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Tracing of intracellular zinc(II) fluorescence flux to monitor cell apoptosis by using FluoZin-3AM

Date: Oct 12, 2009

Author:

The zinc(II) probe FluoZin-3AM was used to distinguish between different stages of apoptotic cell (induced by the anticancer agent etoposide) by tracing the intracellular zinc(II) fluorescence flux.

Read More thumbnail image: Tracing of intracellular zincII fluorescence flux to monitor cell apoptosis by using FluoZin-3AM

Optical sniffer detects poison gas

Date: Oct 1, 2009

Author: David Bradley

US researchers have developed an optoelectronic nose that can sniff out toxic gases. The sensor is fast and inexpensive and could be used to detect high exposure risk to hazardous industrial chemicals.

Read More thumbnail image: Optical sniffer detects poison gas

Fluorescence of unmodified oligonucleotides: A tool to probe G-quadruplex DNA structure

Date: Sep 14, 2009

Author:

Unlabelled oligonucleotides that form G-quadruplexes can be differentiated from similar sequences that do not contain consecutive guanines on the basis of their fluorescence spectra.

Read More thumbnail image: Fluorescence of unmodified oligonucleotides A tool to probe G-quadruplex DNA structure

One from the vine

Date: Sep 1, 2009

Author: David Bradley

Kudzu is a weedy vine that has overgrown almost 10 million acres in the southeastern United States. However, it could one day sprout into a dietary supplement to helpe reduce metabolic syndrome in millions of people. Mass spectrometry and UV spectroscopy have now been used to identify and quantify the putatively active isoflavones in extracts of the vine by US scientists.

Read More thumbnail image: One from the vine

Nonlinear optical spectroscopy of soft matter interfaces

Date: Aug 10, 2009

Author:

New developments that enable us to obtain detailed molecular structural changes in the topmost molecular layers of soft matter interfaces composed of complex bio-molecules are reviewed. In particular, the possibilities to probe interfaces of colloidal soft matter systems are discussed.

Read More thumbnail image: Nonlinear optical spectroscopy of soft matter interfaces

Microbial nanotechnologists

Date: Aug 1, 2009

Author: David Bradley

The bacterium Bacillus licheniformis is an expert nanotechnologist, according to scientists in India. They have used the microbe to help them synthesise gold nanocubes, as verified by UV spectroscopy and other techniques. The approach offers an alternative approach to making these important nanoparticles without using high temperatures or toxic solvents.

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Optical spectroscopy of InGaN-GaN quantum dot ensembles

Date: Jul 13, 2009

Author:

InGaN-GaN quantum dots grown with variations in the deposition time to vary their properties were studied by atomic force microscopy and photoluminescence spectroscopy.

Read More thumbnail image: Optical spectroscopy of InGaN-GaN quantum dot ensembles

Cast-iron protection racket

Date: Jul 1, 2009

Author: David Bradley

Little is known about how the haem group that carries oxygen in blood and is the active centre of several enzymes is transported from where it is made in the cell to its host protein assembly. Now, UV-Vis spectroscopy has helped identify an enzyme that also functions as a haem transporter.

Read More thumbnail image: Cast-iron protection racket

Fluorescence microscopy and flow cytometry in measuring activated caspases in human spermatozoa

Date: Jun 8, 2009

Author:

Staining of spermatozoa with fluorescein-Val-Ala-Asp-fluoromethylketone using fluorescence microscopy or flow cytometry to score activated caspases was compared in order to adopt the most accurate method for detection in human frozen-thawed testicular, epididymal and ejaculated spermatozoa.

Read More thumbnail image: Fluorescence microscopy and flow cytometry in measuring activated caspases in human spermatozoa

Bi-curious cylinders

Date: Jun 1, 2009

Author: David Bradley

A team in the US has produced micrometre-wide discs and elongated rods from bi-coloured and multicolored compartments. The researchers used fluorescent emission studies and scanning electron microscopy to characterise their products.

Read More thumbnail image: Bi-curious cylinders
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