Raman Spectroscopy / Ezine
Sensitive SERS beats ELISA
Date: Apr 1, 2009
Author: David Bradley
Scientists in South Korea have developed a new magnetic approach to immunoassay detection of important biological marker compounds and antigens using surface-enhanced Raman spectroscopy (SERS) of hollow gold nanospheres. The technique is not only much faster than standard assays but up to 1000 times more sensitive.
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Disease recognition by infrared and Raman spectroscopy
Date: Mar 2, 2009
Author:
Infrared and Raman spectroscopy are emerging biophotonic tools to recognize various diseases. This review gives an overview of the experimental techniques, data-classification algorithms and applications to assess soft tissues, hard tissues and body fluids.
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Sperm assessment
Date: Mar 1, 2009
Author: David Bradley
Raman spectroscopy could enable fertility researchers and IVF clinicians to assess individual sperm. The process involves capturing an individual sperm cell between two highly focused beams of laser light with Raman pinning down features of the trapped wriggler's DNA.
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Surface-enhanced Raman scattering spectroscopy via gold nanostars
Date: Feb 2, 2009
Author:
The SERS activities of star-shaped gold nanoparticles tested using 2-mercaptopyridine and crystal violet probing molecules were stronger than that of spherical gold nanoparticles if similar size.
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Date rape analysis
Date: Feb 1, 2009
Author: David Bradley
Raman spectroscopy has been used to identify the date rape drug GHB and its precursor GBL in simulated spiked drinks. Importantly, the technique can be used with a wide variety of beverages in different types of containers included coloured glass, plastic beakers, and polythene bags.
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Nanomechanics of single silkworm and spider fibres: a Raman and micro-mechanical in situ study
Date: Jan 5, 2009
Author:
Micro-Raman spectroscopy and an advanced universal fibre tester were used to probe at the nanoscale the change in conformation, macromolecular fibroin chain orientation and coupling during the application of stress in single fibres three of silkworms and one spider.
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Tweezing out leukaemia spectra
Date: Jan 1, 2009
Author: David Bradley
US researchers have used laser tweezers Raman spectroscopy (LTRS) to help them characterize the effects of different chemical fixation procedures on the spectra of healthy cells and leukaemia cells and to preclude the misinterpretation of data.
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Catalytic chlorinated cleanup
Date: Dec 1, 2008
Author: David Bradley
US researchers have used surface-enhanced Raman spectroscopy (SERS) to reveal the structure and makeup of molecules sitting on the surface of palladium-covered gold nanoshell particles. The work could lead to an improved method for cleaning up the stubborn pollutant TCE (trichloroethene).
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Barcoding bacterial cells: a SERS-based methodology for pathogen identification
Date: Dec 1, 2008
Author:
A principal component analysis based on the sign of the second derivative of the surface-enhanced Raman scattering spectrum obtained on in situ grown Au-cluster-covered SiO2 substrates results in improved reproducibility and enhanced specificity for bacterial diagnostics.
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Resonance Raman monitoring of lipid oxidation in muscle foods
Date: Nov 3, 2008
Author:
Resonance Raman spectroscopy was used to follow the progression of lipid oxidation in mechanically separated turkey (MST) through oxidative bleaching of beta-carotene.
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