Proteomics & Genomics / Ezine
Radical problems: Cigarette smoke attacks proteins in oral tissue
Date: May 15, 2012
Author: Steve Down
The reactive aldehydes present in cigarette smoke have a rapid and toxic effect on human oral fibroblasts, oxidising key proteins and reducing their cellular levels, according to a transatlantic study.
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Storm in a teacup: Iron levels unchanged but saliva proteome modified after drinking green tea
Date: May 1, 2012
Author: Steve Down
The salivary proteome of rats is modified when green tea is added to their diet, according to researchers in the USA, but the levels of iron in their blood remain unaffected, clarifying this controversial issue.
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Journal Highlight: Proteomics: present and future in fish, shellfish and seafood
Date: Apr 23, 2012
Author:
A brief overview of current classical proteomics methodology (electrophoresis and mass spectrometry) is presented and focused in the context of applications beneficial to the field of fish, shellfish and seafood/seafood products.
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Seafood spoilers: Streptococcal bacteria in vacuum-packed seafood product isolated and characterised
Date: Apr 15, 2012
Author: Steve Down
A pathogen that causes streptococcosis in fish has been isolated from a spoiled sample of refrigerated, vacuum-packed seafood and characterised by genotyping and proteomic analysis. The mass spectrum of its soluble proteins displays several peaks that are unique to this species and will allow its rapid identification in food products.
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Cancer classification: MALDI imaging distinguishes different types of cancer
Date: Apr 1, 2012
Author: Steve Down
Six common types of tumour have been differentiated by mass spectrometry in a proof-of-principle proteomics study by European scientists, which could lead to a personalised treatment regime for cancer sufferers.
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Journal Highlight: Platelet proteomics
Date: Mar 26, 2012
Author:
The aim of this review is to describe recent improvements in platelet proteome studies in normal and pathological conditions, and to depict the main pitfalls associated with platelet proteomics.
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Climate change consequences: Excess ozone causes major changes in the redox proteome of soybean plants
Date: Mar 15, 2012
Author: Steve Down
Long-term exposure to elevated levels of ozone in the field changes the proteome of soybean plants, specifically modifying many redox proteins. The results may help to understand why the yields of soybean crops are strongly decreased under high ozone atmospheric conditions and lead to new ozone-resistant bioengineered varieties.
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Ahead of the game: Proteomics studies of keratins in hair find broken proteins
Date: Mar 1, 2012
Author: Steve Down
A comprehensive proteomics study of the proteins in human hair by two complementary approaches has provided a broad picture of the keratins and keratin-associated proteins and also revealed a set of broken keratins.
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Journal Highlight: Analysis of proteome and frost tolerance in chromosome 5A and 5B reciprocal substitution lines between two winter wheats during long-term cold acclimation
Date: Feb 27, 2012
Author:
The dynamics of cold tolerance and crown proteome composition have been analysed in a set of two winter wheat cultivars Mironovskaya 808 and Bezostaya 1 and four reciprocal substitution lines with interchanged chromosomes 5A and 5B during a long-term cold-acclimation treatment.
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Prostate cancer proteomic test: Use of biomarker panel before biopsy improves diagnoses and saves money
Date: Feb 15, 2012
Author: Steve Down
A diagnostic test for prostate cancer based on the urinary proteome that was devised in 2008 has been applied in the clinical setting in Germany, providing a cost effective confirmation for patients who have tested positive for prostate-specific antigen and avoiding unnecessary biopsies.
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