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Journal Highlight: Resonance Raman of oxygen dangling bonds in amorphous silicon dioxide

Date: Mar 6, 2017

Author: spectroscopyNOW

A resonance Raman band induced by ionizing radiation in amorphous silicon dioxide, which can be detected under ultraviolet laser excitation, has been assigned to oxygen dangling bonds.

Read More thumbnail image: Journal Highlight Resonance Raman of oxygen dangling bonds in amorphous silicon dioxide

Saliva for disease biomarkers: Gender and acid stimulation effects

Date: Mar 1, 2017

Author: Steve Down

A more complete understanding of the effects of gender and acid simulation on the saliva proteome has been provided by scientists in China to help support the search for disease-specific biomarkers.

Read More thumbnail image: Saliva for disease biomarkers Gender and acid stimulation effects

Processed meat authenticity: Beef vs. pork in Bolognese sauce

Date: Mar 1, 2017

Author: Steve Down

The content of beef and pork in a true Bolognese sauce has been measured using unique peptides derived from the collagen of each species, allowing the authenticity of meat products to be confirmed and food fraud detected.

Read More thumbnail image: Processed meat authenticity Beef vs_ pork in Bolognese sauce

Mercury lights up swordfish: UV fluorophore

Date: Mar 1, 2017

Author: David Bradley

A fluorescent polymer that lights up when it comes into contact with mercury has been developed to test levels of the metal in edible fish, such as tuna and swordfish, according to researchers in Spain.

Read More thumbnail image: Mercury lights up swordfish UV fluorophore

Living catalysis: Gold complex imaged with NIR in mice

Date: Mar 1, 2017

Author: David Bradley

The propargyl ester imaging probe Cy7.5-OProp was used as a near-infrared imaging probe for whole-body imaging to reveal how catalysis with a gold complex can be carried out in live mice, according to research published in the journal Angewandte Chemie.

Read More thumbnail image: Living catalysis Gold complex imaged with NIR in mice

Fab separations for Fab antibodies predicted by QSAR?

Date: Mar 1, 2017

Author: Ryan De Vooght-Johnson

Since an increasing array of separation methods are now used for proteins, interest is growing in using computational methods, such as quantitative structure–activity relationship (QSAR) calculations, to predict the likely response of proteins of interest to different systems, so that separations can be predicted. Researchers have used QSAR to predict the response of various antibody Fragment antigen-binding (Fab) fragments in different separation systems, with varying degrees of success.

Read More thumbnail image: Fab separations for Fab antibodies predicted by QSAR

Influenza attack: Raman to reveal hijack

Date: Mar 1, 2017

Author: David Bradley

Laura Fabris of Rutgers University, New York state, USA, and her colleagues are using surface enhanced Raman scattering (SERS) spectroscopy to investigate the role that might be played by TIPs - therapeutic interfering particles in defending us against influenza, flu.

Read More thumbnail image: Influenza attack Raman to reveal hijack

Reversing resistance: Rose myrtle extracts analysed by NMR

Date: Mar 1, 2017

Author: David Bradley

Novel natural products found in rose myrtle could hold promise of a new way to make breast cancer cells that have become resistant to the conventional anticancer drug doxorubicin susceptible once more. Nuclear magnetic resonance (NMR) spectroscopy, electronic circular dichroism (ECD) and X-ray crystallography were used to determine the structures and absolute configurations of the compounds.

Read More thumbnail image: Reversing resistance Rose myrtle extracts analysed by NMR

Cellular fusion: Protein X-ray insights

Date: Mar 1, 2017

Author: David Bradley

X-ray crystallography reveals that two closely related proteins, the HAP2 protein from the single-celled alga Chlamydomonas reinhardtii and the fusion protein from dengue virus are essential for fusion with a cell membrane and thus both sexual reproduction and viral invasion of a host cell. The proteins probably emerged very early in the history of life on Earth.

Read More thumbnail image: Cellular fusion Protein X-ray insights

New light on MRI: Contrast boost

Date: Mar 1, 2017

Author: David Bradley

A new technology platform can effectively tune the magnetic resonance imaging (MRI) signals in a scan switch on a contrast-boosting lamp on diseased tissue. Details are published in the journal Nature Materials suggesting that the approach might overcome some of the limitations of MRI contrast agents.

Read More thumbnail image: New light on MRI Contrast boost
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