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Universal detector

Date: Sep 1, 2008

Author: David Bradley

A team in Japan has used UV spectroscopy and microscopy to study the interaction between liposome clusters and endocrine-disrupting chemicals (EDCs) as a model of how living cell plasma membranes might be affected. The work could lead to the development of a universal detector for EDCs.

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Detection of pretreated fingerprint fluorescence using an LED-based excitation system

Date: Aug 11, 2008

Author:

Optimization of a light emitting diode (LED)-based excitation system for the detection of pretreated fingerprint fluorescence is described. It employs blue and green LED arrays composed of ninety LED units with suitable low pass filters.

Read More thumbnail image: Detection of pretreated fingerprint fluorescence using an LED-based excitation system

Summer screen

Date: Aug 1, 2008

Author: David Bradley

Wear sunscreen! It has been the advice of the medical profession, governments, and parents everywhere for several years. But, a report published this summer by the Environmental Working Group suggests that many popular sun protection products are at best ineffective, and at worst hazardous to health.

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Optical spectroscopy of single-walled carbon nanotubes: From excitonic effects towards control of the radiative lifetime

Date: Jul 14, 2008

Author:

The radiative lifetime of single-walled carbon nanotubes has been enhanced by exciton coupling to surface plasmon polaritons in metallic nanostructures, as illustrated by their two-photon liminescence spectra.

Read More thumbnail image: Optical spectroscopy of single-walled carbon nanotubes From excitonic effects towards control of the radiative lifetime

Testing time for testosterone

Date: Jul 1, 2008

Author: David Bradley

A new analytical approach to testing for testosterone and related steroids in body fluids using non-specific micellar electrokinetic chromatography (MEKC) has been developed. The partial filling (PF) technique was employed, which means the approach is suitable for detection by either ultraviolet spectrophotometry or electrospray ionization mass spectrometry.

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The protein fluorescence and structural toolkit: Database and programs for protein fluorescence and structural data

Date: Jun 9, 2008

Author:

Individual software modules developed previously for fluorescence and structural analyses have been integrated and a new program for the assignment of tryptophan residues to spectral-structural classes has been introduced. They form part of a web-based protein fluorescence and structural toolkit (PFAST).

Read More thumbnail image: The protein fluorescence and structural toolkit Database and programs for protein fluorescence and structural data

For buckyballs, size really does matter

Date: Jun 1, 2008

Author: David Bradley

US researchers are using ultraviolet spectroscopy and other techniques to help them answer the question - how does the reactivity of metallofullerenes correlate with the size of the cage? Their work could lead to the further development of more effective contrast agents for magnetic resonance imaging (MRI).

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Application of optical non-invasive methods in skin physiology

Date: May 12, 2008

Author:

The application of optical noninvasive methods in dermatology and cosmetology is discussed, laser scanning microscopy and optical coherent tomography being the most promising methods for this application.

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Fishing for amines

Date: May 1, 2008

Author: David Bradley

Analysis of low-molecular-weight amines is crucial in biomedical research, medical diagnostics, environmental science, and food safety. Now, UV/Vis spectroscopy has assisted the development of new fluorescent compounds that glow in the presence of specific amines for sensor applications.

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Toward quantitative fluorescence measurements with multicolor flow cytometry

Date: Apr 14, 2008

Author:

A two-step procedure is presented for calibrating the output of a multicolor flow cytometer in units of antibodies bound per cell. The fluorescence channels of the flow cytometer are calibrated using Ultra Rainbow beads. The second step involves a biological standard such as a lymphocyte with a known number of antibody binding sites.

Read More thumbnail image: Toward quantitative fluorescence measurements with multicolor flow cytometry
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