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Answering Life's Questions with Spectroscopy

Date: Jun 28, 2017

Author: Jon Evans

Spectroscopy has been a common analytical technique in laboratories for many years. Recently, however, it has begun to emerge from the laboratory, both figuratively and literally, as more and more researchers discover that it is ideally placed to answer the questions they want to ask.

Read More thumbnail image: Answering Lifes Questions with Spectroscopy

Journal Highlight: Biomarker discovery by proteomics-based approaches for early detection and personalized medicine in colorectal cancer

Date: Jun 19, 2017

Author: spectroscopyNOW

An overview is presented of studies on colorectal cancer published in the last 5 years that led to the identification of protein biomarkers suitable for clinical application using proteomic approaches.

Read More thumbnail image: Journal Highlight Biomarker discovery by proteomics-based approaches for early detection and personalized medicine in colorectal cancer

Journal Highlight: Magnetic resonance imaging of the knee: An overview and update of conventional and state of the art imaging

Date: Jun 19, 2017

Author: spectroscopyNOW

The technical aspects of high-resolution MRI of the knee are discussed and the diagnostic criteria for detecting meniscal and cruciate tears with MRI is reviewed, including an update on knee MRI pertaining to advanced imaging.

Read More thumbnail image: Journal Highlight Magnetic resonance imaging of the knee An overview and update of conventional and state of the art imaging

Alzheimer's biomarkers: Novel metabolites and protein candidates

Date: Jun 15, 2017

Author: Steve Down

Scientists in China have identified a range of potential biomarkers of Alzheimer's disease from a metabolomics and proteomics study of the rat model, providing insight into diagnosis of the condition and candidates for therapeutic targets.

Read More thumbnail image: Alzheimers biomarkers Novel metabolites and protein candidates

Mosquito ID Parade: MALDI protein database

Date: Jun 15, 2017

Author: Steve Down

Mosquito species can be differentiated using their proteins which are identified by MALDI TOF mass spectrometry, providing a rapid and reliable way to identify disease vectors and form the basis of an international database.

Read More thumbnail image: Mosquito ID Parade MALDI protein database

Journal Highlight: Distinguishing individual DNA bases in a network by non-resonant tip-enhanced Raman scattering

Date: Jun 15, 2017

Author: spectroscopyNOW

Scanning tunneling microscope-controlled non-resonant TERS has been used to distinguish unambiguously between two individual complementary DNA bases (adenine and thymine) with a spatial resolution down to 0.9 nm.

Read More thumbnail image: Journal Highlight Distinguishing individual DNA bases in a network by non-resonant tip-enhanced Raman scattering

From heartbreak to happiness with in-house MS database

Date: Jun 15, 2017

Author: Ryan De Vooght-Johnson

Gelsemium elegans is a toxic plant of interest for its possible medical uses. Scientists from Hunan Agricultural University in China used a combination of LC-MS/MS and an in-house database of the accurate masses of previously detected Gelsemium compounds to tentatively identify a wide range of the many components in a crude extract from the plant.

Read More thumbnail image: From heartbreak to happiness with in-house MS database

Precisely helium: Single molecule calibration

Date: Jun 15, 2017

Author: David Bradley

Researchers from Aarhus University in Denmark and the Institute of Science and Technology in Austria have developed a new technique for aligning molecules using lasers and ultracold droplets of helium so they can precisely measure alignment.

Read More thumbnail image: Precisely helium Single molecule calibration

Lassa lashed: X-ray vaccine clue

Date: Jun 15, 2017

Author: David Bradley

Lassa fever can be lethal, it is a severe hemorrhagic disease caused by a single-stranded RNA virus in the arenavirus family. There is currently no vaccine. But that might soon change thanks to X-ray crystallographic work ten years in the making.

Read More thumbnail image: Lassa lashed X-ray vaccine clue

Stony coral: NMR and climate resistance

Date: Jun 15, 2017

Author: David Bradley

2D nuclear magnetic resonance (NMR) spectroscopy and ultra-high-resolution 3D imaging have been used to investigate a well-known and previously well-studied stony coral of the Indo-Pacific to reveal that it precipitates minerals through a biologically driven process. The findings suggest that this particular species may be more resistant to climate change than first thought.

Read More thumbnail image: Stony coral NMR and climate resistance
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