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Time for resolution: Single molecule

Date: Sep 1, 2014

Author: David Bradley

For the first time, chemists have succeeded in measuring the vibrational movements of a single molecule with time resolution on the femtosecond scale using time-resolved coherent anti-Stokes Raman scattering.

Read More thumbnail image: Time for resolution Single molecule

Solar power: Crystallographic clues

Date: Aug 27, 2014

Author: David Bradley

An international research team is testing its intellectual strength using serial femtosecond crystallography with a view to teasing apart the proteins involved in photosynthesis, the process by which plants convert solar energy into carbohydrates.

Read More thumbnail image: Solar power Crystallographic clues

Journal Highlight: Iron deposits in post-mortem brains of patients with neurodegenerative and cerebrovascular diseases: a semi-quantitative 7.0 T magnetic resonance imaging study

Date: Aug 25, 2014

Author: spectroscopyNOW

The iron content in post-mortem brains with different neurodegenerative and cerebrovascular diseases has been investigated by T2*-weighted gradient-echo 7.0 T magnetic resonance imaging.

Read More thumbnail image: Journal Highlight Iron deposits in post-mortem brains of patients with neurodegenerative and cerebrovascular diseases a semi-quantitative 7_0 T magnetic resonance imaging study

Journal Highlight: Proteomic strategies for the discovery of novel diagnostic and therapeutic targets for infectious diseases

Date: Aug 25, 2014

Author: spectroscopyNOW

In this review, proteomic information on host–viral protein interactions obtained through differing technologies is compared and ways to determine the functional aspect of the host response to infection are described.

Read More thumbnail image: Journal Highlight Proteomic strategies for the discovery of novel diagnostic and therapeutic targets for infectious diseases

Journal Highlight: Iterative k-t principal component analysis with nonrigid motion correction for dynamic three-dimensional cardiac perfusion imaging

Date: Aug 18, 2014

Author: spectroscopyNOW

An iterative k-t principal component analysis algorithm with nonrigid frame-to-frame motion correction has been proposed for dynamic contrast-enhanced three-dimensional perfusion imaging.

Read More thumbnail image: Journal Highlight Iterative k-t principal component analysis with nonrigid motion correction for dynamic three-dimensional cardiac perfusion imaging

Trypsin autolysis reduced: In-gel digestion improved

Date: Aug 15, 2014

Author: Steve Down

The amount of trypsin used in typical in-gel digestion procedures can be reduced ten-fold at least, without any loss of performance. In fact, some aspects are improved, such as a reduction in the number of trypsin autolysis products and a notable increase in the number of proteins identified in complex samples.

Read More thumbnail image: Trypsin autolysis reduced In-gel digestion improved

Cigarette smoke toxins: Automated SPME-GC/MS with smoking machine

Date: Aug 15, 2014

Author: Steve Down

22 Cigarette toxins which are normally measured by different assays have been determined in one automated procedure using a smoking machine and gas sampling bags for SPME-GC/MS, which will allow the exposure conditions of different brands to be compared.

Read More thumbnail image: Cigarette smoke toxins Automated SPME-GCMS with smoking machine

It's only natural: Metabolomics plugin

Date: Aug 15, 2014

Author: David Bradley

In metabolomics experiments, spectral fingerprints of metabolites with no known structural identity are detected routinely. Researchers in the UK have now taken a cheminformatics approach to this problem that lets them measure how similar these unknowns are to known natural product molecules so that they can add this factor to a better ranking of the correct structures in the results list for screening and further investigation.

Read More thumbnail image: Its only natural Metabolomics plugin

Fair-weather power: Solar textiles

Date: Aug 15, 2014

Author: David Bradley

Whether you're a tweed-wearing hipster or down with the kids sporting your post-modern baggy jeans, textile-based solar cells that could be patched into your clothes might one day let you charge up your mobile phone or other gadgets while out in the sunshine, according to research published this month in the journal Angewandte Chemie. The work by scientists in China used X-ray characterization of key components to take the first solar strides.

Read More thumbnail image: Fair-weather power Solar textiles

Chemical rewiring: Nerve growth

Date: Aug 15, 2014

Author: David Bradley

New research from and international team using NMR spectroscopy suggests that a single, small molecule might be able to persuade nerves damaged by injury to grow new connections, offering a future hope for people who suffer spinal injuries and paralysis.

Read More thumbnail image: Chemical rewiring Nerve growth
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