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- Review and analysis articles written by our team of renowned contributors.
- Free access to journal articles on Wiley Online Library, selected by the website editor.
- "Client Column" articles written by experts from spectroscopy and separation science industrial companies.
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rssJournal Highlight: Mid-infrared (IR) – A hot topic: The potential for using mid-IR light for non-invasive early detection of skin cancer in vivo
Date: Jun 3, 2013
Author: spectroscopyNOW
The remarkable progress made towards mid-IR spectral in vitro mapping of tissue and cancer detection is reviewed and the status quo of chalcogenide glass mid-IR fibre optics and photonics for remote mid-IR sensing in general, and in vivo cancer detection in particular, is assessed.
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Filter paper prop: Support for biological samples in well plates for forensic drug analysis
Date: Jun 1, 2013
Author: Steve Down
Filter paper has been used as a support in 96-well plates for ten types of biological fluids and tissues in the post-mortem LC/MS analysis of the alkaloid colchicine, in which the calibration curve for dried blood spots can be applied to most of the other sample types.
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Pancreatic poser: Interspecies effects of nicotine on proteome
Date: Jun 1, 2013
Author: Steve Down
Nicotine affects pancreatic stellate cells from different species in similar ways, suggesting common interaction pathways that will help to understand the link between smoking and pancreatic disease, say researchers in the US.
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Colours to dye for: Spray on pigments
Date: Jun 1, 2013
Author: David Bradley
Japanese scientists have developed a new type of colouring agent that is not only environmentally friendly but does not fade like conventional textile dyes and pigments. The colourants consist of submicrometre-sized silicon dioxide particles and carbon black and can be sprayed on to the desired surface to generate bright colours that are permanent and highly fade resistant.
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Diffract and destroy: Fluctuation X-ray scattering
Date: Jun 1, 2013
Author: David Bradley
Fluctuation X-ray scattering could help fill the gaps in our knowledge of protein structure thanks to the short bursts of radiation allowing data to be obtained from non-crystallisable proteins in their native, fluid state albeit with the sacrifice of the protein itself.
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Total emissions: Adding up all the light
Date: Jun 1, 2013
Author: David Bradley
How much light has been emitted by all the galaxies across the universe since the Big Bang? It is a fundamental question, poignant given that almost every photon ever emitted whether in the ultraviolet to far infrared wavelengths in the electromagnetic spectrum are still wending their way across the cosmos to this day with relatively few stopped in their tracks by matter.
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Algorithmic Raman: Improved breast diagnostics
Date: Jun 1, 2013
Author: David Bradley
A newly developed, single-step algorithm for processing Raman spectra can reveal the presence of microcalcifications in breast tissue that are often associated with breast cancer lesions and so improve the precision of diagnosis of the disease itself at the early stages without multiple biopsies of suspicious lumps.
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Handheld cancer detection: Microfluidics meets NMR
Date: Jun 1, 2013
Author: David Bradley
A handheld device first developed for cancer diagnosis has been adapted to rapidly diagnose tuberculosis (TB) and other bacterial infections. Two papers appearing in the journals Nature Communications and Nature Nanotechnology describe the portable systems that bring together microfluidics technology and NMR.
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Aging enzyme: MRI reveals depressing link
Date: Jun 1, 2013
Author: David Bradley
Magnetic resonance imaging has revealed a possible protective role for the enzyme telomerase in processes associated with the development of depression in aging patients. The study investigated untreated, depressed participants and found that the size of the hippocampus, a brain structure that is critical for learning and memory, was associated with the amount of telomerase activity measured in the white blood cells.
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Journal Highlight: Proteomics applied to transfusion plasma: the beginning of the story
Date: May 20, 2013
Author: spectroscopyNOW
The principles of proteomics analysis and the state of the art applied to plasma analysis are presented, along with the use of proteomics for assessing the impact of storage conditions and pathogen inactivation treatments on transfusion plasma.
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