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Journal Highlight: Applicability of micro-FTIR in detecting shale heterogeneity

Date: Jan 1, 2017

Author: spectroscopyNOW

Samples of shale from the Illinois Basin have been analysed by micro-FTIR spectroscopy and scanning electron microscopic X-ray spectroscopy to explore the distribution, connectivity and chemical composition of organic matter, clay minerals, carbonate minerals and quartz.

Read More thumbnail image: Journal Highlight Applicability of micro-FTIR in detecting shale heterogeneity

Journal Highlight: Laser ablation ICP-MS: Application in biomedical research

Date: Jan 1, 2017

Author: spectroscopyNOW

Recent biomedical applications in LA-ICP-MS imaging alone and in combination with molecular MSI techniques have been reviewed with applications in neurodegenerative diseases, distribution of contrast agents and metallodrugs, and metalloproteomics.

Read More thumbnail image: Journal Highlight Laser ablation ICP-MS Application in biomedical research

Journal Highlight: Early diagnosis of influenza virus A using surface-enhanced Raman scattering-based lateral flow assay

Date: Jan 1, 2017

Author: spectroscopyNOW

A SERS-based lateral flow assay (LFA) kit with SERS-active nanotags for the rapid diagnosis of influenza virus A has a limit of detection one order of magnitude better than a colorimetric LFA kit.

Read More thumbnail image: Journal Highlight Early diagnosis of influenza virus A using surface-enhanced Raman scattering-based lateral flow assay

Iranian chemists identify Russian chemical warfare agents

Date: Jan 1, 2017

Author: Ryan De Vooght-Johnson

All chemical weapons were banned by the Chemical Weapons Convention, but concerns about the possible use of these substances still persist. Writing in Rapid Communications in Mass Spectrometry, Iranian researchers disclose GC/MS and LC-MS/MS methods for detecting a number of the obscure ‘Novichok’ chemical warfare agents.

Read More thumbnail image: Iranian chemists identify Russian chemical warfare agents

Journal Highlight: Real-time MRI of swallowing: intraoral pressure reduction supports larynx elevation

Date: Dec 19, 2016

Author: spectroscopyNOW

The time course of intraoral pressure during swallowing has been evaluated using simultaneous real-time MRI and dynamic pressure recordings, showing that intraoral pressure reduction during swallowing supports laryngeal elevation by palatal fixation of the tongue.

Read More thumbnail image: Journal Highlight Real-time MRI of swallowing intraoral pressure reduction supports larynx elevation

Journal Highlight: Acute phase proteins as promising biomarkers: Perspectives and limitations for human and veterinary medicine

Date: Dec 19, 2016

Author: spectroscopyNOW

Current reviews on acute phase proteins and their use as biomarkers are discussed with examples of their general, extended and differential extrahepatic expression, leading to the conclusion that their diagnostic value should be reassessed.

Read More thumbnail image: Journal Highlight Acute phase proteins as promising biomarkers Perspectives and limitations for human and veterinary medicine

Large proteins: FTICR to the rescue

Date: Dec 16, 2016

Author: Steve Down

A powerful FTICR mass spectrometer installed recently in the National High Magnetic Field Laboratory in the USA has successfully observed thousands of protein isoforms in a top-down analysis, many of them with molecular masses above 30 kDa.

Read More thumbnail image: Large proteins FTICR to the rescue

Foetal tobacco smoke exposure: Touch spray meconium analysis

Date: Dec 15, 2016

Author: Steve Down

Nicotine and its metabolite cotinine have been measured in meconium from newborn children using the recently developed touch spray mass spectrometry technique which will reduce the time and cost of testing for in utero tobacco smoke exposure.

Read More thumbnail image: Foetal tobacco smoke exposure Touch spray meconium analysis

Bacterial insomnia: NMR finds dormancy inhibitors

Date: Dec 15, 2016

Author: David Bradley

Nuclear magnetic resonance (NMR) spectroscopy and other techniques have allowed an international team to reveal compounds that inhibit the bacterial ability to become dormant. Their work shows for the first time an oxygen-sensitive toxin-antitoxin system that might lead the way to new drugs to defeat bacterial resistance.

Read More thumbnail image: Bacterial insomnia NMR finds dormancy inhibitors

Asthma attack: Anti-inflammatory X-rayed

Date: Dec 15, 2016

Author: David Bradley

A new X-ray crystallographic study of the anti-inflammatory drug oxaprozin may lead to a new combined asthma therapy, according to research published by Singapore's Agency for Science, Technology and Research (A*STAR) in the journal RSC Advances.

Read More thumbnail image: Asthma attack Anti-inflammatory X-rayed
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