EarlyView Articles

Skip to Navigation

The very latest articles from the scientific literature
on Wiley Online Library...


You can keep up-to date on these EarlyView articles, which focus on spectroscopy
and separation science:

Earlyview RSS Feed

rss

Filter by Journal

Browse By Journal

Biomineralization in saxicolous lichens: Raman spectroscopic study supported with XRF and SEM‐EDX analyses

Published: Aug 24, 2016

Author(s): I. Ibarrondo, I. Martínez‐Arkarazo, J. M. Madariaga

Journal: Journal of Raman Spectroscopy

This study demonstrates the applicability of Raman spectroscopy, assisted with X‐ray fluorescence and scanning electron microscopy–energy dispersive X‐ray spectroscopy analyses, in the characterization of biominerals accumulated on several stone materials colonized by saxicolous lichens under different environmental conditions. The distribution of the diverse biominerals through the lichen–stone interface is described. Among them,...

Read More thumbnail image: Biomineralization in saxicolous lichens Raman spectroscopic study supported with XRF and SEMEDX analyses

Development of electrostatic spherical aberration corrector using annular and circular electrodes

Published: Aug 24, 2016

Author(s): Tadahiro Kawasaki, Takafumi Ishida, Yasuyuki Takai, Yuki Ogawa, Masahiro Tomita, Takaomi Matsutani, Tetsuji Kodama, Takashi Ikuta

Journal: Surface and Interface Analysis

The spherical aberration corrector for high‐resolution electron microscopes has been newly designed and constructed. This aberration correction device is formed by an electrostatic lens consisted of only two electrodes having annular and circular holes and a constant‐voltage supply. We call it ‘annular and circular electrodes (ACE) corrector’. The ACE corrector has big advantages in easy alignment and very low‐cost over the conventional...

Read More thumbnail image: Development of electrostatic spherical aberration corrector using annular and circular electrodes

A researcher's guide to mass spectrometry‐based proteomics

Published: Aug 24, 2016

Author(s): John P. Savaryn, Timothy K. Toby, Neil L. Kelleher

Journal: PROTEOMICS

Mass spectrometry (MS) is widely recognized as a powerful analytical tool for molecular research. MS is used by researchers around the globe to identify, quantify, and characterize biomolecules like proteins from any number of biological conditions or sample types. As instrumentation has advanced, and with the coupling of liquid chromatography (LC) for high‐throughput LC‐MS/MS, a proteomics experiment measuring hundreds to thousands of...

Read More thumbnail image: A researchers guide to mass spectrometrybased proteomics

De novo peptide sequencing using CID and HCD spectra pairs

Published: Aug 24, 2016

Author(s): Yan Yan, Anthony J. Kusalik, Fang‐Xiang Wu

Journal: PROTEOMICS

In tandem mass spectrometry (MS/MS), there are several different fragmentation techniques possible, including, collision‐induced dissociation (CID) higher energy collisional dissociation (HCD), electron‐capture dissociation (ECD), and electron transfer dissociation (ETD). When using pairs of spectra for de novo peptide sequencing, the most popular methods are designed for CID (or HCD) and ECD (or ETD) spectra because of the complementarity ...

Read More thumbnail image: De novo peptide sequencing using CID and HCD spectra pairs

Sol–gel coating of poly(ethylene glycol)‐grafted multiwalled carbon nanotubes for stir bar sorptive extraction and its application to the analysis of polycyclic aromatic hydrocarbons in water

Published: Aug 24, 2016

Author(s): Nadiya Ekbatani Amlashi, Mohammad Reza Hadjmohammadi

Journal: Journal of Separation Science

Poly(ethylene glycol) grafted onto carboxyl‐terminated multi‐walled carbon nanotubes were prepared by the sol–gel technique as a stationary phase for stir bars. The analytical methodology included stir bar sorptive extraction with micellar desorption followed by liquid chromatography. Polycyclic aromatic hydrocarbons were used as the model compounds to evaluate the extraction performance. The extraction efficiency, for the determination...

Read More thumbnail image: Solgel coating of polyethylene glycolgrafted multiwalled carbon nanotubes for stir bar sorptive extraction and its application to the analysis of polycyclic aromatic hydrocarbons in water

Study on the interactions of sulfonylurea antidiabetic drugs with normal and glycated human serum albumin by capillary electrophoresis with frontal analysis

Published: Aug 24, 2016

Author(s): Lenka Michalcová, Zdeněk Glatz

Journal: Journal of Separation Science

Diabetes is one of the most widespread diseases characterized by a deficiency in the production of insulin or its ineffectiveness. As a result, the increased concentrations of glucose in the blood lead not only to damage to many of the body's systems but also cause the nonenzymatic glycation of plasma proteins affecting their drug binding. Since the binding ability influences its pharmacokinetics and pharmacodynamics, this is a very...

Read More thumbnail image: Study on the interactions of sulfonylurea antidiabetic drugs with normal and glycated human serum albumin by capillary electrophoresis with frontal analysis

Characterization of a novel MR‐detectable nanoantioxidant that mitigates the recall immune response

Published: Aug 24, 2016

Author(s): Taeko Inoue, Deric M. Griffin, Redwan Huq, Errol L. G. Samuel, Simone H. Ruano, Gary Stinnett, Tabassum J. Majid, Christine Beeton, James M. Tour, Robia G. Pautler

Journal: NMR in Biomedicine

In many human diseases, the presence of inflammation is associated with an increase in the level of reactive oxygen species (ROS). The resulting state of oxidative stress is highly detrimental and can initiate a cascade of events that ultimately lead to cell death. Thus, many therapeutic attempts have been focused on either modulating the immune system to lower inflammation or reducing the damaging caused by ROS. Berlin et al. reported...

Read More thumbnail image: Characterization of a novel MRdetectable nanoantioxidant that mitigates the recall immune response

Diffusion‐weighted MRI of breast lesions: a prospective clinical investigation of the quantitative imaging biomarker characteristics of reproducibility, repeatability, and diagnostic accuracy

Published: Aug 24, 2016

Author(s): Claudio Spick, Hubert Bickel, Katja Pinker, Maria Bernathova, Panagiotis Kapetas, Ramona Woitek, Paola Clauser, Stephan H. Polanec, Margaretha Rudas, Rupert Bartsch, Thomas H. Helbich, Pascal A. Baltzer

Journal: NMR in Biomedicine

Diffusion‐weighted MRI (DWI) provides insights into tissue microstructure by visualization and quantification of water diffusivity. Quantitative evaluation of the apparent diffusion coefficient (ADC) obtained from DWI has been proven helpful for differentiating between malignant and benign breast lesions, for cancer subtyping in breast cancer patients, and for prediction of response to neoadjuvant chemotherapy. However, to...

Read More thumbnail image: Diffusionweighted MRI of breast lesions a prospective clinical investigation of the quantitative imaging biomarker characteristics of reproducibility repeatability and diagnostic accuracy

Risk of false positive results to SARM S‐4 in case of therapeutic use of antineoplastic/antiandrogen drug containing flutamide: a case study

Published: Aug 23, 2016

Author(s): L. Perrenoud, C. Schweizer Grundisch, N. Baume, M. Saugy, R. Nicoli

Journal: Drug Testing and Analysis

Read More thumbnail image: Risk of false positive results to SARM S4 in case of therapeutic use of antineoplasticantiandrogen drug containing flutamide a case study

Orthogonality, uncorrelatedness, and linear independence of vectors

Published: Aug 23, 2016

Author(s): Richard G. Brereton

Journal: Journal of Chemometrics

Read More thumbnail image: Orthogonality uncorrelatedness and linear independence of vectors

Retaining in‐gel zymographic activity of cysteine proteases via a cysteine‐supplemented running buffer

Published: Aug 23, 2016

Author(s): Sreekanth Vootukuri Reddy, Mike P. Philpott, Giuseppe Trigiante

Journal: ELECTROPHORESIS

Zymography is a powerful technique to separate and identify different enzymatic activities on a standard acrylamide gel. For oxidation prone enzymes such as cysteine proteases however, the oxidizing species generated by electrolysis of the gel running buffer may result in partial or complete inactivation, thus compromising the final readout. This can be only partially remedied by subsequent treatment of the gel with reducing agents. We...

Read More thumbnail image: Retaining ingel zymographic activity of cysteine proteases via a cysteinesupplemented running buffer

Sensitive detection of proteins in polyacrylamide gel via isatoic anhydride derivatization: Introduction of a low‐cost fluorescent prelabeling procedure

Published: Aug 23, 2016

Author(s): Kazem Asadollahi, Saharnaz Rafiee, Gholamhossein Riazi

Journal: ELECTROPHORESIS

Here, we introduce isatoic anhydride as a sensitive and commodious fluorescent prelabel for detection of proteins in one‐dimensional polyacrylamide gels. High reactivity of isatoic anhydride with nucleophiles in mild alkaline environments makes it an appropriate tag for labeling of biomolecules. In this study, we show that preelectrophoresis labeling of proteins with isatoic anhydride for few minutes at room temperature allows detection...

Read More thumbnail image: Sensitive detection of proteins in polyacrylamide gel via isatoic anhydride derivatization Introduction of a lowcost fluorescent prelabeling procedure

Online preconcentration by electrokinetic supercharging for separation of endocrine disrupting chemical and phenolic pollutants in water samples

Published: Aug 23, 2016

Author(s): Nurul ’I. Abdul Karim, Wan A. Wan Ibrahim, Mohd M. Sanagi, Aemi S. Abdul Keyon

Journal: ELECTROPHORESIS

Online preconcentration using electrokinetic supercharging (EKS) was proposed to enhance the sensitivity of separation for endocrine disrupting chemical (methylparaben (MP)) and phenolic pollutants (2‐nitrophenol (NP) and 4‐chlorophenol (CP)) in water sample. Important EKS and separation conditions such as the concentration of BGE; the choice of terminating electrolyte (TE); and the injection time of leading electrolyte (LE), sample, and...

Read More thumbnail image: Online preconcentration by electrokinetic supercharging for separation of endocrine disrupting chemical and phenolic pollutants in water samples

In vitro metabolism of specific CYP2D and CYP3A opioid substrates using rat liver S9 fractions and mass spectrometry reveal a severe metabolic impairment with increasing age

Published: Aug 23, 2016

Author(s): Sabrin Fuad Salmin, Marie‐Chantal Giroux, Pascal Vachon, Francis Beaudry

Journal: Biomedical Chromatography

Abstract Codeine and oxycodone are opioids used to alleviate pain. The outcome of the treatment is ultimately related to their metabolism by Cytochromes P450 (CYPs). Depending on the drugs used, alterations in the metabolism of drugs by CYPs can lead to severe consequences including alterations in their efficacy, safety and toxicity. The objectives of this study were to develop a novel HPLC–MS/MS method capable of quantifying...

Read More thumbnail image: In vitro metabolism of specific CYP2D and CYP3A opioid substrates using rat liver S9 fractions and mass spectrometry reveal a severe metabolic impairment with increasing age

Rapid magnetic solid‐phase extraction of Congo Red and Basic Red 2 from aqueous solution by ZIF‐8@CoFe 2 O 4 hybrid composites

Published: Aug 22, 2016

Author(s): Yan Xu, Jingjie Jin, Xianliang Li, Yide Han, Hao Meng, Junbiao Wu, Xia Zhang

Journal: Journal of Separation Science

Core–shell metal–organic framework materials have attracted considerable attention mainly due to their enhanced or new physicochemical properties compared with their single‐component counterparts. In this work, a core–shell heterostructure of CoFe2O4‐Zeolitic Imidazolate Framework‐8 (ZIF‐8@CoFe2O4) is successfully fabricated and used as an solid‐phase extraction adsorbent to efficiently extract Congo Red and Basic Red 2 dyes from contaminated aqueous...

Read More thumbnail image: Rapid magnetic solidphase extraction of Congo Red and Basic Red 2 from aqueous solution by ZIF8CoFe 2 O 4 hybrid composites

Multiple analytical methods for identification and quality evaluation of Fritillariae Thunbergii Bulbus based on biological single molecules by high‐performance liquid chromatography

Published: Aug 22, 2016

Author(s): Chao Zhang, Lei Sun, Rong Chen, Jing‐hua Su, Hua‐feng Zhang, Bing‐ren Gu, Yi‐wen Xing, Man Xue

Journal: Journal of Separation Science

Quantitative analysis for biological single molecules in Fritillariae Thunbergii Bulbus and identification method by chemometrics was established by using high‐performance liquid chromatography. Amino acids, nucleosides, and nucleobases were quantitatively analyzed, and 11 peaks were selected for species identification. A Common pattern was established for chemometrics, and then similarity analysis, principal component analysis, and...

Read More thumbnail image: Multiple analytical methods for identification and quality evaluation of Fritillariae Thunbergii Bulbus based on biological single molecules by highperformance liquid chromatography

Polypyrrole‐coated alginate/magnetite nanoparticles composite sorbent for the extraction of endocrine‐disrupting compounds

Published: Aug 22, 2016

Author(s): Opas Bunkoed, Piyaluk Nurerk, Rodtichoti Wannapob, Proespichaya Kanatharana

Journal: Journal of Separation Science

Magnetite nanoparticles incorporated into alginate beads and coated with a polypyrrole adsorbent were prepared (polypyrrole/Fe3O4/alginate bead) and used as an effective magnetic solid‐phase extraction sorbent for the extraction and enrichment of endocrine‐disrupting compounds (estriol, β‐estradiol and bisphenol A) in water samples. The determination of the extracted endocrine‐disrupting compounds was performed using high‐performance liquid...

Read More thumbnail image: Polypyrrolecoated alginatemagnetite nanoparticles composite sorbent for the extraction of endocrinedisrupting compounds

Development of deep eutectic solvents applied in extraction and separation

Published: Aug 22, 2016

Author(s): Xiaoxia Li, Kyung Ho Row

Journal: Journal of Separation Science

Deep eutectic solvents, as an alternative to ionic liquids, have greener credentials than ionic liquids, and have attracted considerable attention in related chemical research. Deep eutectic solvents have attracted increasing attention in chemistry for the extraction and separation of various target compounds from natural products. This review highlights the preparation of deep eutectic solvents, unique properties of deep eutectic...

Read More thumbnail image: Development of deep eutectic solvents applied in extraction and separation

Phenylboronic acid modified solid‐phase extraction column: Preparation, characterization, and application to the analysis of amino acids in sepia capsule by removing the maltose

Published: Aug 22, 2016

Author(s): Mengzhe Guo, Dengyang Yin, Jie Han, Liyan Zhang, Xiao Li, Dandan He, Yan Du, Daoquan Tang

Journal: Journal of Separation Science

Maltose, a common auxiliary material of pharmaceutical preparation, may disturb the analysis of total amino acids in sepia capsule by aldolization. Therefore, it is necessary to remove the maltose through a convenient method. In this work, a phenylboronic acid modified solid‐phase extraction column has been synthesized and used to remove the maltose. The materials were synthesized by one step “thiol‐ene” reaction and the parameters of the...

Read More thumbnail image: Phenylboronic acid modified solidphase extraction column Preparation characterization and application to the analysis of amino acids in sepia capsule by removing the maltose

Development of a stir bar sorptive extraction method for the determination of volatile compounds in orange juices

Published: Aug 22, 2016

Author(s): Carla Herrera, Remedios Castro, Carmelo García‐Barroso, Enrique Durán‐Guerrero

Journal: Journal of Separation Science

A stir bar sorptive extraction method for the determination of volatile compounds in orange juices was developed. The extraction variables were optimized using a reduced two‐level factorial screening design (25‐1), and the most suitable analytical conditions for the extraction of the studied compounds were: sample volume 10 mL, extraction time 60 min, stirring speed 1800 rpm, NaCl amount 30% (weight/volume), and twister length 10 mm. The optimized...

Read More thumbnail image: Development of a stir bar sorptive extraction method for the determination of volatile compounds in orange juices
Page:   1 2 3 4 5 6 Next

Social Links

Share This Links

Bookmark and Share

Microsites

Suppliers Selection
Societies Selection

Banner Ad

Click here to see
all job opportunities

Most Viewed

Copyright Information

Interested in separation science? Visit our sister site separationsNOW.com

Copyright © 2016 John Wiley & Sons, Inc. All Rights Reserved