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rssJournal Highlight: Comparison of direct mass spectrometry methods for the on-line analysis of volatile compounds in foods
Date: Jun 10, 2013
Author: spectroscopyNOW
This study highlighted the equivalent performances of APCI-MS and PTR-MS for in vitro and in vivo flavour release investigations and provided useful data on the problematic use of sample bags for headspace analyses.
Read MoreJournal Highlight: Spectroscopic studies on nicotine and nornicotine in the UV region
Date: Jun 10, 2013
Author: spectroscopyNOW
The UV absorption and electronic circular dichroism (ECD) spectra of (R)- and (S)-nicotine and (S)-nornicotine in aqueous solution were measured to a significantly lower wavelength range than previously reported, allowing the identification of four previously unobserved electronic transitions.
Read MoreJournal Highlight: Assessment of higher order structure comparability in therapeutic proteins using nuclear magnetic resonance spectroscopy
Date: Jun 3, 2013
Author: spectroscopyNOW
NMR spectroscopy using a fingerprinting approach has been used to rapidly assess higher order structure comparability in three nonglycosylated proteins spanning a molecular weight range of 6.5–67 kDa.
Read MoreJournal Highlight: Ultra-trace silver determination in biological and water samples by EAAS after electrodeposition on a graphite probe
Date: Jun 3, 2013
Author: spectroscopyNOW
A rapid and simple procedure was developed for the selective and sensitive determination of ultra-trace silver in biological and environmental samples using the electrodeposition on a graphite probe modified with palladium followed by electrothermal atomic absorption spectrometry.
Read MoreJournal Highlight: In vivo probing of the temperature responses of intracellular biomolecules in yeast cells by label-free Raman microspectroscopy
Date: Jun 3, 2013
Author: spectroscopyNOW
The in vivo probing, achieved with label-free Raman microspectroscopy, of the temperature responses of major intracellular components such as lipids and proteins in living fission yeast cells is presented.
Read MoreJournal Highlight: Mid-infrared (IR) – A hot topic: The potential for using mid-IR light for non-invasive early detection of skin cancer in vivo
Date: Jun 3, 2013
Author: spectroscopyNOW
The remarkable progress made towards mid-IR spectral in vitro mapping of tissue and cancer detection is reviewed and the status quo of chalcogenide glass mid-IR fibre optics and photonics for remote mid-IR sensing in general, and in vivo cancer detection in particular, is assessed.
Read MoreFilter paper prop: Support for biological samples in well plates for forensic drug analysis
Date: Jun 1, 2013
Author: Steve Down
Filter paper has been used as a support in 96-well plates for ten types of biological fluids and tissues in the post-mortem LC/MS analysis of the alkaloid colchicine, in which the calibration curve for dried blood spots can be applied to most of the other sample types.
Read MorePancreatic poser: Interspecies effects of nicotine on proteome
Date: Jun 1, 2013
Author: Steve Down
Nicotine affects pancreatic stellate cells from different species in similar ways, suggesting common interaction pathways that will help to understand the link between smoking and pancreatic disease, say researchers in the US.
Read MoreColours to dye for: Spray on pigments
Date: Jun 1, 2013
Author: David Bradley
Japanese scientists have developed a new type of colouring agent that is not only environmentally friendly but does not fade like conventional textile dyes and pigments. The colourants consist of submicrometre-sized silicon dioxide particles and carbon black and can be sprayed on to the desired surface to generate bright colours that are permanent and highly fade resistant.
Read MoreDiffract and destroy: Fluctuation X-ray scattering
Date: Jun 1, 2013
Author: David Bradley
Fluctuation X-ray scattering could help fill the gaps in our knowledge of protein structure thanks to the short bursts of radiation allowing data to be obtained from non-crystallisable proteins in their native, fluid state albeit with the sacrifice of the protein itself.
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