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rssMouthwash: An anticancer solution
Date: Apr 1, 2013
Author: David Bradley
The active ingredients in some commercially available mouthwash solution, the bisbiguanide oral disinfectants chlorhexidine (Chlorhexamed, Chlorhexal, Periogard, Corsodyl, and Chlorohex) and alexidine (Esemdent) have been in widespread use for many years. Now, 1H,15N-HSQC NMR spectroscopy has been used in studies to investigate the structural changes these compounds can induce that lead to apoptosis in oral cancer cells.
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Gut instinct: Stem cell reactions
Date: Apr 1, 2013
Author: David Bradley
In research funded by Great Ormond Street Hospital Children's Charity and with support from the Fondazione Citta della Speranza, researchers have demonstrated that stem cells taken from amniotic fluid can be used to restore gut structure and function following intestinal damage in rodents. The new work published in the journal Gut uses magnetic resonance imaging and could pave the way to a new form of cell therapy that is able to reverse serious damage caused by inflammation in the intestines of babies.
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Paintable electronics: Bringing polymers into line
Date: Apr 1, 2013
Author: David Bradley
Engineers at the University of Michigan and electronics company Samsung in Korea have devised a method for bringing otherwise unruly semiconducting polymers into line as verified by X-ray diffraction studies, which they suggest might one day pave the way for cheaper, greener, "paint-on" plastic electronics.
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Chlorophyll f: UV sheds some light on infrared molecule
Date: Apr 1, 2013
Author: David Bradley
Chlorophyll f is the most red-shifted natural chlorophyll and is made by the blue-green alga Halomicronema hongdechloris. Researchers have now carried out a structural assignment UV-Vis spectroscopy and other techniques. New insights into chlorophyll and its variants is important for understanding photosynthesis as well as for research into energy conversion, electron transfer applications.
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Journal Highlight: Mass spectrometry-based proteomics: The road to lung cancer biomarker discovery
Date: Mar 24, 2013
Author: spectroscopyNOW
This review describes studies that use mass spectrometry-based proteomics technologies to analyse tumour proteins and peptides which might represent new diagnostic, prognostic and predictive markers for lung cancer.
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Journal Highlight: High-resolution MRI of early-stage mouse embryos
Date: Mar 24, 2013
Author: spectroscopyNOW
A method of imaging the mouse embryo from the early stages close to the onset of organogenesis uses a self-gated MRI protocol combined with image registration to obtain whole-embryo high-resolution 3D images.
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Journal Highlight: Detection of low-quality extra virgin olive oils by fatty acid alkyl esters evaluation: a preliminary and fast mid-IR spectroscopy discrimination by a chemometric approach
Date: Mar 18, 2013
Author: spectroscopyNOW
FT mid-IR spectroscopy with partial least squares analysis was used to predict the contents of fatty acid methyl and ethyl esters in extra virgin olive oils, allowing low-quality products to be identified.
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Clearing the airways: Distinguishing smoking-related diseases by NMR
Date: Mar 15, 2013
Author: Steve Down
NMR spectroscopy of the metabolites in exhaled breath condensate can distinguish between airway respiratory diseases induced by smoking, say Italian researchers.
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Keeping your nerve: VX in drinking water
Date: Mar 15, 2013
Author: Steve Down
The nerve agent VX has been determined in drinking water by a high-throughput LC/MS method combined with special treatment to prevent it from decomposing before analysis.
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Carbon capture: Porous trap for greenhouse gas
Date: Mar 15, 2013
Author: David Bradley
Scientists at the King Abdullah University of Science and Technology (KAUST) and the University of South Florida (USF), USA, have developed a unique, efficient, cost-effective as well reusable metal-organic framework (MOF) material, for trapping and separating carbon dioxide from various gas streams. These crystalline materials could lead to clean-air and energy-saving technologies.
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