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Journal Highlight: Mid-infrared (IR) – A hot topic: The potential for using mid-IR light for non-invasive early detection of skin cancer in vivo

Date: Jun 3, 2013

Author: spectroscopyNOW

The remarkable progress made towards mid-IR spectral in vitro mapping of tissue and cancer detection is reviewed and the status quo of chalcogenide glass mid-IR fibre optics and photonics for remote mid-IR sensing in general, and in vivo cancer detection in particular, is assessed.

Read More thumbnail image: Journal Highlight Mid-infrared IR  A hot topic The potential for using mid-IR light for non-invasive early detection of skin cancer in vivo

Filter paper prop: Support for biological samples in well plates for forensic drug analysis

Date: Jun 1, 2013

Author: Steve Down

Filter paper has been used as a support in 96-well plates for ten types of biological fluids and tissues in the post-mortem LC/MS analysis of the alkaloid colchicine, in which the calibration curve for dried blood spots can be applied to most of the other sample types.

Read More thumbnail image: Filter paper prop Support for biological samples in well plates for forensic drug analysis

Pancreatic poser: Interspecies effects of nicotine on proteome

Date: Jun 1, 2013

Author: Steve Down

Nicotine affects pancreatic stellate cells from different species in similar ways, suggesting common interaction pathways that will help to understand the link between smoking and pancreatic disease, say researchers in the US.

Read More thumbnail image: Pancreatic poser Interspecies effects of nicotine on proteome

Colours to dye for: Spray on pigments

Date: Jun 1, 2013

Author: David Bradley

Japanese scientists have developed a new type of colouring agent that is not only environmentally friendly but does not fade like conventional textile dyes and pigments. The colourants consist of submicrometre-sized silicon dioxide particles and carbon black and can be sprayed on to the desired surface to generate bright colours that are permanent and highly fade resistant.

Read More thumbnail image: Colours to dye for Spray on pigments

Diffract and destroy: Fluctuation X-ray scattering

Date: Jun 1, 2013

Author: David Bradley

Fluctuation X-ray scattering could help fill the gaps in our knowledge of protein structure thanks to the short bursts of radiation allowing data to be obtained from non-crystallisable proteins in their native, fluid state albeit with the sacrifice of the protein itself.

Read More thumbnail image: Diffract and destroy Fluctuation X-ray scattering

Total emissions: Adding up all the light

Date: Jun 1, 2013

Author: David Bradley

How much light has been emitted by all the galaxies across the universe since the Big Bang? It is a fundamental question, poignant given that almost every photon ever emitted whether in the ultraviolet to far infrared wavelengths in the electromagnetic spectrum are still wending their way across the cosmos to this day with relatively few stopped in their tracks by matter.

Read More thumbnail image: Total emissions Adding up all the light

Algorithmic Raman: Improved breast diagnostics

Date: Jun 1, 2013

Author: David Bradley

A newly developed, single-step algorithm for processing Raman spectra can reveal the presence of microcalcifications in breast tissue that are often associated with breast cancer lesions and so improve the precision of diagnosis of the disease itself at the early stages without multiple biopsies of suspicious lumps.

Read More thumbnail image: Algorithmic Raman Improved breast diagnostics

Handheld cancer detection: Microfluidics meets NMR

Date: Jun 1, 2013

Author: David Bradley

A handheld device first developed for cancer diagnosis has been adapted to rapidly diagnose tuberculosis (TB) and other bacterial infections. Two papers appearing in the journals Nature Communications and Nature Nanotechnology describe the portable systems that bring together microfluidics technology and NMR.

Read More thumbnail image: Handheld cancer detection Microfluidics meets NMR

Aging enzyme: MRI reveals depressing link

Date: Jun 1, 2013

Author: David Bradley

Magnetic resonance imaging has revealed a possible protective role for the enzyme telomerase in processes associated with the development of depression in aging patients. The study investigated untreated, depressed participants and found that the size of the hippocampus, a brain structure that is critical for learning and memory, was associated with the amount of telomerase activity measured in the white blood cells.

Read More thumbnail image: Aging enzyme MRI reveals depressing link

Journal Highlight: Proteomics applied to transfusion plasma: the beginning of the story

Date: May 20, 2013

Author: spectroscopyNOW

The principles of proteomics analysis and the state of the art applied to plasma analysis are presented, along with the use of proteomics for assessing the impact of storage conditions and pathogen inactivation treatments on transfusion plasma.

Read More thumbnail image: Journal Highlight Proteomics applied to transfusion plasma the beginning of the story
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