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Red propolis: Anticancer mechanism probed

Date: Sep 15, 2016

Author: Steve Down

The mechanism by which red propolis acts as an anticancer agent can be clarified by the identification of proteins that are differentially expressed in a cancer cell line, say Brazilian researchers.

Read More thumbnail image: Red propolis Anticancer mechanism probed

Growth hormone testing: Gene and protein markers

Date: Sep 6, 2016

Author: Steve Down

Two genes and a protein that appear in blood following consumption of human growth hormone have been proposed as biomarkers of abuse for sports drug testing programmes, offering better sensitivity than insulin-like growth factor-1.

Read More thumbnail image: Growth hormone testing Gene and protein markers

Journal Highlight: Multiomics approach to identify novel biomarkers for dilated cardiomyopathy: Proteome and transcriptome analyses of 4C30 dilated cardiomyopathy mouse model

Date: Aug 22, 2016

Author: spectroscopyNOW

A proteome and transcriptome analysis of the left ventricle of 4C30 dilated cardiomyopathy model mice was found to be a promising approach for the discovery of new biomarkers.

Read More thumbnail image: Journal Highlight Multiomics approach to identify novel biomarkers for dilated cardiomyopathy Proteome and transcriptome analyses of 4C30 dilated cardiomyopathy mouse model

5000 Yeast proteins measured: Cultures with ten carbon sources compared by multiplexed MS

Date: Aug 17, 2016

Author: Steve Down

A modified mass spectrometric protocol with tandem mass tagging has been used to compare protein abundances in yeast cultures grown on ten different carbon sources, providing data for more than 5000 proteins.

Read More thumbnail image: 5000 Yeast proteins measured Cultures with ten carbon sources compared by multiplexed MS

Autoantibody as prostate cancer marker: Enhanced predictive ability in combination with PSA

Date: Aug 3, 2016

Author: Steve Down

A serological proteome analysis of European-African and African-American men has identified one particular natural antibody as a candidate biomarker for prostate cancer that gives high specificity when combined with the conventional PSA test.

Read More thumbnail image: Autoantibody as prostate cancer marker Enhanced predictive ability in combination with PSA

Journal Highlight: Proteome rearrangements after auditory learning: high-resolution profiling of synapse-enriched protein fractions from mouse brain

Date: Jul 25, 2016

Author: spectroscopyNOW

A label-free quantification approach was utilized to identify regulated synaptic junctional proteins and phosphoproteins in the auditory cortex, frontal cortex, hippocampus, and striatum of mice 24 h after an auditory learning experiment.

Read More thumbnail image: Journal Highlight Proteome rearrangements after auditory learning high-resolution profiling of synapse-enriched protein fractions from mouse brain

Fingermark proteomics: Blood proteins by mass spec imaging

Date: Jul 19, 2016

Author: Steve Down

The proteins in blood that are present on a human fingermark can be identified by a mass spectrometric imaging technique that preserves the integrity of the ridge patterns so that the biometric information can also be extracted.

Read More thumbnail image: Fingermark proteomics Blood proteins by mass spec imaging

Gestational diabetes: Biomarkers of childhood obesity

Date: Jul 14, 2016

Author: Steve Down

Scientists in China have identified proteins in pregnant women who have gestational diabetes, a temporary intolerance to glucose, which might act as biomarkers for childhood obesity.

Read More thumbnail image: Gestational diabetes Biomarkers of childhood obesity

Journal Highlight: Quantitative analysis of oyster larval proteome provides new insights into the effects of multiple climate change stressors

Date: Jun 20, 2016

Author: spectroscopyNOW

To predict how oyster larvae might be affected in a future ocean affected by climate change, changes in the proteome of metamorphosing larvae have been studied under multiple stressors.

Read More thumbnail image: Journal Highlight Quantitative analysis of oyster larval proteome provides new insights into the effects of multiple climate change stressors

Deep vein thrombosis and pulmonary embolism: Urinary peptide signs

Date: Jun 16, 2016

Author: Steve Down

There are a number of small peptides in urine that can signal the onset of deep vein thrombosis and pulmonary embolism, say a team of researchers, who hope that their findings will lead to a clinical test for the conditions.

Read More thumbnail image: Deep vein thrombosis and pulmonary embolism Urinary peptide signs
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