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Journal Highlight: The effects of ageing on mouse muscle microstructure: A comparative study of time-dependent diffusion MRI and histological assessment

Date: Feb 19, 2018

Author: spectroscopyNOW

The evolution of mouse hind-limb muscle microstructure using diffusion imaging of actively growing and mature mice has been studied to shed light on the clinical features of early-onset muscle diseases, such as Duchenne muscular dystrophy.

Read More thumbnail image: Journal Highlight The effects of ageing on mouse muscle microstructure A comparative study of time-dependent diffusion MRI and histological assessment

Journal Highlight: The human protein atlas: A spatial map of the human proteome

Date: Feb 19, 2018

Author: spectroscopyNOW

The Human Protein Atlas database functions and the ways that users can utilize them for their own research have been comprehensively described, along with the future path of spatial proteomics.

Read More thumbnail image: Journal Highlight The human protein atlas A spatial map of the human proteome

Canine saliva: Inter-breed proteomics

Date: Feb 15, 2018

Author: Steve Down

The proteome of dog saliva differs between breeds and between individual animals of the same breed, say scientists in the UK, who compared differently sized breeds for the first time.

Read More thumbnail image: Canine saliva Inter-breed proteomics

Tainted toys: Portable testing with ambient ionisation

Date: Feb 15, 2018

Author: Steve Down

Three ambient ionisation techniques have been coupled with a miniature mass spectrometer for the analysis of regulated compounds in toys, providing a rapid and sensitive method to rival traditional methods that could be taken into the field.

Read More thumbnail image: Tainted toys Portable testing with ambient ionisation

Polarity parameters put in place by QSPR

Date: Feb 15, 2018

Author: Ryan De Vooght-Johnson

Computational prediction of relative retention times for HPLC can, in theory, save the running of numerous trials when developing new methods. Scientists from the Islamic Azad University in Tehran, looked at the prediction of solute polarity parameters, which can be used to calculate retention times, using a support vector machine technique and an enhanced replacement method.

Read More thumbnail image: Polarity parameters put in place by QSPR

Magnetic benchmark: Record-breaking thin film

Date: Feb 15, 2018

Author: David Bradley

US researchers have developed a new magnetic thin film that could finally break through the Slater-Pauling limit on magnetic density in a material. With this decades-old benchmark circumvented new applications and devices might be possible.

Read More thumbnail image: Magnetic benchmark Record-breaking thin film

The trouble with mass: Multivariate metabolism

Date: Feb 15, 2018

Author: David Bradley

A new analytical approach to the data by a team from Spain and the UK might have solved the riddle of why the bigger an animal is the lower its basal metabolic rate, the minimum energy used to stay alive.

Read More thumbnail image: The trouble with mass Multivariate metabolism

Cancer enzyme targets: Neutrons and glaucoma drug

Date: Feb 15, 2018

Author: David Bradley

A neutron crystallographic analysis of various drugs used to treat the eye condition glaucoma and their enzyme target could point the way to novel pharmaceuticals for targeting aggressive cancers more effectively because of a link with human carbonic anhydrases (hCAs).

Read More thumbnail image: Cancer enzyme targets Neutrons and glaucoma drug

Heavy metal drugs: Atomic answers

Date: Feb 15, 2018

Author: David Bradley

Axial viewed inductively coupled plasma atomic emission spectrometry with ultrasonic nebulization has been used to determination concentrations of various metallic and other elemental impurities in oral pharmaceutical products.

Read More thumbnail image: Heavy metal drugs Atomic answers

Journal Highlight: Source determination of red gel pen inks using Raman spectroscopy and ATR-FTIR spectroscopy combined with Pearson's product moment correlation coefficients and principal component analysis

Date: Feb 12, 2018

Author: spectroscopyNOW

The potential combination of Raman spectroscopy and ATR-FTIR spectroscopy with Pearson's product moment correlation coefficients and PCA has been examined to determine the actual source of red gel pen ink used to write a simulated threatening note.

Read More thumbnail image: Journal Highlight Source determination of red gel pen inks using Raman spectroscopy and ATR-FTIR spectroscopy combined with Pearsons product moment correlation coefficients and principal component analysis
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