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Genotoxic Impurities: Strategies for Identification and Control

Date: Feb 15, 2011

Author: Andrew Teasdale

This book examines genotoxic impurities and their impact on the pharmaceutical industry. Specific sections examine this from both a toxicological and analytical perspective. Within these sections, the book defines appropriate strategies to both assess and ultimately control genotoxic impurities, thus aiding the reader to develop effective control measures. An opening section covers the development of guidelines and the threshold of toxicological concern (TTC) and is followed by a section on...

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Handbook of Alcoholic Beverages: Technical, Analytical and Nutritional Aspects, 2 Volume Set

Date: Jan 28, 2011

Author: Alan J. Buglass

A comprehensive two- volume set that describes the science and technology involved in the production and analysis of alcoholic beverages. At the heart of all alcoholic beverages is the process of fermentation, particularly alcoholic fermentation, whereby sugars are converted to ethanol and many other minor products. The Handbook of Alcoholic Beverages tracks the major fermentation process, and the major chemical, physical and technical processes that accompany the production of the world’s most...

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Analytical Methods for Therapeutic Drug Monitoring and Toxicology

Date: Jan 28, 2011

Author: Q. Alan Xu, Timothy L. Madden

This book is a compilation of summarized analytical methods designed to serve the needs of pharmacologists, toxicologists, and other allied health professionals involved the development, use, or monitoring of pharmaceuticals. The summaries are structured monographs on 511 different drug entities detailing 964 different analytical methods, providing the reader with a thorough description of method validation. These analytical methods include not only high performance liquid chromatography (HPLC), but also...

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Handbook of Fluorescence Spectroscopy and Imaging: From Ensemble to Single Molecules

Date: Jan 26, 2011

Author: Markus Sauer, Johan Hofkens, Jörg Enderlein

Providing much-needed information on fluorescence spectroscopy and microscopy, this ready reference covers detection techniques, data registration, and the use of spectroscopic tools, as well as new techniques for improving the resolution of optical microscopy below the resolution gap. Starting with the basic principles, the book goes on to treat fluorophores and labeling, single-molecule fluorescence spectroscopy and enzymatics, as well as excited state energy transfer, and super-resolution fluorescence...

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Regulated Bioanalytical Laboratories: Technical and Regulatory Aspects from Global Perspectives

Date: Jan 21, 2011

Author: Michael Zhou

This book provides useful information for bioanalytical / analytical scientists, analysts, quality assurance managers, and all personnel in bioanalytical laboratories through all aspects of bioanalytical technical and regulatory perspectives within bioanalytical operations and processes. Readers learn how to develop and implement strategies for routine, non-routine, and standard bioanalytical methods and on the entire equipment hardware and software qualification process. The book also gives guidelines on...

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Raman Spectroscopy in Graphene Related Systems

Date: Jan 14, 2011

Author: Ado Jorio, Mildred S. Dresselhaus, Riichiro Saito, Gene Dresselhaus

Raman spectroscopy is the inelastic scattering of light by matter. Being highly sensitive to the physical and chemical properties of materials, as well as to environmental effects that change these properties, Raman spectroscopy is now evolving into one of the most important tools for nanoscience and nanotechnology. In contrast to usual microscopyrelated techniques, the advantages of using light for nanoscience relate to both experimental and fundamental aspects.

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Surface Enhanced Raman Spectroscopy

Date: Dec 15, 2010

Author: Sebastian Schlucker, Wolfgang Kiefer

Covering everything from the basic theoretical and practical knowledge to new exciting developments in the field with a focus on analytical and life science applications, this monograph shows how to apply surface-enhanced Raman scattering (SERS) for solving real world problems. From the contents: * Theory and practice of SERS * Analytical applications * SERS combined with other analytical techniques * Biophysical applications * Life science applications including various microscopies Aimed at...

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Essential Practical NMR for Organic Chemistry

Date: Dec 10, 2010

Author: S. A. Richards, J. C. Hollerton

This book describes the use of NMR spectroscopy for dealing with problems of small organic molecule structural elucidation. It features a significant amount of vital chemical shift and coupling information but more importantly, it presents sound principles for the selection of the techniques relevant to the solving of particular types of problem, whilst stressing the importance of extracting the maximum available information from the simple 1-D proton experiment and of using this to plan subsequent...

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Modern Methods of Crystal Structure Prediction

Date: Nov 24, 2010

Author: Artem R. Oganov

Gathering leading specialists in the field of structure prediction, this book provides a unique view of this complex and rapidly developing field, reflecting the numerous viewpoints of the different authors. A summary of the major achievements over the last few years and of the challenges still remaining makes this monograph very timely.

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Computational Spectroscopy

Date: Oct 27, 2010

Author: Jorg Grunenberg

Unique in its comprehensive coverage of not only theoretical methods but also applications in computational spectroscopy, this ready reference and handbook compiles the developments made over the last few years, from single molecule studies to the simulation of clusters and the solid state, from organic molecules to complex inorganic systems and from basic research to commercial applications in the area of environment relevance. In so doing, it covers a multitude of apparatus-driven technologies, starting...

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