Proteomics & Genomics / Ezine
Oiling the toxic wheels: Evidence for the role of haptoglobin phenotypes in toxic oil syndrome
Date: Aug 15, 2011
Author: Steve Down
One of the risk factors associated with toxic oil syndrome has been identified in proteomics studies as a phenotype of haptoglobin, with a different phenotype affording protection, according to researchers in Spain where the disease struck.
Read More
The evil twin: Ocean acidification affects proteome of growing barnacles
Date: Aug 1, 2011
Author: Steve Down
Ocean acidification alters the proteome of the larvae of an ecologically important barnacle species, to a small but significant extent. Molecular chaperones and proteins related to energy metabolism and respiration had altered expression levels, hinting at the adopted mechanism for coping with acidification stress.
Read More
Journal Highlight: A roadmap for successful applications of clinical proteomics
Date: Jul 25, 2011
Author:
A roadmap for improving the success rate of clinical proteomics includes steps for improvements that need to be made in analytical tools, discovery, validation, clinical application, and post-clinical application appraisal.
Read More
Busy as a bee: Antennal proteome differences for workers and drones
Date: Jul 15, 2011
Author: Steve Down
The proteomes of the antennae of two castes of bees reflect their different activities, promoting foraging activity in the forager honeybees and sex pheromone detection in mature drone bees, say researchers in China.
Read More
Liver transplant rejection diagnosis: Proteomics study leads to ELISA test
Date: Jul 1, 2011
Author: Steve Down
An ELISA method for the prediction of acute cellular rejection in liver transplant patients with high sensitivity and specificity has been derived on the basis of proteins identified from a proteomic study of patient serum.
Read More
Journal Highlight: Effect of condensed tannin ingestion in sheep and goat parotid saliva proteome
Date: Jun 27, 2011
Author:
Changes in the parotid saliva protein profiles of sheep (Ovis aries) and goats (Capra hircus) induced by condensed tannin ingestion were studied, revealing some species-specific differences in response to quebracho tannin consumption.
Read More
Sorting shrimps: Tandem mass spectrometry monitoring for species discrimination
Date: Jun 15, 2011
Author: Steve Down
Closely related species of shrimp which are difficult to identify by sight have been differentiated by an MS/MS ion monitoring technique using a single precursor ion per species selected from the same protein. The rapid technique is suitable for food safety and labelling applications.
Read More
Childhood obesity signals: Protein family abundances altered
Date: Jun 1, 2011
Author: Steve Down
Obesity and overweight in children is associated with changes in the expression profiles of plasma apolipoproteins, which might manifest themselves before the well-documented alterations in cholesterol levels, say Greek researchers.
Read More
Journal Highlight: Combinatorial peptide ligand libraries: The conquest of the hidden proteome advances at great strides
Date: May 23, 2011
Author:
The combinatorial peptide ligand library (CPLL) has been compared with the immuno-depletion method for evaluating their respective abilities in digging deeper and deeper into the low-abundance proteome.
Read More
It's meat, but not as we know it: Mechanically recovered chicken detected by marker proteins
Date: May 15, 2011
Author: Steve Down
Mechanically recovered chicken meat can be distinguished from hand-deboned chicken using particular proteins as marker compounds, say scientists in the UK, who used off-gel electrophoresis for preliminary fractionation in a proteomics comparison of the two types of meat product.
Read More
