Proteomics & Genomics / Ezine
Busy as a bee: Antennal proteome differences for workers and drones
Date: Jul 15, 2011
Author: Steve Down
The proteomes of the antennae of two castes of bees reflect their different activities, promoting foraging activity in the forager honeybees and sex pheromone detection in mature drone bees, say researchers in China.
Read More
Liver transplant rejection diagnosis: Proteomics study leads to ELISA test
Date: Jul 1, 2011
Author: Steve Down
An ELISA method for the prediction of acute cellular rejection in liver transplant patients with high sensitivity and specificity has been derived on the basis of proteins identified from a proteomic study of patient serum.
Read More
Journal Highlight: Effect of condensed tannin ingestion in sheep and goat parotid saliva proteome
Date: Jun 27, 2011
Author:
Changes in the parotid saliva protein profiles of sheep (Ovis aries) and goats (Capra hircus) induced by condensed tannin ingestion were studied, revealing some species-specific differences in response to quebracho tannin consumption.
Read More
Sorting shrimps: Tandem mass spectrometry monitoring for species discrimination
Date: Jun 15, 2011
Author: Steve Down
Closely related species of shrimp which are difficult to identify by sight have been differentiated by an MS/MS ion monitoring technique using a single precursor ion per species selected from the same protein. The rapid technique is suitable for food safety and labelling applications.
Read More
Childhood obesity signals: Protein family abundances altered
Date: Jun 1, 2011
Author: Steve Down
Obesity and overweight in children is associated with changes in the expression profiles of plasma apolipoproteins, which might manifest themselves before the well-documented alterations in cholesterol levels, say Greek researchers.
Read More
Journal Highlight: Combinatorial peptide ligand libraries: The conquest of the hidden proteome advances at great strides
Date: May 23, 2011
Author:
The combinatorial peptide ligand library (CPLL) has been compared with the immuno-depletion method for evaluating their respective abilities in digging deeper and deeper into the low-abundance proteome.
Read More
It's meat, but not as we know it: Mechanically recovered chicken detected by marker proteins
Date: May 15, 2011
Author: Steve Down
Mechanically recovered chicken meat can be distinguished from hand-deboned chicken using particular proteins as marker compounds, say scientists in the UK, who used off-gel electrophoresis for preliminary fractionation in a proteomics comparison of the two types of meat product.
Read More
Proteomics of cold-adapted microorganism: three distinct physiological states exist over growth temperature range
Date: May 2, 2011
Author: Steve Down
The response of the proteome of a cold-adapted microorganism to temperatures across its complete growth range has revealed three physiological states corresponding to cold stress, cold adaptation and heat stress.
Read More
Journal Highlight: Toward a standardized urine proteome analysis methodology
Date: Apr 25, 2011
Author:
A systematic study has been undertaken to define standardized and integrated analytical protocols for a biomarker development pipeline, employing two LC-MS analytical platforms, namely accurate mass and time tags and selected reaction monitoring, for the discovery and verification phase, respectively.
Read More
Immunodepletion explored: biomarker discovery assisted by increased depletion
Date: Apr 13, 2011
Author: Steve Down
A systematic study of the immunodepletion of clinical serum samples using commercial columns in the search for biomarkers revealed that subsequent bottom-up experiments with a high-resolution mass spectrometer showed excellent reproducibility and a wider range of identified proteins than 2D differential gel electrophoresis.
Read More
