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Hydrogen Exchange Mass Spectrometry of Proteins

Date: Jul 3, 2015

Author: David Weis

Hydrogen exchange mass spectrometry is widely recognized for its ability to probe the structure and dynamics of proteins. The application of this technique is becoming widespread due to its versatility for providing structural information about challenging biological macromolecules such as antibodies, flexible proteins and glycoproteins. Although the technique has been around for 25 years, this is the first definitive book devoted entirely to the topic. Hydrogen Exchange Mass Spectrometry of Proteins:...

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Organic Stereochemistry: Experimental and Computational Methods

Date: Jun 17, 2015

Author: Hua-Jie Zhu

Adopting a novel approach to the topic by combining theoretical knowledge and practical results, this book presents the most popular and useful computational and experimental methods applied for studying the stereochemistry of chemical reactions and compounds. The text is clearly divided into three sections on fundamentals, spectroscopic and computational techniques, and applications in organic synthesis. The first part provides a brief introduction to the field of chirality and stereochemistry, while the...

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A Primer of NMR Theory

Date: Jun 12, 2015

Author: Alan J. Benesi

Presents the theory of NMR enhanced with Mathematica notebooks Provides short, focused chapters with brief explanations of well-defined topics with an emphasis on a mathematical description Presents essential results from quantum mechanics concisely and for easy use in predicting and simulating the results of NMR experiments Includes Mathematica notebooks that implement the theory in the form of text, graphics, sound, and calculations Based on class tested methods developed by the author over his 25 year...

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Mass Spectrometry for the Analysis of Pesticide Residues and their Metabolites

Date: Jun 2, 2015

Author: Despina Tsipi, Helen Botitsi, Anastasios Economou

Provides an overview of the use of mass spectrometry (MS) for the analysis of pesticide residues and their metabolites. Presents state of the-art MS techniques for the identification of pesticides and their transformation products in food and environment Covers important advances in MS techniques including MS instrumentation and chromatographic separations (e.g. UPLC, HILIC, comprehensive GCxGC) and applications Illustrates the main sample preparation techniques (SPE, QuEChERS, microextraction) used in...

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Instructors Guide and Solutions Manual to Organic Structures from 2D NMR Spectra

Date: May 29, 2015

Author: L. D. Field, H. L. Li, A. M. Magill

The text Organic Structures from 2D NMR Spectra contains a graded set of structural problems employing 2D-NMR spectroscopy. The Instructors Guide and Solutions Manual to Organic Structures from 2D NMR Spectra is a set of step-by-step worked solutions to every problem in Organic Structures from 2D NMR Spectra. While it is absolutely clear that there are many ways to get to the correct solution of any of the problems, the instructors guide contains at least one complete pathway to every one of the questions....

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Organic Structures from 2D NMR Spectra

Date: May 29, 2015

Author: L. D. Field, H. L. Li, A. M. Magill

The derivation of structural information from spectroscopic data is now an integral part of organic chemistry courses at all Universities.  Over recent years, a number of powerful two-dimensional NMR techniques (e.g. HSQC, HMBC, TOCSY, COSY and NOESY) have been developed and these have vastly expanded the amount of structural information that can be obtained by NMR spectroscopy.  Improvements in NMR instrumentation now mean that 2D NMR spectra are routinely (and sometimes automatically) acquired...

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Photonics, Volume 4, Biomedical Photonics, Spectroscopy, and Microscopy

Date: May 19, 2015

Author: David L. Andrews

Discusses the basic physical principles underlying Biomedical Photonics, spectroscopy and microscopy This volume discusses biomedical photonics, spectroscopy and microscopy, the basic physical principles underlying the technology and its applications. The topics discussed in this volume are: Biophotonics; Fluorescence and Phosphorescence; Medical Photonics; Microscopy; Nonlinear Optics; Ophthalmic Technology; Optical Tomography; Optofluidics; Photodynamic Therapy; Image Processing; Imaging Systems;...

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Principles of Inorganic Chemistry

Date: May 15, 2015

Author: Brian W. Pfennig

Aimed at senior undergraduates and first-year graduate students, this book offers a principles-based approach to inorganic chemistry that, unlike other texts, uses chemical applications of group theory and molecular orbital theory throughout as an underlying framework. This highly physical approach allows students to derive the greatest benefit of topics such as molecular orbital acid-base theory, band theory of solids, and inorganic photochemistry, to name a few. Takes a principles-based, group and...

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Analyzing Biomolecular Interactions by Mass Spectrometry

Date: May 15, 2015

Author: Jeroen Kool, Wilfried M. A. Niessen

This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section...

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Pharmaceutical Amorphous Solid Dispersions

Date: May 13, 2015

Author: Ann Newman

Providing a roadmap from early to late stages of drug development, this book overviews amorphous solid dispersion technology – a leading platform to deliver poorly water soluble drugs, a major hurdle in today’s pharmaceutical industry. • Helps readers understand amorphous solid dispersions and apply techniques to particular pharmaceutical systems • Covers physical and chemical properties, screening, scale-up, formulation, drug product manufacture, intellectual property,...

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