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Toxicity testing: The algorithms have it

Date: Aug 11, 2018

Author: David Bradley

A US study shows that database analysis more reliable than animal testing for toxic chemicals and could lead to computer algorithms replacing standard toxicology tests.

Read More thumbnail image: Toxicity testing The algorithms have it

Journal Highlight: X‐ray computed tomography and its potential in ecological research: A review of studies and optimization of specimen preparation

Date: Aug 6, 2018

Author: spectroscopyNOW

An overview is presented of recent developments of X‐ray computed tomography as an affordable, simple method of high spatial resolution to study 3D anatomy both in vivo and ex vivo.

Read More thumbnail image: Journal Highlight Xray computed tomography and its potential in ecological research A review of studies and optimization of specimen preparation

Journal Highlight: Interrogation of spatial metabolome of Ginkgo biloba with high‐resolution MALDI and LDI mass spectrometry imaging

Date: Aug 6, 2018

Author: spectroscopyNOW

Mass spectrometry imaging has been used to interrogate the spatio‐chemical localization of metabolites across the ginkgo leaf using MALDI and LDI FTICR MS.

Read More thumbnail image: Journal Highlight Interrogation of spatial metabolome of Ginkgo biloba with highresolution MALDI and LDI mass spectrometry imaging

Journal Highlight: Reversible switching between phosphorescence and fluorescence in a unimolecular system controlled by external stimuli

Date: Aug 6, 2018

Author: spectroscopyNOW

A dual‐emissive hexathiobenzene‐based molecule has been reported with significant aggregation‐induced phosphorescence characteristics and reversible switching among blue, green, and yellow phosphorescence that will help to develop smart materials and intelligent optoelectronic devices.

Read More thumbnail image: Journal Highlight Reversible switching between phosphorescence and fluorescence in a unimolecular system controlled by external stimuli

Illicit fentanyls: Paper spray mass spectrometry for testing in the field

Date: Aug 1, 2018

Author: Steve Down

Fentanyl-type drugs of abuse have been screened, identified and measured in urine by paper spray mass spectrometry in a procedure which could be developed into point-of-use testing for forensic and emergency personnel.

Read More thumbnail image: Illicit fentanyls Paper spray mass spectrometry for testing in the field

Fatigue in multiple sclerosis: Protein biomarkers

Date: Aug 1, 2018

Author: Steve Down

Several biomarkers of fatigue in patients with multiple sclerosis have been identified in a proteomics study, pointing to a disturbance of central nervous system plasticity as a key factor.

Read More thumbnail image: Fatigue in multiple sclerosis Protein biomarkers

Jovian ribbon: Infrared band

Date: Aug 1, 2018

Author: David Bradley

Scientists in the UK have used the NSFCam instrument at the NASA Infrared Telescope Facility to overturn an earlier theory about dark ribbon of weak hydrogen ion emissions that encircles Jupiter. The research could reshape our thinking about the giant planet's magnetic equator.

Read More thumbnail image: Jovian ribbon Infrared band

Multiple Sclerosis: MRI shows brain iron link

Date: Aug 1, 2018

Author: David Bradley

Researchers at the University at Buffalo in Buffalo, New York, USA have used a magnetic resonance imaging (MRI) technique, quantitative susceptibility mapping, to measure the concentration of iron in the brains of multiple sclerosis patients. They examined 600 patients, 452 with early-stage disease, and 148 with more advanced disease, and found that when compared with the control group, the MS patients had higher levels of iron in the basal ganglia and lower levels of iron in the thalamus.

Read More thumbnail image: Multiple Sclerosis MRI shows brain iron link

Tethered DNA nanorods: UV lines them up

Date: Aug 1, 2018

Author: David Bradley

A combination of ultraviolet-visible (UV-Vis) spectroscopy and small-angle X-ray scattering have been used to investigate how DNA "linker" strands can coax nano-sized rods to line up in a manner unlike any other spontaneous arrangement of rod-shaped objects.

Read More thumbnail image: Tethered DNA nanorods UV lines them up

Fungal killer: NMR reveals wall architecture

Date: Aug 1, 2018

Author: David Bradley

There are very few effective antifungal agents in the pharmaceutical arsenal and unfortunately, many types of fungal infection can kill. New research based on solid-state nuclear magnetic resonance (NMR) spectroscopy has looked at fungal cell wall and revealed details of its architecture that might be a new target for drugs to combat such infections.

Read More thumbnail image: Fungal killer NMR reveals wall architecture
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