EarlyView Articles

Skip to Navigation

The very latest articles from the scientific literature
on Wiley Online Library...


You can keep up-to date on these EarlyView articles, which focus on spectroscopy
and separation science:

Earlyview RSS Feed

rss

Filter by Journal

Browse By Journal

3D Multilayered paper‐ and thread/paper‐based microfluidic devices for bioassays

Published: Nov 15, 2018

Author(s): Natalia M. Neris, Ricardo D. Guevara, Ariana Gonzalez, Frank A. Gomez

Journal: ELECTROPHORESIS

Abstract In this paper we describe the fabrication of novel 3D microfluidic paper‐based analytical devices (3D‐μPADs) and a 3D microfluidic thread/paper‐based analytical device (3D‐μTPAD) to detect glucose and BSA through colorimetric assays. The 3D‐μPAD and 3D‐μTPAD consisted of three (wax, heat pressed wax‐printed paper, single‐sided tape) and four (hole‐punched single‐sided tape, blank chromatography circles, heat‐pressed...

Read More thumbnail image: 3D Multilayered paper and threadpaperbased microfluidic devices for bioassays

Three‐dimensional NMR microscopy of zebrafish specimens

Published: Nov 15, 2018

Author(s): Timothy L. Kline, Caroline R. Sussman, Maria V. Irazabal, Prasanna K. Mishra, Elisabeth A. Pearson, Vicente E. Torres, Slobodan I. Macura

Journal: NMR in Biomedicine

While zebrafish embryos in the first five days after fertilization are clear and amenable to optical analysis, older juveniles and adults are not, due to pigmentation development and tissue growth. Thus other imaging methods are needed to image adult specimens. NMR is a versatile tool for studies of biological systems and has been successfully used for in vivo zebrafish microscopy. In this work we use NMR microscopy (MRM) for assessment...

Read More thumbnail image: Threedimensional NMR microscopy of zebrafish specimens

XPS primary excitation spectra of Zn 2 p , Fe 2 p , and Ce 3 d from ZnO, α‐Fe 2 O 3 , and CeO 2

Published: Nov 15, 2018

Author(s): Nicolas Pauly, Francisco Yubero, Juan Pedro Espinós, Sven Tougaard

Journal: Surface and Interface Analysis

Metal oxides are important for current development in nanotechnology. X‐ray photoelectron spectroscopy(XPS) is a widely used technique to study the oxidation states of metals, and a basic understanding of the photoexcitation process is important to obtain the full information from XPS. We have studied core level excitations of Zn 2p, Fe 2p, and Ce 3d photoelectron emissions from ZnO, α‐Fe2O3, and CeO2. Using an effective energy‐differential XPS...

Read More thumbnail image: XPS primary excitation spectra of Zn 2 p  Fe 2 p  and Ce 3 d from ZnO Fe 2 O 3  and CeO 2

MRI evaluation of vulvar squamous‐cell carcinoma in fresh radical local excision specimens for cancer localization and prediction of surgical tumor‐free margins

Published: Nov 15, 2018

Author(s): Jan Heidkamp, Petra L.M. Zusterzeel, Adriana C.H. Engen‐van Grunsven, Christiaan G. Overduin, Andor Veltien, Arie Maat, Maroeska M. Rovers, Jurgen J. Fütterer

Journal: NMR in Biomedicine

In the surgical treatment of vulvar squamous‐cell carcinoma (VSCC), tumor‐free margins of 8 mm or more are considered adequate. However, limited perioperative information on the tumor‐free margins other than the surgeon's own estimation is available. The purpose of this study was therefore to investigate the feasibility of ex vivo MRI in localizing VSCC and to assess the surgical tumor‐free margins in fresh radical local excision...

Read More thumbnail image: MRI evaluation of vulvar squamouscell carcinoma in fresh radical local excision specimens for cancer localization and prediction of surgical tumorfree margins

Highly sensitive and rapid determination of tacrolimus in peripheral blood mononuclear cells by liquid chromatography–tandem mass spectrometry

Published: Nov 14, 2018

Author(s): Soma Bahmany, Lucia E.A. Wit, Dennis A. Hesselink, Teun Gelder, Nauras M. Shuker, Carla Baan, Bart C.H. Nagel, Birgit C.P. Koch, Brenda C.M. Winter

Journal: Biomedical Chromatography

Abstract After solid organ transplantation, tacrolimus is given to prevent rejection. Therapeutic drug monitoring is used to reach target concentrations of tacrolimus in whole blood. Because the site of action of tacrolimus is the lymphocyte, and tacrolimus binds ~80% to erythrocytes, the intracellular tacrolimus concentration in lymphocytes is possibly more relevant. For this purpose, we aimed to develop, improve and validate a...

Read More thumbnail image: Highly sensitive and rapid determination of tacrolimus in peripheral blood mononuclear cells by liquid chromatographytandem mass spectrometry

Simultaneous determination of broflanilide and its metabolites in five typical Chinese soils by a modified quick, easy, cheap, effective, rugged, and safe method with ultra high performance liquid chromatography and tandem mass spectrometry

Published: Nov 14, 2018

Author(s): Xiaokang An, Jun Xu, Fengshou Dong, Xingang Liu, Xiaohu Wu, Ran Wang, Yongquan Zheng

Journal: Journal of Separation Science

Abstract An efficient and sensitive analytical method for simultaneous determination of trace amounts of a new insecticide broflanilide and its metabolites (S(PFH‐OH)‐8007 and DM‐8007) residues in five typical Chinese soils (red soil, black soil, fluvo‐aquic soil, cinnamon soil and paddy soil) was developed. The samples were prepared by a modified quick, easy, cheap, effective, rugged, and safe method. The determination of...

Read More thumbnail image: Simultaneous determination of broflanilide and its metabolites in five typical Chinese soils by a modified quick easy cheap effective rugged and safe method with ultra high performance liquid chromatography and tandem mass spectrometry

Electromembrane extraction of verapamil and riluzole from urine and wastewater samples using a mixture of organic solvents as a supported liquid membrane: Study on electric current variations

Published: Nov 14, 2018

Author(s): Atyeh Rahimi, Saeed Nojavan

Journal: Journal of Separation Science

Abstract In this study, the application of a mixture of organic solvents as a supported liquid membrane for improving the efficiency of the electromembrane extraction procedure was investigated. The extraction process was followed by high‐performance liquid chromatography analysis of two model drugs (verapamil and riluzole). In this research, four organic solvents, including 1‐heptanol, 1‐octanol, 2‐nitrophenyl octyl ether, and...

Read More thumbnail image: Electromembrane extraction of verapamil and riluzole from urine and wastewater samples using a mixture of organic solvents as a supported liquid membrane Study on electric current variations

A novel in‐capillary assay for dynamically monitoring fast binding between antibody and peptides using CE

Published: Nov 14, 2018

Author(s): Jianhao Wang, Lin Qiu, Ying You, Luping Ma, Zhilan Zhu, Li Yang, Jianpeng Wang, Xiang Wang, Li Liu, Xiaoqian Liu, Yufeng Chang, Jie Li, Liqian Gao, Yong‐Qiang Li

Journal: Journal of Separation Science

Abstract Nowadays, despite numerous techniques available for the detection of antibody–peptide binding, sensitivity and detection limit inflow still remains a major challenge. Herein, we report a strategy for the detection of binding inflow of monoclonal anti‐FLAG M2 antibody and 5,6‐carboxyfluorescein‐labeled FLAG tag in capillary. Antibody and peptides were sequentially injected into the capillary where they mixed and bound...

Read More thumbnail image: A novel incapillary assay for dynamically monitoring fast binding between antibody and peptides using CE

Accurate and sensitive determination of sildenafil, tadalafil, vardenafil, and avanafil in illicit erectile dysfunction medications and human urine by LC with quadrupole‐TOF‐MS/MS and their behaviors in simulated gastric conditions

Published: Nov 14, 2018

Author(s): Elif Öztürk Er, Belma Özbek, Sezgin Bakırdere

Journal: Journal of Separation Science

Abstract The widespread use of phosphodiesterase‐5 inhibitors has attracted broad attention of counterfeiters to develop illicit erectile products with inaccurate amounts, unknown toxicity, and purity of active ingredients. Correspondingly, intake of these products endangers consumer health and needs to be screened for precautionary actions to reduce this risk. Therefore, in this study, a sensitive and rapid analytical method has...

Read More thumbnail image: Accurate and sensitive determination of sildenafil tadalafil vardenafil and avanafil in illicit erectile dysfunction medications and human urine by LC with quadrupoleTOFMSMS and their behaviors in simulated gastric conditions

Microwave‐assisted‐demulsification dispersive liquid–liquid microextraction for the determination of triazole fungicides in water by gas chromatography with mass spectrometry

Published: Nov 14, 2018

Author(s): Peng Wang, Yiping Zhao, Xiajun Wang, Guo‐Wei Yu, Jian Wang, Zu‐Guang Li, Maw‐Rong Lee

Journal: Journal of Separation Science

Abstract A novel microwave‐assisted‐demulsification dispersive liquid–liquid microextraction technique was established for determination of three triazole fungicides in environmental water samples by gas chromatography with mass spectrometry. Importantly, microwave irradiation has been applied in demulsification to achieve the phase separation and enrichment of triazole fungicides in water samples successfully with low‐density...

Read More thumbnail image: Microwaveassisteddemulsification dispersive liquidliquid microextraction for the determination of triazole fungicides in water by gas chromatography with mass spectrometry

Critical evaluation of microextraction pretreatment techniques—Part 2: Membrane‐supported and homogenous phase based techniques

Published: Nov 14, 2018

Author(s): Martina Havlikova, Radomir Cabala, Vera Pacakova, Zuzana Bosakova

Journal: Journal of Separation Science

Abstract This review follows up on Part 1, which focused on classification and evaluation of single drop and sorbent‐based microextraction techniques. Membrane‐ and homogenous phase‐based microextraction techniques are discussed and classified in Part 2. These techniques are more recent than those in Part 1 and considerable attention has been paid to their development. The new methodologies are more sensitive and, thanks to their...

Read More thumbnail image: Critical evaluation of microextraction pretreatment techniquesPart 2 Membranesupported and homogenous phase based techniques

Glucagon infusion alters the hyperpolarized 13 C‐urea renal hemodynamic signature

Published: Nov 14, 2018

Author(s): Haiyun Qi, Christian Østergaard Mariager, Per Mose Nielsen, Marie Schroeder, Jakob Lindhardt, Rikke Nørregaard, Janet D. Klein, Jeff M. Sands, Christoffer Laustsen

Journal: NMR in Biomedicine

Renal urea handling is central to the urine concentrating mechanism, and as such the ability to image urea transport in the kidney is an important potential imaging biomarker for renal functional assessment. Glucagon levels associated with changes in dietary protein intake have been shown to influence renal urea handling; however, the exact mechanism has still to be fully understood. Here we investigate renal function and osmolite...

Read More thumbnail image: Glucagon infusion alters the hyperpolarized 13 Curea renal hemodynamic signature

Sub‐minute determination of rifampicin and isoniazid in fixed dose combination tablets by capillary zone electrophoresis with ultraviolet absorption detection

Published: Nov 13, 2018

Author(s): Lucas Mattos Duarte, Tatiane Lima Amorim, Paula Rocha Chellini, Luiz Henrique Cantarino Adriano, Marcone Augusto Leal Oliveira

Journal: Journal of Separation Science

Abstract A validated sub minute capillary zone electrophoresis method with direct ultraviolet absorption detection for simultaneous determination of isoniazid and rifampicin in fixed‐dose combination tablets was developed. Background electrolyte was defined based on the analytes effective mobility curve and it was composed by 20 mmol/L of sodium carbonate/sodium bicarbonate at pH 10.2. A careful validation procedure considering...

Read More thumbnail image: Subminute determination of rifampicin and isoniazid in fixed dose combination tablets by capillary zone electrophoresis with ultraviolet absorption detection

Poly glycidyl methacrylate‐co‐ethylene dimethacrylate porous monolith as a versatile platform for the development of separations and solid‐phase extractions in sequential injection analyzers

Published: Nov 13, 2018

Author(s): Luiz F. Ribeiro, Renan Lopes Martins, Diego M. de Souza Costa, Jorge C. Masini

Journal: Journal of Separation Science

Abstract We demonstrated that the porous structure and the reactivity of the epoxy group in the poly glycidyl methacrylate‐co‐ethylene dimethacrylate monolith can be a platform for the development of separation and extraction methods based on sequential injection analysis. The epoxy group was functionalized to produce monoliths affording complexing and ion exchange properties. Derivatization with iminodiacetate and sodium sulfite...

Read More thumbnail image: Poly glycidyl methacrylatecoethylene dimethacrylate porous monolith as a versatile platform for the development of separations and solidphase extractions in sequential injection analyzers

The role of mass spectrometry in studies of glycation processes and diabetes management

Published: Nov 13, 2018

Author(s): Sara D'Aronco, Sara Crotti, Marco Agostini, Pietro Traldi, Nino Cristiano Chilelli, Annunziata Lapolla

Journal: Mass Spectrometry Reviews

In the last decade, mass spectrometry has been widely employed in the study of diabetes. This was mainly due to the development of new, highly sensitive, and specific methods representing powerful tools to go deep into the biochemical and pathogenetic processes typical of the disease. The aim of this review is to give a panorama of the scientifically valid results obtained in this contest. The recent studies on...

Read More thumbnail image: The role of mass spectrometry in studies of glycation processes and diabetes management

Meldonium long‐term excretion period and pharmacokinetics in blood and urine of healthy athlete volunteers

Published: Nov 12, 2018

Author(s): Olivier Rabin, Vladimir Uiba, Yulia Miroshnikova, Maksim Zabelin, Aleksander Samoylov, Vladislav Karkischenko, Sergey Semyonov, Tatiana Astrelina, Sergey Razinkin

Journal: Drug Testing and Analysis

Abstract Meldonium is a metabolic drug whose inclusion in the 2016 List of Prohibited Substances and Methods followed the analysis of data collected under the 2015 World Anti‐Doping Agency Monitoring Program. In the early months of 2016, anti‐doping laboratories reported an unusually high number of cases in which urine samples contained high concentrations of meldonium. Consequently, the meldonium excretion period in healthy...

Read More thumbnail image: Meldonium longterm excretion period and pharmacokinetics in blood and urine of healthy athlete volunteers

Worldwide distribution of blood values in elite track and field athletes: Biomarkers of altered erythropoiesis

Published: Nov 12, 2018

Author(s): Neil Robinson, Jonas Saugy, Frédéric Schütz, Raphael Faiss, Norbert Baume, Sylvain Giraud, Martial Saugy

Journal: Drug Testing and Analysis

Abstract For the first time, blood samples were collected in all athletes participating in a major sporting event of the International Association of Athletics Federations (IAAF) (Athletics World Championships 2011, Daegu, Korea). All variables obtained from blood analyses were incorporated into the individual blood profiles of each athlete for the so‐called athlete biological passport (ABP). This unprecedented data collection...

Read More thumbnail image: Worldwide distribution of blood values in elite track and field athletes Biomarkers of altered erythropoiesis

Cetyl‐alcohol‐reinforced hollow fiber solid/liquid‐phase microextraction and HPLC–DAD analysis of ezetimibe and simvastatin in human plasma and urine

Published: Nov 12, 2018

Author(s): Nabil N. AL‐Hashimi, Rand O. Shahin, Aqeel N. AL‐Hashimi, Ajeal M. Al Ajeal, Lubna H. Tahtamouni, Chanbasha Basheer

Journal: Biomedical Chromatography

Abstract A new cetyl‐alcohol‐reinforced hollow fiber solid/liquid‐phase microextraction (CA–HF–SLPME) followed by high‐performance liquid chromatography–diode array detection (HPLC–DAD) method was developed for simultaneous determination of ezetimibe and simvastatin in human plasma and urine samples. To prepare the CA–HF–SLPME device, the cetyl‐alcohol was immobilized into the pores of a 2.5 cm hollow fiber micro‐tube and the lumen...

Read More thumbnail image: Cetylalcoholreinforced hollow fiber solidliquidphase microextraction and HPLCDAD analysis of ezetimibe and simvastatin in human plasma and urine

Analysis of volatile components in Dalbergia cochinchinensis Pierre by a comprehensive two‐dimensional gas chromatography with mass spectrometry method using a solid‐state modulator

Published: Nov 12, 2018

Author(s): Zhangmin Xiang, Xiaotian Chen, Zhijun Zhao, Xue Xiao, Pengran Guo, Huacan Song, Xi Yang, Minghua Huang

Journal: Journal of Separation Science

Abstract Volatile components in Dalbergia cochinchinensis Pierre were analysed using a comprehensive two‐dimensional gas chromatography with mass spectrometry method featuring a new solid‐state modulator. Compared to one‐dimensional gas chromatography, the number of detected peaks were significantly increased. A total of 45 major compounds were identified in this study and the forward and reverse match factors of these compounds were both ...

Read More thumbnail image: Analysis of volatile components in Dalbergia cochinchinensis Pierre by a comprehensive twodimensional gas chromatography with mass spectrometry method using a solidstate modulator

A stable mesoporous metal‐organic framework as highly efficient sorbent of dispersive micro solid‐phase extraction for the determination of polycyclic aromatic hydrocarbons by HPLC

Published: Nov 12, 2018

Author(s): Lian Xia, Lijie Liu, Yanan Dou, Lan Guo, Guoliang Li, Zhiwei Sun, Jinmao You

Journal: Journal of Separation Science

Abstract Owing to the large molecular sizes of polycyclic aromatic hydrocarbons, their adsorption using microporous sorbents leads to a low adsorption capacity. Here, to increase the extraction capacity and detection sensitivity of polycyclic aromatic hydrocarbons, a highly efficient dispersive micro solid‐phase extraction method was developed based on a stable mesoporous metal‐organic framework named Jilin University China 48....

Read More thumbnail image: A stable mesoporous metalorganic framework as highly efficient sorbent of dispersive micro solidphase extraction for the determination of polycyclic aromatic hydrocarbons by HPLC
Page:   1 2 3 4 5 6 Next

Social Links

Share This Links

Bookmark and Share

Microsites

Suppliers Selection
Societies Selection

Banner Ad

Click here to see
all job opportunities

Most Viewed

Copyright Information

Interested in separation science? Visit our sister site separationsNOW.com

Copyright © 2018 John Wiley & Sons, Inc. All Rights Reserved