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Journal Highlight: Proteome rearrangements after auditory learning: high-resolution profiling of synapse-enriched protein fractions from mouse brain

Date: Jul 25, 2016

Author: spectroscopyNOW

A label-free quantification approach was utilized to identify regulated synaptic junctional proteins and phosphoproteins in the auditory cortex, frontal cortex, hippocampus, and striatum of mice 24 h after an auditory learning experiment.

Read More thumbnail image: Journal Highlight Proteome rearrangements after auditory learning high-resolution profiling of synapse-enriched protein fractions from mouse brain

Fingermark proteomics: Blood proteins by mass spec imaging

Date: Jul 19, 2016

Author: Steve Down

The proteins in blood that are present on a human fingermark can be identified by a mass spectrometric imaging technique that preserves the integrity of the ridge patterns so that the biometric information can also be extracted.

Read More thumbnail image: Fingermark proteomics Blood proteins by mass spec imaging

Gestational diabetes: Biomarkers of childhood obesity

Date: Jul 14, 2016

Author: Steve Down

Scientists in China have identified proteins in pregnant women who have gestational diabetes, a temporary intolerance to glucose, which might act as biomarkers for childhood obesity.

Read More thumbnail image: Gestational diabetes Biomarkers of childhood obesity

Journal Highlight: Quantitative analysis of oyster larval proteome provides new insights into the effects of multiple climate change stressors

Date: Jun 20, 2016

Author: spectroscopyNOW

To predict how oyster larvae might be affected in a future ocean affected by climate change, changes in the proteome of metamorphosing larvae have been studied under multiple stressors.

Read More thumbnail image: Journal Highlight Quantitative analysis of oyster larval proteome provides new insights into the effects of multiple climate change stressors

Deep vein thrombosis and pulmonary embolism: Urinary peptide signs

Date: Jun 16, 2016

Author: Steve Down

There are a number of small peptides in urine that can signal the onset of deep vein thrombosis and pulmonary embolism, say a team of researchers, who hope that their findings will lead to a clinical test for the conditions.

Read More thumbnail image: Deep vein thrombosis and pulmonary embolism Urinary peptide signs

Protein imaging: The power of MALDI

Date: Jun 2, 2016

Author: Steve Down

The power of two different MALDI mass spectrometric techniques for visualising proteins in tissue segments has been demonstrated by US scientists who exploited high-speed scanning and improved spatial resolution capabilities.

Read More thumbnail image: Protein imaging The power of MALDI

Journal Highlight: Defining the proteome of human iris, ciliary body, retinal pigment epithelium, and choroid

Date: May 23, 2016

Author: spectroscopyNOW

The mass spectrometric proteome of the human iris, ciliary body, and retinal pigment epithelium/choroid has been determined and the data deposited in the ProteomeXchange Consortium

Read More thumbnail image: Journal Highlight Defining the proteome of human iris ciliary body retinal pigment epithelium and choroid

Decompression sickness: Protein biomarkers

Date: May 15, 2016

Author: Steve Down

The onset of decompression sickness in rats leads to a change in the proteome, highlighting proteins which could act as biomarkers of the condition as well as shedding light on the physiological mechanism at play.

Read More thumbnail image: Decompression sickness Protein biomarkers

Dioxin exposure: Human protein biomarkers of TCDD

Date: May 1, 2016

Author: Steve Down

Scientists in the Republic of Korea have identified a number of proteins in human hepatocyte cells that are affected by low doses of 2,3,7,8-tetrachloro-p-dioxin and could act as toxicological biomarkers. Some of them were subsequently found in the blood of exposed incineration workers.

Read More thumbnail image: Dioxin exposure Human protein biomarkers of TCDD

Journal Highlight: Functional proteomics within the genus Lactobacillus

Date: Apr 25, 2016

Author: spectroscopyNOW

This review focuses on the novel and comprehensive knowledge of functional proteomics and metaproteomics of Lactobacillus species, providing a large list of proteomic case studies to illustrate the adaptability of the main metabolic pathways to various life conditions.

Read More thumbnail image: Journal Highlight Functional proteomics within the genus Lactobacillus
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