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Lip up: Fatty molecules investigated

Date: Jul 1, 2013

Author: David Bradley

Fatty lipid molecules in the human body act not only as energy storage molecules and structural elements but are also important signalling compounds. Lipids with their head in a molecular cage have now been used to study such molecules and their roles in diseases such as atherosclerosis and diabetes.

Read More thumbnail image: Lip up Fatty molecules investigated

Back to basics: MRI reveals spinal infection

Date: Jul 1, 2013

Author: David Bradley

Steroids are often injected into sites along the spinal column in treating back pain, but if a batch is contaminated serious infection can arise. Researchers have demonstrated that magnetic resonance imaging (MRI) at the site of injection could be used to identify fungal spinal or paraspinal infection

Read More thumbnail image: Back to basics MRI reveals spinal infection

Satisfying your curiosity: The bigger picture

Date: Jul 1, 2013

Author: David Bradley

Images recorded by NASA's Curiosity Mars rover and sent back to Earth have been composited into what is the equivalent of a 1000 megapixel photograph of the surface of the Red Planet.

Read More thumbnail image: Satisfying your curiosity The bigger picture

Fuel matters: Insights into enzymatic conversion

Date: Jul 1, 2013

Author: David Bradley

Altering the crystalline structure of cellulose from its native form to another can lower its binding partition coefficient for fungal cellulose enzymes by 40-50 percent but surprisingly boost hydrolytic activity. This new finding could thus help open the road to more efficient enzymatic production of biofuels from biomass rather than petroleum.

Read More thumbnail image: Fuel matters Insights into enzymatic conversion

Vendor Column: Uses for Scientific Search

Date: Jun 26, 2013

Author: Chris Stumpf

In this third article in the latest series, Waters Corporation's Chris Stumpf looks at several analytical chemistry-based roles where Scientific Search could have a measureable impact at science focused organizations.

Read More thumbnail image: Vendor Column Uses for Scientific Search

Journal Highlight: Tissue proteomics of the low-molecular weight proteome using an integrated cLC-ESI-QTOFMS approach

Date: Jun 24, 2013

Author: spectroscopyNOW

A tissue proteomics approach involving tissue homogenization followed by depletion of large proteins and then capillary LC-MS analysis has been evaluated for examining the low molecular weight/low abundance tissue proteome.

Read More thumbnail image: Journal Highlight Tissue proteomics of the low-molecular weight proteome using an integrated cLC-ESI-QTOFMS approach

Journal Highlight: DCE-MRI: a review and applications in veterinary oncology

Date: Jun 24, 2013

Author: spectroscopyNOW

This review summarises the derivation of the models developed to assess dynamic contrast enhanced magnetic resonance imaging (DCE-MRI), its applications to the study and treatment of human and animal cancer, and challenges in reproducibility.

Read More thumbnail image: Journal Highlight DCE-MRI a review and applications in veterinary oncology

Journal Highlight: Core consistency diagnostic in PARAFAC2

Date: Jun 17, 2013

Author: spectroscopyNOW

The possibility of applying the core consistency diagnostic which is currently applied in PARAFAC1 to determine model complexity in PARAFAC2 has been investigated theoretically.

Read More thumbnail image: Journal Highlight Core consistency diagnostic in PARAFAC2

Microbore protein digestor: Hollow fibre reactor for online proteolysis

Date: Jun 15, 2013

Author: Steve Down

A microbore enzyme reactor constructed from a hollow fibre that is linked directly to an LC/MS system has been designed for the online digestion, purification and analysis of low amounts of proteins.

Read More thumbnail image: Microbore protein digestor Hollow fibre reactor for online proteolysis

Sudan dyes in seconds: Paper spray mass spectrometry for chilli powder tests

Date: Jun 15, 2013

Author: Steve Down

Paper spray mass spectrometry has been applied to measure five Sudan dyes simultaneously in chilli pepper within 60 seconds, providing a green, high-throughput method that could be used in quality control labs.

Read More thumbnail image: Sudan dyes in seconds Paper spray mass spectrometry for chilli powder tests
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