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Journal Highlight: Identification of unique proteomic signatures in allergic and non-allergic skin disease

Date: Aug 21, 2017

Author: spectroscopyNOW

Unique proteomic signatures have been identified to distinguish between inflammatory diseases with similar epidermal disruption and overlapping epithelial inflammation.

Read More thumbnail image: Journal Highlight Identification of unique proteomic signatures in allergic and non-allergic skin disease

Dominant or submissive: Proteomic clues to behavioural disorders

Date: Aug 15, 2017

Author: Steve Down

The expression of many proteins in the hippocampi of mice are modified by dominant and submissive behaviour, say scientists in Israel in the first study of its kind which will help to decode the molecular mechanisms of psychiatric disorders and lead to therapeutic solutions.

Read More thumbnail image: Dominant or submissive Proteomic clues to behavioural disorders

Exhaled breath: Doping control option

Date: Aug 15, 2017

Author: Steve Down

In a proof-of-concept study, German scientists have shown that exhaled breath can be used as a novel sampling medium by sports testing organisations for doping control, paving the way for another mode of noninvasive testing.

Read More thumbnail image: Exhaled breath Doping control option

No standards involved, but are all problems solved?

Date: Aug 15, 2017

Author: Ryan De Vooght-Johnson

Modern analytical techniques, such as HRMS (high-resolution mass spectrometry), enable the simultaneous detection of a large number of compounds, but normally rely on analytical standards of all the compounds being available, which may not be the case. Researchers from the Zurich Official Food Control Authority have developed an LC-HRMS method that identifies compounds without the use of standards, demonstrating its efficiency by identifying veterinary compounds spiked into meat and fish extracts.

Read More thumbnail image: No standards involved but are all problems solved

Date rape drug metabolite: NMR reveals evidence next day

Date: Aug 15, 2017

Author: David Bradley

Nuclear magnetic resonance (NMR) spectroscopy can be used to quickly identify a biomarker for the presence of gamma-hydroxybutyric acid (GHB, the so-called "date rape" drug) in a biological sample from a putative victim of crime. Details are reported in the American Chemical Society's journal Analytical Chemistry.

Read More thumbnail image: Date rape drug metabolite NMR reveals evidence next day

Plasma toughens nanotubes: Computer simulation

Date: Aug 15, 2017

Author: David Bradley

A computer simulation by US scientists reveals how a high-energy plasma can be used to toughen up carbon nanotubes.

Read More thumbnail image: Plasma toughens nanotubes Computer simulation

Gold too? Ions in the +II oxidation state

Date: Aug 15, 2017

Author: David Bradley

When it comes to atoms there are several seemingly immutable facts about many of them - their oxidation states or valencies are seemingly fixed. However, whereas gold is generally considered to exist as only gold(I) and gold(III), theoretically, a 2+ oxidation state should exist to fill the gap in the homologous series of the coinage metal ions copper(+II), silver(+II), gold(+II), and in the "relativistic" triad of platinum(+II), gold(+II), and mercury(+II). That gap has now been filled as chemists isolate...

Read More thumbnail image: Gold too Ions in the II oxidation state

DNA unravelled: X-rays show archaic folding origin

Date: Aug 15, 2017

Author: David Bradley

New X-ray crystallographic work by scientists at the Howard Hughes Medical Institute reveals that organisms with cell nuclei, eukaryotes, which includes all multicellular life uses proteins to pack its DNA into the cell nucleus using similar folding techniques as that seen in microbes whose ancestry stretches back to the dawn of life on earth, the archaea.

Read More thumbnail image: DNA unravelled X-rays show archaic folding origin

Journal Highlight: Elimination of matrix interferences in GC-MS analysis of pesticides by entropy minimization

Date: Aug 14, 2017

Author: spectroscopyNOW

An entropy minimization technique that can eliminate the need for comprehensive preprocessing steps has been developed to detect organophosphorus pesticides in a fortified orange juice sample by GC/MS.

Read More thumbnail image: Journal Highlight Elimination of matrix interferences in GC-MS analysis of pesticides by entropy minimization

Journal Highlight: Raman study of graphene nanoribbon analogs confined in single-walled carbon nanotubes and their high-pressure transformations

Date: Aug 10, 2017

Author: spectroscopyNOW

High-pressure transformation of single wall carbon nanotubes filled with perylene molecules that form short-chain nanoribbon analogs inside the tubes has been studied by Raman spectroscopy combined with theoretical simulation.

Read More thumbnail image: Journal Highlight Raman study of graphene nanoribbon analogs confined in single-walled carbon nanotubes and their high-pressure transformations
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