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Cancer signals: Enhancing Raman endoscopy

Date: Jul 1, 2011

Author: David Bradley

Radioactively labelled gold nanoparticles can assist in a novel endoscopic technique using Raman spectroscopy to look at microscopic structures, including nascent tumours, deep within the body. Preclinical tests carried out using the technology shows that the gold nanoparticles can be administered safely and used to image the inside of the large intestine. The research bodes well for identification of malignant tissue in the earliest stages of colon cancer.

Read More thumbnail image: Cancer signals Enhancing Raman endoscopy

Journal Highlight: Rapid detection of ricin in milk using immunomagnetic separation combined with surface-enhanced Raman spectroscopy

Date: Jun 6, 2011

Author:

A rapid method that combined immunomagnetic separation and surface-enhanced Raman spectroscopy has been demonstrated for the detection of ricin in whole milk, the feasibility of a portable Raman instrument showing great promise for on-site detection in a processing facility.

Read More thumbnail image: Journal Highlight Rapid detection of ricin in milk using immunomagnetic separation combined with surface-enhanced Raman spectroscopy

Pure uranium: a Raman first

Date: Jun 1, 2011

Author: David Bradley

Scientists at the Indira Gandhi Centre for Atomic Research in Tamil Nadu have carried out the first study of "pure" uranium using Raman spectroscopy. The fundamental research offers new insights into this radioactive metal and may even have implication for developments in nuclear energy.

Read More thumbnail image: Pure uranium a Raman first

Journal Highlight: Raman spectroscopic mapping of the carbon and PTFE distribution in gas diffusion layers

Date: May 2, 2011

Author:

Raman microspectroscopy was used to gather spatially resolved chemical information on the carbon and poly(tetrafluoroethylene) distribution of fuel cell gas diffusion layers.

Read More thumbnail image: Journal Highlight Raman spectroscopic mapping of the carbon and PTFE distribution in gas diffusion layers

Sloshing charge: the origin of SERS

Date: May 1, 2011

Author: David Bradley

New quantum calculations show how electrical charge can slosh from a target molecule to the metal being used to enhance Raman signals in Surface-enhanced Raman spectroscopy (SERS). The finding could finally explain the mechanism by which this technique boosts Raman spectra in terms of the chemical contribution to the effect.

Read More thumbnail image: Sloshing charge the origin of SERS

Journal Highlight: Reliable and non-destructive Raman analysis to determine the urea concentration in a cream formulation

Date: Apr 4, 2011

Author:

A reliable and nondestructive analytical method for the determination of urea concentration in a pharmaceutical cream formulation using Raman spectroscopy gave accurate results despite the spectral collection being performed through plastic bottles.

Read More thumbnail image: Journal Highlight Reliable and non-destructive Raman analysis to determine the urea concentration in a cream formulation

Testing times for beta-carotene and relatives: Raman clues to cosmeceuticals

Date: Apr 1, 2011

Author: David Bradley

While cosmetic manufacturers tend to avoid producing actual medical effects in skin for fear of their products being subsumed into the pharmaceutical regulatory process, there is a need to understand how so-called "cosmeceuticals" might affect the aging process in skin. Resonance Raman spectroscopy has now been used to study non-invasively the interaction of carotenoid antioxidants with free radicals in the skin.

Read More thumbnail image: Testing times for beta-carotene and relatives Raman clues to cosmeceuticals

Journal Highlight: Raman spectroscopy for the analysis of coal: a review

Date: Mar 7, 2011

Author:

Work published on the Raman characterization of the natural organic matter of coals has been reviewed and preliminary results of the natural inorganic matter of various South African coals were reported.

Read More thumbnail image: Journal Highlight Raman spectroscopy for the analysis of coal a review

Rock and awe: Raman discredits microbial fossils

Date: Mar 1, 2011

Author: David Bradley

The oldest fossils of bacteria ever found were discovered in a rock formation in Western Australia, the discovery led to great excitement that has not abated for two decades. Until now. Raman spectroscopy now shows that what palaeontologists thought were pristine microbial fossils may not be anything more complex than chunks of ancient Australian rock.

Read More thumbnail image: Rock and awe Raman discredits microbial fossils

Golden pop: nanoparticles for SERS

Date: Feb 1, 2011

Author: David Bradley

Gold nanoparticles that resemble tiny popcorn kernels can be produced using a simple two-step process. Researchers at Jackson State University in the US have used these particles in SERS experiments to detect malignant prostate cancer at just the 50-cell level. The same particles can also be activated to kill the cells.

Read More thumbnail image: Golden pop nanoparticles for SERS
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