Proteomics & Genomics / Ezine
Bloody battle of the sexes: Male and female plasma have different protein profiles
Date: Feb 1, 2012
Author: Steve Down
A comparative study of the protein contents in male and female human plasma has revealed some important differences which could be exploited to prevent the occurrence of transfusion-related acute lung injury which can occur following blood transfusion.
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Journal Highlight: Proteomics applied to exercise physiology: A cutting-edge technology
Date: Jan 30, 2012
Author:
This review gives an overview of the directions in which exercise-proteome research is moving and examines the main tools that can be used as a novel strategy in exercise physiology investigation.
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Improving bioimplants: Identifying proteins on modified titanium surfaces
Date: Jan 16, 2012
Author: Steve Down
Proteins adsorbed onto the surfaces of titanium-based biomaterials that are used as implants and artificial joints have been identified by a proteomics technique which could lead to the development of novel materials with improved bioreactivity.
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The big picture: Ancient proteins identified in preserved woolly mammoth bone
Date: Jan 5, 2012
Author: Steve Down
A record number of ancient proteins have been isolated and identified from the femur of a 43,000 year-old woolly mammoth that had been preserved in permafrost, using specially developed techniques to minimise contamination along with high-resolution mass spectrometry.
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Journal Highlight: Mass spectrometry-based proteomics approaches applied in cataract research
Date: Dec 15, 2011
Author:
New mass spectrometry-based approaches that are being applied to lens research were highlighted and the future direction of proteomics cataract research was outlined. Mass spectrometry hold great promise to determine which crystallin post-translational modifications lead to a cataract.
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Cloned cat deficiencies: Protein changes account for premature deaths
Date: Dec 15, 2011
Author: Steve Down
The unacceptably low survival rate of cloned animals might be related to the aberrant expression of proteins associated with oxidative damage, apoptosis and senescence, say Korean scientists. The restoration of normal placental protein levels could increase the efficiency and help to save endangered species.
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Growth factor find: Customs seizure contains illicit fibroblast growth factor
Date: Dec 1, 2011
Author: Steve Down
An unknown black market product seized by German customs agents was found to contain fibroblast growth factor, say European scientists. The protein, which has not been given full clinical approval, was probably intended for illegal sports doping.
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Journal Highlight: The Human Protein Atlas as a proteomic resource for biomarker discovery
Date: Nov 21, 2011
Author:
The current status of the Human Protein Atlas project, which provides an important source of information for numerous biomedical research projects, including biomarker discovery efforts, is reviewed.
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Immunity protein pointers: Truncated protein is risk factor for respiratory viral infection in boys
Date: Nov 15, 2011
Author: Steve Down
Several innate immunity proteins have been identified in the nasal lavage fluid of small children suffering from a respiratory virus infection, including full-length and truncated versions of an antibacterial protein which were implicated in higher risk factors for infant boys.
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Memorable proteins: Spatial learning instigates short-term changes in protein abundances in the brain
Date: Nov 1, 2011
Author: Steve Down
The protein changes occurring in the part of the brain that deals with new memories have been charted during a spatial learning activity by rats in an international study which revealed two discrete change phases within 12 hours of training.
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