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Mouthwash: An anticancer solution

Date: Apr 1, 2013

Author: David Bradley

The active ingredients in some commercially available mouthwash solution, the bisbiguanide oral disinfectants chlorhexidine (Chlorhexamed, Chlorhexal, Periogard, Corsodyl, and Chlorohex) and alexidine (Esemdent) have been in widespread use for many years. Now, 1H,15N-HSQC NMR spectroscopy has been used in studies to investigate the structural changes these compounds can induce that lead to apoptosis in oral cancer cells.

Read More thumbnail image: Mouthwash An anticancer solution

Gut instinct: Stem cell reactions

Date: Apr 1, 2013

Author: David Bradley

In research funded by Great Ormond Street Hospital Children's Charity and with support from the Fondazione Citta della Speranza, researchers have demonstrated that stem cells taken from amniotic fluid can be used to restore gut structure and function following intestinal damage in rodents. The new work published in the journal Gut uses magnetic resonance imaging and could pave the way to a new form of cell therapy that is able to reverse serious damage caused by inflammation in the intestines of babies.

Read More thumbnail image: Gut instinct Stem cell reactions

Paintable electronics: Bringing polymers into line

Date: Apr 1, 2013

Author: David Bradley

Engineers at the University of Michigan and electronics company Samsung in Korea have devised a method for bringing otherwise unruly semiconducting polymers into line as verified by X-ray diffraction studies, which they suggest might one day pave the way for cheaper, greener, "paint-on" plastic electronics.

Read More thumbnail image: Paintable electronics Bringing polymers into line

Chlorophyll f: UV sheds some light on infrared molecule

Date: Apr 1, 2013

Author: David Bradley

Chlorophyll f is the most red-shifted natural chlorophyll and is made by the blue-green alga Halomicronema hongdechloris. Researchers have now carried out a structural assignment UV-Vis spectroscopy and other techniques. New insights into chlorophyll and its variants is important for understanding photosynthesis as well as for research into energy conversion, electron transfer applications.

Read More thumbnail image: Chlorophyll f UV sheds some light on infrared molecule

Journal Highlight: Mass spectrometry-based proteomics: The road to lung cancer biomarker discovery

Date: Mar 24, 2013

Author: spectroscopyNOW

This review describes studies that use mass spectrometry-based proteomics technologies to analyse tumour proteins and peptides which might represent new diagnostic, prognostic and predictive markers for lung cancer.

Read More thumbnail image: Journal Highlight Mass spectrometry-based proteomics The road to lung cancer biomarker discovery

Journal Highlight: High-resolution MRI of early-stage mouse embryos

Date: Mar 24, 2013

Author: spectroscopyNOW

A method of imaging the mouse embryo from the early stages close to the onset of organogenesis uses a self-gated MRI protocol combined with image registration to obtain whole-embryo high-resolution 3D images.

Read More thumbnail image: Journal Highlight High-resolution MRI of early-stage mouse embryos

Journal Highlight: Detection of low-quality extra virgin olive oils by fatty acid alkyl esters evaluation: a preliminary and fast mid-IR spectroscopy discrimination by a chemometric approach

Date: Mar 18, 2013

Author: spectroscopyNOW

FT mid-IR spectroscopy with partial least squares analysis was used to predict the contents of fatty acid methyl and ethyl esters in extra virgin olive oils, allowing low-quality products to be identified.

Read More thumbnail image: Journal Highlight Detection of low-quality extra virgin olive oils by fatty acid alkyl esters evaluation a preliminary and fast mid-IR spectroscopy discrimination by a chemometric approach

Clearing the airways: Distinguishing smoking-related diseases by NMR

Date: Mar 15, 2013

Author: Steve Down

NMR spectroscopy of the metabolites in exhaled breath condensate can distinguish between airway respiratory diseases induced by smoking, say Italian researchers.

Read More thumbnail image: Clearing the airways Distinguishing smoking-related diseases by NMR

Keeping your nerve: VX in drinking water

Date: Mar 15, 2013

Author: Steve Down

The nerve agent VX has been determined in drinking water by a high-throughput LC/MS method combined with special treatment to prevent it from decomposing before analysis.

Read More thumbnail image: Keeping your nerve VX in drinking water

Carbon capture: Porous trap for greenhouse gas

Date: Mar 15, 2013

Author: David Bradley

Scientists at the King Abdullah University of Science and Technology (KAUST) and the University of South Florida (USF), USA, have developed a unique, efficient, cost-effective as well reusable metal-organic framework (MOF) material, for trapping and separating carbon dioxide from various gas streams. These crystalline materials could lead to clean-air and energy-saving technologies.

Read More thumbnail image: Carbon capture Porous trap for greenhouse gas
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