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Journal Highlight: Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes

Date: Jul 24, 2017

Author: spectroscopyNOW

The most comprehensive and accurate human protein complex map to date, hu.MAP has been derived from > 9,000 published mass spectrometry experiments to hold > 4,600 total complexes, > 7,700 proteins, and > 56,000 unique interactions, including many not identified by the original publications.

Read More thumbnail image: Journal Highlight Integration of over 9000 mass spectrometry experiments builds a global map of human protein complexes

Journal Highlight: Fetal brain injury in complicated monochorionic pregnancies: diagnostic yield of prenatal MRI following surveillance ultrasound and influence on prognostic counselling

Date: Jul 24, 2017

Author: spectroscopyNOW

Additional diagnostic information provided by prenatal (fetal) pMRI following tertiary ultrasound for fetal cranial abnormalities in complicated monochorionic gestations can lead to changed prognostic counselling.

Read More thumbnail image: Journal Highlight Fetal brain injury in complicated monochorionic pregnancies diagnostic yield of prenatal MRI following surveillance ultrasound and influence on prognostic counselling

Journal Highlight: Determination of cannabinoids in hemp nut products in Taiwan by HPLC-MS/MS coupled with chemometric analysis: quality evaluation and a pilot human study

Date: Jul 17, 2017

Author: spectroscopyNOW

The Δ9-tetrahydrocannabinol, cannabidiol and cannabinol contents of concentrated hemp powdered nut products were determined by LC/MS using hierarchical clustering analysis and principal component analysis.

Read More thumbnail image: Journal Highlight Determination of cannabinoids in hemp nut products in Taiwan by HPLC-MSMS coupled with chemometric analysis quality evaluation and a pilot human study

Extended beer proteome: Allergenic gluten proteins

Date: Jul 15, 2017

Author: Steve Down

The most extensive proteome of lager beer to date has been been derived by scientists in the Czech Republic who made a special effort to identify gluten proteins which might be allergenic.

Read More thumbnail image: Extended beer proteome Allergenic gluten proteins

Canine explosives detection: Complementary vapour analysis improves training

Date: Jul 15, 2017

Author: Steve Down

A mass spectrometer has been developed by scientists at MIT to measure explosive vapours in real time to assist training sniffer dogs in the field and develop better training materials.

Read More thumbnail image: Canine explosives detection Complementary vapour analysis improves training

Weighing up ways of working out log P

Date: Jul 15, 2017

Author: Ryan De Vooght-Johnson

Lipophilicity is a key parameter affecting the activity of potential drug molecules, but there are many methods to calculate it. Scientists from the University of Belgrade examined various techniques for calculating the lipophilicity of a number of benzothiepino[3,2-c]pyridine derivatives, which were potential antifungal drugs.

Read More thumbnail image: Weighing up ways of working out log P

Phosphorus rubber: Multinuclear NMR

Date: Jul 15, 2017

Author: David Bradley

Poly-(1-phospha-isoprene) is a phosphorus-containing analogue of natural rubber that might find applications in creating macromolecular gold complexes for use in nanotechnology. 31P{1H} nuclear magnetic resonance (NMR) spectroscopy was used to provide a preliminary structure of the compound.

Read More thumbnail image: Phosphorus rubber Multinuclear NMR

Maltol assessed: Toxic enhancer determined by FAAS

Date: Jul 15, 2017

Author: David Bradley

Simple ultrasound extraction followed by flame atomic absorption spectrometry (FAAS) of food samples can be used to quickly determine concentrations of the potentially toxic flavour enhancer maltol.

Read More thumbnail image: Maltol assessed Toxic enhancer determined by FAAS

Ad hoc landfill: PARAFAC of pollution risk

Date: Jul 15, 2017

Author: David Bradley

Simple landfills in developing countries represent a threat to soil and groundwater through toxic leachate. Soil column experiments to simulate pollution have been assessed using PARAFAC modelling of three-dimensional excitation-emission fluorescence to evaluate the specific risks.

Read More thumbnail image: Ad hoc landfill PARAFAC of pollution risk

Tiniest cubic ice crystals: X-rayed

Date: Jul 15, 2017

Author: David Bradley

A new X-ray study of the tiny, almost perfect square ice crystals predicted to form in the chilly realm of high altitude clouds but extremely difficult to make at ground level could open up studies on how sunlight and air interact with clouds thereby improving our models of climate change.

Read More thumbnail image: Tiniest cubic ice crystals X-rayed
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