spectroscopyNOW

Proteomic analyses of full‐term placentas from uncomplicated pregnancies have been carried out to identify protein signatures associated with the onset of spontaneous delivery, implicating the involvement of CPPED1.

Read More thumbnail image: Journal Highlight Expression of CPPED1 in human trophoblasts is associated with timing of term birth

Mortality biomarkers: Peptides and proteins

Date: Mar 15, 2018

Author: Steve Down

A large-scale proteomics study on older men has identified a number of peptides and proteins that are associated with five-year mortality, most of them arising from non-cancer deaths and implicating a number of biological pathways, especially inflammation.

Read More thumbnail image: Mortality biomarkers Peptides and proteins

Breast cancer in young women: Biomarkers from breast milk

Date: Mar 1, 2018

Author: Steve Down

A preliminary proteomics study of breast milk in younger women collected within two years of them being diagnosed with breast cancer has revealed a number of dysregulated proteins as potential candidates for early detection of the disease.

Read More thumbnail image: Breast cancer in young women Biomarkers from breast milk

Journal Highlight: The human protein atlas: A spatial map of the human proteome

Date: Feb 19, 2018

Author: spectroscopyNOW

The Human Protein Atlas database functions and the ways that users can utilize them for their own research have been comprehensively described, along with the future path of spatial proteomics.

Read More thumbnail image: Journal Highlight The human protein atlas A spatial map of the human proteome

Canine saliva: Inter-breed proteomics

Date: Feb 15, 2018

Author: Steve Down

The proteome of dog saliva differs between breeds and between individual animals of the same breed, say scientists in the UK, who compared differently sized breeds for the first time.

Read More thumbnail image: Canine saliva Inter-breed proteomics

Bioactive peptides from cyanobacteria: In silico prediction

Date: Feb 1, 2018

Author: Steve Down

A proteomics approach employing in silico digestion has been proposed as an alternative way to identify bioactive peptides in aquatic species, exemplified with the edible cyanobacterium Arthrospira platensis.

Read More thumbnail image: Bioactive peptides from cyanobacteria In silico prediction

Journal Highlight: Multiplex quantitative SILAC for analysis of archaeal proteomes: a case study of oxidative stress responses

Date: Jan 22, 2018

Author: spectroscopyNOW

SILAC has been used for the quantitative comparison of archaeal proteomes using Haloferax volcanii as a model to demonstrate its value as a method that holds promise for unravelling gene function.

Read More thumbnail image: Journal Highlight Multiplex quantitative SILAC for analysis of archaeal proteomes a case study of oxidative stress responses

Oral squamous cell carcinoma: Dual protein biomarkers

Date: Jan 15, 2018

Author: Steve Down

A combination of two proteins found in saliva can predict oral squamous cell carcinoma and are unaffected by the risk factors human papillomavirus and Epstein-Barr virus, leading to the possibility of a clinical test for the cancer.

Read More thumbnail image: Oral squamous cell carcinoma Dual protein biomarkers

Heart failure: HDL protein signals

Date: Jan 3, 2018

Author: Steve Down

The proteome of high-density lipoprotein is different for survivors of heart failure and those who died, say an international team of researchers who found that a group of 12 proteins gave strong predictive capabilities.

Read More thumbnail image: Heart failure HDL protein signals
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