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Journal Highlight: Biomarkers of systemic lupus erythematosus identified using mass spectrometry-based proteomics: a systematic review

Date: May 22, 2017

Author: spectroscopyNOW

A systematic review of published reports on proteomic biomarkers identified in systemic lupus erythematosus patients using mass spectrometry-based proteomics has been conducted, highlighting their potential disease association and clinical utility.

Read More thumbnail image: Journal Highlight Biomarkers of systemic lupus erythematosus identified using mass spectrometry-based proteomics a systematic review

Journal Highlight: Toward the automatic quantification of in utero brain development in 3D structural MRI: A review

Date: May 22, 2017

Author: spectroscopyNOW

A review is presented of the major building blocks of the pipeline toward performing quantitative analysis of in vivo MRI of the developing brain and its potential applications in clinical settings.

Read More thumbnail image: Journal Highlight Toward the automatic quantification of in utero brain development in 3D structural MRI A review

Morphine addiction: Enzyme activity

Date: May 16, 2017

Author: Steve Down

Polish scientists have measured the activities of four enzymes in the brain implicated in the mechanism of morphine addiction in the search for therapeutic targets which do not produce the serious side effects during pain treatment.

Read More thumbnail image: Morphine addiction Enzyme activity

Drug double take: Two ambient ionisation techniques for forensic work

Date: May 15, 2017

Author: Steve Down

Scientists with the FBI have adapted two ambient ionisation techniques for the rapid and accurate analysis of illegal drugs, illustrated with black tar heroin and Spice designer drugs.

Read More thumbnail image: Drug double take Two ambient ionisation techniques for forensic work

Slim chance of purity with internet herbal weight loss products

Date: May 15, 2017

Author: Ryan De Vooght-Johnson

So-called ‘herbal’ slimming aids are often adulterated with banned slimming drugs or other chemicals, to increase their effectiveness. Researchers at the Scientific Institute of Public Health in Brussels and the University of Antwerp examined several different samples of such products by UHPLC, classifying them using various chemometric methods, such as hierarchical cluster analysis (HCA), Classification and Regression Tree (CART), and partial least squares discriminant analysis (PLS-DA).

Read More thumbnail image: Slim chance of purity with internet herbal weight loss products

Journal Highlight: Non-destructive detection of dicyandiamide in infant formula powder using multi-spectral imaging coupled with chemometrics

Date: May 15, 2017

Author: spectroscopyNOW

Multi-spectral imaging at 405–970 nm coupled with back-propagation neural networks has been used successfully for the detection of dicyandiamde in infant formula powder.

Read More thumbnail image: Journal Highlight Non-destructive detection of dicyandiamide in infant formula powder using multi-spectral imaging coupled with chemometrics

Modus operando: Better batteries with X-rays

Date: May 15, 2017

Author: David Bradley

Operando X-ray diffraction has been used to elucidate the role of SiO2 (quartz powder) added to the electrolyte (liquid component) in lithium-sulfur battery. Li-S battery is a promising future energy storage system because of it energy density higher than that of conventional lithium-ion batteries. However to date, this system suffers from quickly declining capacity.

Read More thumbnail image: Modus operando Better batteries with X-rays

Cellular signals: NMR metabolic profiling

Date: May 15, 2017

Author: David Bradley

A novel NMR technique developed by researchers at the University of Toronto Scarborough, Canada, can for the first time obtain undistorted high-resolution profiles of the molecules and metabolites present within a living organism.

Read More thumbnail image: Cellular signals NMR metabolic profiling

Selenium sampled: Graphite furnace atomic absorption spectrometry

Date: May 15, 2017

Author: David Bradley

Continuous sample drop flow microextraction coupled with iridium-modified tube graphite furnace atomic absorption spectrometry (GFAAS) offers a new, highly sensitive technique for measuring the trace element selenium in blood samples.

Read More thumbnail image: Selenium sampled Graphite furnace atomic absorption spectrometry

Arsenic and liver: Chicken feed analysis

Date: May 15, 2017

Author: David Bradley

An analysis of mass spectrometric data reveals the existence of three toxicologically important methylated phenylarsenical metabolites in chicken liver from fowl given feed containing the additive 3-nitro-4-hydroxyphenylarsonic acid (ROX). The additive was banned in the European Union in 1999 and in the USA in 2013, but still widely used elsewhere.

Read More thumbnail image: Arsenic and liver Chicken feed analysis
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