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Bioactive peptides from cyanobacteria: In silico prediction

Date: Feb 1, 2018

Author: Steve Down

A proteomics approach employing in silico digestion has been proposed as an alternative way to identify bioactive peptides in aquatic species, exemplified with the edible cyanobacterium Arthrospira platensis.

Read More thumbnail image: Bioactive peptides from cyanobacteria In silico prediction

Journal Highlight: Multiplex quantitative SILAC for analysis of archaeal proteomes: a case study of oxidative stress responses

Date: Jan 22, 2018

Author: spectroscopyNOW

SILAC has been used for the quantitative comparison of archaeal proteomes using Haloferax volcanii as a model to demonstrate its value as a method that holds promise for unravelling gene function.

Read More thumbnail image: Journal Highlight Multiplex quantitative SILAC for analysis of archaeal proteomes a case study of oxidative stress responses

Oral squamous cell carcinoma: Dual protein biomarkers

Date: Jan 15, 2018

Author: Steve Down

A combination of two proteins found in saliva can predict oral squamous cell carcinoma and are unaffected by the risk factors human papillomavirus and Epstein-Barr virus, leading to the possibility of a clinical test for the cancer.

Read More thumbnail image: Oral squamous cell carcinoma Dual protein biomarkers

Heart failure: HDL protein signals

Date: Jan 3, 2018

Author: Steve Down

The proteome of high-density lipoprotein is different for survivors of heart failure and those who died, say an international team of researchers who found that a group of 12 proteins gave strong predictive capabilities.

Read More thumbnail image: Heart failure HDL protein signals

Journal Highlight: Polymorphism-aware protein databases – a prerequisite for an unbiased proteomic analysis of natural populations

Date: Dec 18, 2017

Author: spectroscopyNOW

Transcriptomic and proteomic data of two Drosophila melanogaster genotypes have been used to show the importance of polymorphism in protein databases, especially for the analysis of pooled individuals and the comparison of population samples.

Read More thumbnail image: Journal Highlight Polymorphism-aware protein databases  a prerequisite for an unbiased proteomic analysis of natural populations

Amyloidosis classification: MALDI mass spectrometric imaging

Date: Dec 15, 2017

Author: Steve Down

Scientists in Germany have used mass spectrometry imaging coupled with ion mobility separation to identify amyloid peptides in a proof-of-concept study that will allow different types of amyloidosis to be classified.

Read More thumbnail image: Amyloidosis classification MALDI mass spectrometric imaging

Monitoring bone fracture healing: Protein signals

Date: Dec 1, 2017

Author: Steve Down

Scientists in the USA have uncovered a suite of proteins in serum that might be able to follow the progression of fracture healing and lead to the development of treatments to accelerate the process.

Read More thumbnail image: Monitoring bone fracture healing Protein signals

Journal Highlight: Endocrine imbalance associated with proteome changes in diabetes

Date: Nov 20, 2017

Author: spectroscopyNOW

The cellular signaling and metabolic events that occur in the development of diabetes mellitus have been reviewed along with current and future research methods involving mitochondria.

Read More thumbnail image: Journal Highlight Endocrine imbalance associated with proteome changes in diabetes

Coffee break: Protein alterations after drinking

Date: Nov 15, 2017

Author: Steve Down

A proteomics study of coffee drinkers in Sweden has uncovered inverse associations with two proteins that have been linked to appetite suppression and a number of diseases, including respiratory disorders, Alzheimer's disease and cancer.

Read More thumbnail image: Coffee break Protein alterations after drinking

E-Cigarettes: As dangerous as cigarettes?

Date: Nov 1, 2017

Author: Steve Down

The safety of e-cigarettes has been thrown into doubt following new research which revealed that it induces high levels of proteins in the lungs that are linked with cystic fibrosis, COPD and bronchitis.

Read More thumbnail image: E-Cigarettes As dangerous as cigarettes
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