Proteomics & Genomics / Ezine
Ahead of the game: Proteomics studies of keratins in hair find broken proteins
Date: Mar 1, 2012
Author: Steve Down
A comprehensive proteomics study of the proteins in human hair by two complementary approaches has provided a broad picture of the keratins and keratin-associated proteins and also revealed a set of broken keratins.
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Journal Highlight: Analysis of proteome and frost tolerance in chromosome 5A and 5B reciprocal substitution lines between two winter wheats during long-term cold acclimation
Date: Feb 27, 2012
Author:
The dynamics of cold tolerance and crown proteome composition have been analysed in a set of two winter wheat cultivars Mironovskaya 808 and Bezostaya 1 and four reciprocal substitution lines with interchanged chromosomes 5A and 5B during a long-term cold-acclimation treatment.
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Prostate cancer proteomic test: Use of biomarker panel before biopsy improves diagnoses and saves money
Date: Feb 15, 2012
Author: Steve Down
A diagnostic test for prostate cancer based on the urinary proteome that was devised in 2008 has been applied in the clinical setting in Germany, providing a cost effective confirmation for patients who have tested positive for prostate-specific antigen and avoiding unnecessary biopsies.
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Bloody battle of the sexes: Male and female plasma have different protein profiles
Date: Feb 1, 2012
Author: Steve Down
A comparative study of the protein contents in male and female human plasma has revealed some important differences which could be exploited to prevent the occurrence of transfusion-related acute lung injury which can occur following blood transfusion.
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Journal Highlight: Proteomics applied to exercise physiology: A cutting-edge technology
Date: Jan 30, 2012
Author:
This review gives an overview of the directions in which exercise-proteome research is moving and examines the main tools that can be used as a novel strategy in exercise physiology investigation.
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Improving bioimplants: Identifying proteins on modified titanium surfaces
Date: Jan 16, 2012
Author: Steve Down
Proteins adsorbed onto the surfaces of titanium-based biomaterials that are used as implants and artificial joints have been identified by a proteomics technique which could lead to the development of novel materials with improved bioreactivity.
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The big picture: Ancient proteins identified in preserved woolly mammoth bone
Date: Jan 5, 2012
Author: Steve Down
A record number of ancient proteins have been isolated and identified from the femur of a 43,000 year-old woolly mammoth that had been preserved in permafrost, using specially developed techniques to minimise contamination along with high-resolution mass spectrometry.
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Journal Highlight: Mass spectrometry-based proteomics approaches applied in cataract research
Date: Dec 15, 2011
Author:
New mass spectrometry-based approaches that are being applied to lens research were highlighted and the future direction of proteomics cataract research was outlined. Mass spectrometry hold great promise to determine which crystallin post-translational modifications lead to a cataract.
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Cloned cat deficiencies: Protein changes account for premature deaths
Date: Dec 15, 2011
Author: Steve Down
The unacceptably low survival rate of cloned animals might be related to the aberrant expression of proteins associated with oxidative damage, apoptosis and senescence, say Korean scientists. The restoration of normal placental protein levels could increase the efficiency and help to save endangered species.
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Growth factor find: Customs seizure contains illicit fibroblast growth factor
Date: Dec 1, 2011
Author: Steve Down
An unknown black market product seized by German customs agents was found to contain fibroblast growth factor, say European scientists. The protein, which has not been given full clinical approval, was probably intended for illegal sports doping.
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