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Radical problems: Cigarette smoke attacks proteins in oral tissue

Date: May 15, 2012

Author: Steve Down

The reactive aldehydes present in cigarette smoke have a rapid and toxic effect on human oral fibroblasts, oxidising key proteins and reducing their cellular levels, according to a transatlantic study.

Read More thumbnail image: Radical problems Cigarette smoke attacks proteins in oral tissue

Storm in a teacup: Iron levels unchanged but saliva proteome modified after drinking green tea

Date: May 1, 2012

Author: Steve Down

The salivary proteome of rats is modified when green tea is added to their diet, according to researchers in the USA, but the levels of iron in their blood remain unaffected, clarifying this controversial issue.

Read More thumbnail image: Storm in a teacup Iron levels unchanged but saliva proteome modified after drinking green tea

Journal Highlight: Proteomics: present and future in fish, shellfish and seafood

Date: Apr 23, 2012

Author:

A brief overview of current classical proteomics methodology (electrophoresis and mass spectrometry) is presented and focused in the context of applications beneficial to the field of fish, shellfish and seafood/seafood products.

Read More thumbnail image: Journal Highlight Proteomics present and future in fish shellfish and seafood

Seafood spoilers: Streptococcal bacteria in vacuum-packed seafood product isolated and characterised

Date: Apr 15, 2012

Author: Steve Down

A pathogen that causes streptococcosis in fish has been isolated from a spoiled sample of refrigerated, vacuum-packed seafood and characterised by genotyping and proteomic analysis. The mass spectrum of its soluble proteins displays several peaks that are unique to this species and will allow its rapid identification in food products.

Read More thumbnail image: Seafood spoilers Streptococcal bacteria in vacuum-packed seafood product isolated and characterised

Cancer classification: MALDI imaging distinguishes different types of cancer

Date: Apr 1, 2012

Author: Steve Down

Six common types of tumour have been differentiated by mass spectrometry in a proof-of-principle proteomics study by European scientists, which could lead to a personalised treatment regime for cancer sufferers.

Read More thumbnail image: Cancer classification MALDI imaging distinguishes different types of cancer

Journal Highlight: Platelet proteomics

Date: Mar 26, 2012

Author:

The aim of this review is to describe recent improvements in platelet proteome studies in normal and pathological conditions, and to depict the main pitfalls associated with platelet proteomics.

Read More thumbnail image: Journal Highlight Platelet proteomics

Climate change consequences: Excess ozone causes major changes in the redox proteome of soybean plants

Date: Mar 15, 2012

Author: Steve Down

Long-term exposure to elevated levels of ozone in the field changes the proteome of soybean plants, specifically modifying many redox proteins. The results may help to understand why the yields of soybean crops are strongly decreased under high ozone atmospheric conditions and lead to new ozone-resistant bioengineered varieties.

Read More thumbnail image: Climate change consequences Excess ozone causes major changes in the redox proteome of soybean plants

Ahead of the game: Proteomics studies of keratins in hair find broken proteins

Date: Mar 1, 2012

Author: Steve Down

A comprehensive proteomics study of the proteins in human hair by two complementary approaches has provided a broad picture of the keratins and keratin-associated proteins and also revealed a set of broken keratins.

Read More thumbnail image: Ahead of the game Proteomics studies of keratins in hair find broken proteins

Journal Highlight: Analysis of proteome and frost tolerance in chromosome 5A and 5B reciprocal substitution lines between two winter wheats during long-term cold acclimation

Date: Feb 27, 2012

Author:

The dynamics of cold tolerance and crown proteome composition have been analysed in a set of two winter wheat cultivars Mironovskaya 808 and Bezostaya 1 and four reciprocal substitution lines with interchanged chromosomes 5A and 5B during a long-term cold-acclimation treatment.

Read More thumbnail image: Journal Highlight Analysis of proteome and frost tolerance in chromosome 5A and 5B reciprocal substitution lines between two winter wheats during long-term cold acclimation

Prostate cancer proteomic test: Use of biomarker panel before biopsy improves diagnoses and saves money

Date: Feb 15, 2012

Author: Steve Down

A diagnostic test for prostate cancer based on the urinary proteome that was devised in 2008 has been applied in the clinical setting in Germany, providing a cost effective confirmation for patients who have tested positive for prostate-specific antigen and avoiding unnecessary biopsies.

Read More thumbnail image: Prostate cancer proteomic test Use of biomarker panel before biopsy improves diagnoses and saves money
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