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Adenine pathways: UV protection racket

Date: Sep 1, 2011

Author: David Bradley

A collaboration between teams in Germany and the US has shown that one of the building blocks of the nucleic acids DNA and RNA, adenine, has a previously unrecognised variable range of ionization energies along its reaction pathways. The finding could improve our understanding of experimental data regarding how adenine survives exposure to ultraviolet light, showing that the processes might be more complicated than previously thought. However, it also has potentially far-reaching implications for...

Read More thumbnail image: Adenine pathways UV protection racket

Journal Highlight: Automated classification of multicolored rolling circle products in dual-channel wide-field fluorescence microscopy

Date: Aug 8, 2011

Author:

Image analysis methods are presented for the detection and classification of single molecules and single-molecule interactions detected using padlock probes or proximity ligation.

Read More thumbnail image: Journal Highlight Automated classification of multicolored rolling circle products in dual-channel wide-field fluorescence microscopy

Sunburn solution: UV damage pivots on single electron

Date: Aug 1, 2011

Author: David Bradley

Researchers who have been working for nearly a decade to piece together the process by which an enzyme repairs UV-damaged DNA have finally witnessed the entire process in full detail in the laboratory and it seems just one electron underpins the whole process pointing to a potential treatment for sunburn.

Read More thumbnail image: Sunburn solution UV damage pivots on single electron

Journal Highlight: Synchronous fluorescence spectroscopy as a novel tool to enable PAT applications in bioprocesses

Date: Jul 11, 2011

Author:

Synchronous fluorescence spectroscopy was evaluated as a new tool for real-time bioprocess monitoring of animal cell cultures using bioreactor cultures of three monoclonal antibody-producing CHO cell lines. The technique provides data on various fluorescent compounds in a single spectrum, showing improved peak resolution and recording speed.

Read More thumbnail image: Journal Highlight Synchronous fluorescence spectroscopy as a novel tool to enable PAT applications in bioprocesses

Inked up: Electrophoresis spots forged documents

Date: Jul 1, 2011

Author: David Bradley

Discriminating between original documents produced using an inkjet printer is now much easier and could be used in forensic analysis to spot forgeries and counterfeit documents through the coupling of micellar electrophoretic capillary chromatography (MECC) and UV-Vis spectroscopic data.

Read More thumbnail image: Inked up Electrophoresis spots forged documents

Journal Highlight: On site noninvasive assessment of peri-implant inflammation by optical spectroscopy

Date: Jun 13, 2011

Author:

The diagnostic potential of optical spectroscopy in peri-implant inflammation in vivo was evaluated by assessing multiple inflammatory parameters (tissue oxygenation, total tissue hemoglobin, deoxyhemoglobin, oxygenated hemoglobin and tissue edema) simultaneously.

Read More thumbnail image: Journal Highlight On site noninvasive assessment of peri-implant inflammation by optical spectroscopy

Hold the Maya: ancient pigments analysed

Date: Jun 1, 2011

Author: David Bradley

UV-Vis spectroscopy and various other techniques have been used to analyse the yellow pigments found in Mayan wall paintings. The compouns present are the indigoids, including isatin and dehydroindigo. The spectra together with SEM/EDX, TEM and voltammetry of microparticles show that this ancient people had the recipe for making indigo itself and converting it to Maya Blue and Maya Yellow in a stepwise reaction sequence.

Read More thumbnail image: Hold the Maya ancient pigments analysed

Journal Highlight: Fluorescence spectroscopy characterization of cadmium sulfide quantum dots on metal, insulator, and semiconductor substrates

Date: May 9, 2011

Author:

Fluorescence spectroscopy has been used to identify the range and maxima of excitation and emission spectra of colliodal cadmium sulfide quantum dots capped with dioctyl sulfosuccinate, deposited upon substrates of gold, mica and gallium arsenide.

Read More thumbnail image: Journal Highlight Fluorescence spectroscopy characterization of cadmium sulfide quantum dots on metal insulator and semiconductor substrates

Cloudy correction: spectral change needed

Date: May 1, 2011

Author: David Bradley

Atmospheric and climate models may have overlooked the fact that exactly how clouds appear to reduce the amount of sunlight available for warming the surface of the earth depends on the wavelength being measured across the spectrum from infrared to ultraviolet. The finding could now help researchers improve climate models by factoring in the effects of cloud cover more precisely.

Read More thumbnail image: Cloudy correction spectral change needed

Journal Highlight: Accuracy of optical spectroscopy for the detection of cervical intraepithelial neoplasia: Testing a device as an adjunct to colposcopy

Date: Apr 11, 2011

Author:

An effective classification algorithm was derived for optical spectroscopy as an adjunct to colposcopy and preliminary estimates of its accuracy were obtained for the detection of cervical intraepithelial neoplasia or worse.

Read More thumbnail image: Journal Highlight Accuracy of optical spectroscopy for the detection of cervical intraepithelial neoplasia Testing a device as an adjunct to colposcopy
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