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Journal Highlight: Platelet proteomics

Date: Mar 26, 2012

Author:

The aim of this review is to describe recent improvements in platelet proteome studies in normal and pathological conditions, and to depict the main pitfalls associated with platelet proteomics.

Read More thumbnail image: Journal Highlight Platelet proteomics

Climate change consequences: Excess ozone causes major changes in the redox proteome of soybean plants

Date: Mar 15, 2012

Author: Steve Down

Long-term exposure to elevated levels of ozone in the field changes the proteome of soybean plants, specifically modifying many redox proteins. The results may help to understand why the yields of soybean crops are strongly decreased under high ozone atmospheric conditions and lead to new ozone-resistant bioengineered varieties.

Read More thumbnail image: Climate change consequences Excess ozone causes major changes in the redox proteome of soybean plants

Ahead of the game: Proteomics studies of keratins in hair find broken proteins

Date: Mar 1, 2012

Author: Steve Down

A comprehensive proteomics study of the proteins in human hair by two complementary approaches has provided a broad picture of the keratins and keratin-associated proteins and also revealed a set of broken keratins.

Read More thumbnail image: Ahead of the game Proteomics studies of keratins in hair find broken proteins

Journal Highlight: Analysis of proteome and frost tolerance in chromosome 5A and 5B reciprocal substitution lines between two winter wheats during long-term cold acclimation

Date: Feb 27, 2012

Author:

The dynamics of cold tolerance and crown proteome composition have been analysed in a set of two winter wheat cultivars Mironovskaya 808 and Bezostaya 1 and four reciprocal substitution lines with interchanged chromosomes 5A and 5B during a long-term cold-acclimation treatment.

Read More thumbnail image: Journal Highlight Analysis of proteome and frost tolerance in chromosome 5A and 5B reciprocal substitution lines between two winter wheats during long-term cold acclimation

Prostate cancer proteomic test: Use of biomarker panel before biopsy improves diagnoses and saves money

Date: Feb 15, 2012

Author: Steve Down

A diagnostic test for prostate cancer based on the urinary proteome that was devised in 2008 has been applied in the clinical setting in Germany, providing a cost effective confirmation for patients who have tested positive for prostate-specific antigen and avoiding unnecessary biopsies.

Read More thumbnail image: Prostate cancer proteomic test Use of biomarker panel before biopsy improves diagnoses and saves money

Bloody battle of the sexes: Male and female plasma have different protein profiles

Date: Feb 1, 2012

Author: Steve Down

A comparative study of the protein contents in male and female human plasma has revealed some important differences which could be exploited to prevent the occurrence of transfusion-related acute lung injury which can occur following blood transfusion.

Read More thumbnail image: Bloody battle of the sexes Male and female plasma have different protein profiles

Journal Highlight: Proteomics applied to exercise physiology: A cutting-edge technology

Date: Jan 30, 2012

Author:

This review gives an overview of the directions in which exercise-proteome research is moving and examines the main tools that can be used as a novel strategy in exercise physiology investigation.

Read More thumbnail image: Journal Highlight Proteomics applied to exercise physiology A cutting-edge technology

Improving bioimplants: Identifying proteins on modified titanium surfaces

Date: Jan 16, 2012

Author: Steve Down

Proteins adsorbed onto the surfaces of titanium-based biomaterials that are used as implants and artificial joints have been identified by a proteomics technique which could lead to the development of novel materials with improved bioreactivity.

Read More thumbnail image: Improving bioimplants Identifying proteins on modified titanium surfaces

The big picture: Ancient proteins identified in preserved woolly mammoth bone

Date: Jan 5, 2012

Author: Steve Down

A record number of ancient proteins have been isolated and identified from the femur of a 43,000 year-old woolly mammoth that had been preserved in permafrost, using specially developed techniques to minimise contamination along with high-resolution mass spectrometry.

Read More thumbnail image: The big picture Ancient proteins identified in preserved woolly mammoth bone

Journal Highlight: Mass spectrometry-based proteomics approaches applied in cataract research

Date: Dec 15, 2011

Author:

New mass spectrometry-based approaches that are being applied to lens research were highlighted and the future direction of proteomics cataract research was outlined. Mass spectrometry hold great promise to determine which crystallin post-translational modifications lead to a cataract.

Read More thumbnail image: Journal Highlight Mass spectrometry-based proteomics approaches applied in cataract research
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