UV/Vis Spectroscopy / Ezine
Adenine pathways: UV protection racket
Date: Sep 1, 2011
Author: David Bradley
A collaboration between teams in Germany and the US has shown that one of the building blocks of the nucleic acids DNA and RNA, adenine, has a previously unrecognised variable range of ionization energies along its reaction pathways. The finding could improve our understanding of experimental data regarding how adenine survives exposure to ultraviolet light, showing that the processes might be more complicated than previously thought. However, it also has potentially far-reaching implications for...
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Journal Highlight: Automated classification of multicolored rolling circle products in dual-channel wide-field fluorescence microscopy
Date: Aug 8, 2011
Author:
Image analysis methods are presented for the detection and classification of single molecules and single-molecule interactions detected using padlock probes or proximity ligation.
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Sunburn solution: UV damage pivots on single electron
Date: Aug 1, 2011
Author: David Bradley
Researchers who have been working for nearly a decade to piece together the process by which an enzyme repairs UV-damaged DNA have finally witnessed the entire process in full detail in the laboratory and it seems just one electron underpins the whole process pointing to a potential treatment for sunburn.
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Journal Highlight: Synchronous fluorescence spectroscopy as a novel tool to enable PAT applications in bioprocesses
Date: Jul 11, 2011
Author:
Synchronous fluorescence spectroscopy was evaluated as a new tool for real-time bioprocess monitoring of animal cell cultures using bioreactor cultures of three monoclonal antibody-producing CHO cell lines. The technique provides data on various fluorescent compounds in a single spectrum, showing improved peak resolution and recording speed.
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Inked up: Electrophoresis spots forged documents
Date: Jul 1, 2011
Author: David Bradley
Discriminating between original documents produced using an inkjet printer is now much easier and could be used in forensic analysis to spot forgeries and counterfeit documents through the coupling of micellar electrophoretic capillary chromatography (MECC) and UV-Vis spectroscopic data.
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Journal Highlight: On site noninvasive assessment of peri-implant inflammation by optical spectroscopy
Date: Jun 13, 2011
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The diagnostic potential of optical spectroscopy in peri-implant inflammation in vivo was evaluated by assessing multiple inflammatory parameters (tissue oxygenation, total tissue hemoglobin, deoxyhemoglobin, oxygenated hemoglobin and tissue edema) simultaneously.
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Hold the Maya: ancient pigments analysed
Date: Jun 1, 2011
Author: David Bradley
UV-Vis spectroscopy and various other techniques have been used to analyse the yellow pigments found in Mayan wall paintings. The compouns present are the indigoids, including isatin and dehydroindigo. The spectra together with SEM/EDX, TEM and voltammetry of microparticles show that this ancient people had the recipe for making indigo itself and converting it to Maya Blue and Maya Yellow in a stepwise reaction sequence.
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Journal Highlight: Fluorescence spectroscopy characterization of cadmium sulfide quantum dots on metal, insulator, and semiconductor substrates
Date: May 9, 2011
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Fluorescence spectroscopy has been used to identify the range and maxima of excitation and emission spectra of colliodal cadmium sulfide quantum dots capped with dioctyl sulfosuccinate, deposited upon substrates of gold, mica and gallium arsenide.
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Cloudy correction: spectral change needed
Date: May 1, 2011
Author: David Bradley
Atmospheric and climate models may have overlooked the fact that exactly how clouds appear to reduce the amount of sunlight available for warming the surface of the earth depends on the wavelength being measured across the spectrum from infrared to ultraviolet. The finding could now help researchers improve climate models by factoring in the effects of cloud cover more precisely.
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Journal Highlight: Accuracy of optical spectroscopy for the detection of cervical intraepithelial neoplasia: Testing a device as an adjunct to colposcopy
Date: Apr 11, 2011
Author:
An effective classification algorithm was derived for optical spectroscopy as an adjunct to colposcopy and preliminary estimates of its accuracy were obtained for the detection of cervical intraepithelial neoplasia or worse.
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