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Journal Highlight: Liver histology and diffusion-weighted MRI in children with nonalcoholic fatty liver disease: A MAGNET study

Date: Oct 16, 2017

Author: spectroscopyNOW

Potential associations between histologic features of pediatric nonalcoholic fatty liver disease and estimated quantitative magnetic resonance diffusion-weighted imaging (DWI) parameters have been explored.

Read More thumbnail image: Journal Highlight Liver histology and diffusion-weighted MRI in children with nonalcoholic fatty liver disease A MAGNET study

Influenza A proteins: Individual proteome variations

Date: Oct 15, 2017

Author: Steve Down

Scientists in the US have shown that the proteomes of normal human bronchial epithelial cells are unique for individual people and also respond to infection by the influenza A virus in different ways, findings which could be used to identify people more susceptible to the disease.

Read More thumbnail image: Influenza A proteins Individual proteome variations

New building air quality: Pinpointing flame retardant sources

Date: Oct 15, 2017

Author: Steve Down

Flame retardants and other semivolatile organic compounds have been measured in the air inside four different room types in a newly constructed building to identify their potential sources and track their levels over the first year of occupation.

Read More thumbnail image: New building air quality Pinpointing flame retardant sources

Small peaks are amplified when stochastic noise is applied

Date: Oct 15, 2017

Author: Ryan De Vooght-Johnson

Small chromatographic peaks that are hidden by baseline noise can be made clearer by employing stochastic resonance, which involves the addition of a limited amount of additional noise. Researchers from China Pharmaceutical University in Nanjing, Nanjing University of Chinese Medicine and Nanjing Changao Pharmaceutical Technology have reported an improved algorithm for the amplification of peaks using stochastic resonance, demonstrating its use with two different examples.

Read More thumbnail image: Small peaks are amplified when stochastic noise is applied

Cool microscopy: Nobel chemistry

Date: Oct 15, 2017

Author: David Bradley

The development of cryo-electron microscopy has led to this year's Nobel Prize for Chemistry been awarded to Jacques Dubochet of the University of Lausanne, Switzerland, Joachim Frank of Columbia University, New York, USA, and Richard Henderson of the Medical research Council Laboratory of Molecular Biology (MRC-LMB) in Cambridge, UK.

Read More thumbnail image: Cool microscopy Nobel chemistry

Metals in meat: Bioavailability assessed by spectroscopy

Date: Oct 15, 2017

Author: David Bradley

Various techniques including graphite furnace atomic absorption spectrometry have been used to assess the bioavailability of metals ions present in beef, pork, and chicken after thermal treatment. The study shows that high temperatures make nutrient metal ions of calcium, copper, iron, magnesium and zinc less readily available.

Read More thumbnail image: Metals in meat Bioavailability assessed by spectroscopy

Spot the difference: NMR technique for drug design

Date: Oct 15, 2017

Author: David Bradley

A powerful new NMR technique DiffErential EPitope mapping by STD NMR spectroscopy (DEEP-STD NMR) is being used by researchers in the UK to reveal the nature of the contact between ligand and protein target with a view to developing new pharmaceuticals with fewer side-effects.

Read More thumbnail image: Spot the difference NMR technique for drug design

Better bread and beer: Chemometric bakeoff

Date: Oct 15, 2017

Author: David Bradley

The use of multivariate data has allowed researchers from the Department of Food Science (FOOD) at the University of Copenhagen in Denmark to build a regression model of the analysis of whole grains at long near-infrared (NIR) wavelengths obtained with a supercontinuum laser. The research could improve our understanding of the chemistry of food ingredients with implications for improving bread and beer.

Read More thumbnail image: Better bread and beer Chemometric bakeoff

Virtual Issue - 2017 Nobel Prize in Chemistry Winners

Date: Oct 9, 2017

Author:

The 2017 Nobel Prize in Chemistry has been awarded to Professor Jacques Dubochet, Dr Joachim Frank and Dr Richard Henderson for the development of cryo-electron microscopy for imaging of biomolecules in solution. To celebrate the Award, we present here articles by Professor Dubochet and Dr Frank published in the Journal of Microscopy.

Read More thumbnail image: Virtual Issue - 2017 Nobel Prize in Chemistry Winners

Journal Highlight: Mining molecular structure databases: Identification of small molecules based on fragmentation mass spectrometry data

Date: Oct 9, 2017

Author: spectroscopyNOW

Computational methods that help with the identification of small molecules by analyzing mass spectral fragmentation data have been reviewed, focusing on the four main approaches to mine a database.

Read More thumbnail image: Journal Highlight Mining molecular structure databases Identification of small molecules based on fragmentation mass spectrometry data
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