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For buckyballs, size really does matter

Date: Jun 1, 2008

Author: David Bradley

US researchers are using ultraviolet spectroscopy and other techniques to help them answer the question - how does the reactivity of metallofullerenes correlate with the size of the cage? Their work could lead to the further development of more effective contrast agents for magnetic resonance imaging (MRI).

Read More thumbnail image: For buckyballs size really does matter

Application of optical non-invasive methods in skin physiology

Date: May 12, 2008

Author:

The application of optical noninvasive methods in dermatology and cosmetology is discussed, laser scanning microscopy and optical coherent tomography being the most promising methods for this application.

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Fishing for amines

Date: May 1, 2008

Author: David Bradley

Analysis of low-molecular-weight amines is crucial in biomedical research, medical diagnostics, environmental science, and food safety. Now, UV/Vis spectroscopy has assisted the development of new fluorescent compounds that glow in the presence of specific amines for sensor applications.

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Toward quantitative fluorescence measurements with multicolor flow cytometry

Date: Apr 14, 2008

Author:

A two-step procedure is presented for calibrating the output of a multicolor flow cytometer in units of antibodies bound per cell. The fluorescence channels of the flow cytometer are calibrated using Ultra Rainbow beads. The second step involves a biological standard such as a lymphocyte with a known number of antibody binding sites.

Read More thumbnail image: Toward quantitative fluorescence measurements with multicolor flow cytometry

Green fireworks

Date: Apr 1, 2008

Author: David Bradley

Visible spectroscopy is key to the search for green fireworks, not only figuratively but from the literal position of searching for environment friendly bangs and flashes.

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Micro-Raman and fluorescence spectroscopy to study the effects of light exposure on films of egg white and egg yolk

Date: Mar 10, 2008

Author:

Non-destructive techniques were employed for the spectrofluorimetric and micro-Raman differentiation of solid films of egg yolk and egg white as a function of exposure to light. They allowed the discrimination of samples based on composition.

Read More thumbnail image: Micro-Raman and fluorescence spectroscopy to study the effects of light exposure on films of egg white and egg yolk

Breathe easy when you're in the swim

Date: Mar 1, 2008

Author: David Bradley

US researchers are learning how to reduce the production of irritating and unhealthy volatile compounds in swimming pools by turning to ultraviolet technology to complement the use of chlorinated disinfectants.

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Isocratic LC with segmented columns and multiple detection for selectivity enhancement in the determination of explosives

Date: Feb 11, 2008

Author:

The concept of stationary-phase optimized LC was studied in the context of separation and detection aspects for the determination of explosives. A tailor-made segmented column assembly with 3 complementary RP materials enabled the separation of 14 priority target nitroaromatic explosives.

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Bird with a healthy flush

Date: Feb 1, 2008

Author: David Bradley

The bright-red throat pouch of the male great frigate bird impresses the female of the species. Now, US researchers have discovered the underlying chemistry that gives him such an attractive throat pouch and hint that the display could be more than cosmetic, acting an indicator of his health.

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Fluorescence correlation spectroscopy for probing the kinetics and mechanisms of DNA hairpin formation

Date: Jan 14, 2008

Author:

This article reviews the application of fluorescence correlation spectroscopy (FCS) and related techniques to the study of nucleic acid hairpin conformational fluctuations in free aqueous solutions.

Read More thumbnail image: Fluorescence correlation spectroscopy for probing the kinetics and mechanisms of DNA hairpin formation
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