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Journal Highlight: Qualitative and quantitative characterization of protein biotherapeutics with liquid chromatography mass spectrometry

Date: Nov 6, 2017

Author: spectroscopyNOW

The technical challenges and strategies of LC/MS-based quantification and characterization of biotherapeutics have been reviewed, with emphasis on the analysis of antibody-based biotherapeutics such as monoclonal antibodies and antibody-drug conjugates.

Read More thumbnail image: Journal Highlight Qualitative and quantitative characterization of protein biotherapeutics with liquid chromatography mass spectrometry

Journal Highlight: In vivo X-ray imaging of transport of renal clearable gold nanoparticles in the kidneys

Date: Nov 6, 2017

Author: spectroscopyNOW

Noninvasive X-ray imaging of renal clearable gold nanoparticles in normal and nephropathic kidneys has advanced understanding of the nano-bio interactions while offering a new pathway to noninvasively image kidney dysfunction and local injuries at the anatomical level.

Read More thumbnail image: Journal Highlight Invivo X-ray imaging of transport of renal clearable gold nanoparticles in the kidneys

Journal Highlight: Ratiometric fluorescence detection of anthrax biomarker with EuIII-EDTA functionalized mixed poly(diacetylene) liposomes

Date: Nov 3, 2017

Author: spectroscopyNOW

Poly(diacetylene acid)-derived liposomes functionalized with Eu(III)-EDTA complexes have been developed as a ratiometric fluorescence detection system for the anthrax biomarker dipicolinate.

Read More thumbnail image: Journal Highlight Ratiometric fluorescence detection of anthrax biomarker with EuIII-EDTA functionalized mixed polydiacetylene liposomes

Compromised coffee: Soybean and corn adulterants by CE-MS

Date: Nov 1, 2017

Author: Steve Down

The adulteration of roasted coffee beans with coffee husks, corn or soybean has been detected using capillary electrophoresis-mass spectrometry to measure the monosaccharides originating from the constituent polysaccharides present in the beans.

Read More thumbnail image: Compromised coffee Soybean and corn adulterants by CE-MS

E-Cigarettes: As dangerous as cigarettes?

Date: Nov 1, 2017

Author: Steve Down

The safety of e-cigarettes has been thrown into doubt following new research which revealed that it induces high levels of proteins in the lungs that are linked with cystic fibrosis, COPD and bronchitis.

Read More thumbnail image: E-Cigarettes As dangerous as cigarettes

Clever chemometrics catches funny honey cheats

Date: Nov 1, 2017

Author: Ryan De Vooght-Johnson

Honey commands a variety of prices, depending in part on the source of the nectar from which it is derived, which may lead to fraudulent false labelling. Scientists from the Chinese Academy of Inspection and Quarantine in Beijing and Agilent Technologies (China) have devised a new method for detecting the source of honey samples, using GC-MS combined with chemometric methods.

Read More thumbnail image: Clever chemometrics catches funny honey cheats

X-rayed perovskites: Probably

Date: Nov 1, 2017

Author: David Bradley

Researchers in Japan have used Bayesian statistical analysis to help them work out the structure of a perovskite surface from its X-ray data.

Read More thumbnail image: X-rayed perovskites Probably

Targeted motor and sensory reinnervation: fMRI maps connection

Date: Nov 1, 2017

Author: David Bradley

Functional MRI has been used to demonstrate how the brain reqires its motor and sensory pathways when an amputee is given a robotic limb. Targeted motor and sensory reinnervation (TMSR) is a neuroprosthetic approach to connect residual limb nerves and reroute them to intact muscles and skin regions to give control the person control.

Read More thumbnail image: Targeted motor and sensory reinnervation fMRI maps connection

Heart stopping science: Raman sensor

Date: Nov 1, 2017

Author: David Bradley

A new device that uses resonance Raman spectroscopy can determine whether the body's tissues are adequately oxygenated and if placed on the heart, predict cardiac arrest in critically ill patients.

Read More thumbnail image: Heart stopping science Raman sensor

Incommunicado and in pain: IR to the rescue

Date: Nov 1, 2017

Author: David Bradley

Functional near-infrared spectroscopy (fNIRS) could offer hope to non-verbal patients who are suffering from pain allowing their carers and clinicians to observe episodes of pain even when the patient cannot communicate the problem.

Read More thumbnail image: Incommunicado and in pain IR to the rescue
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