EarlyView Articles

Skip to Navigation

The very latest articles from the scientific literature
on Wiley Online Library...


You can keep up-to date on these EarlyView articles, which focus on spectroscopy
and separation science:

Earlyview RSS Feed

rss

Filter by Journal

Browse By Journal

Organellar Omics—A Reviving Strategy to Untangle the Biomolecular Complexity of the Cell

Published: Dec 14, 2017

Author(s): Arun Kumar Tharkeshwar, Kris Gevaert, Wim Annaert

Journal: PROTEOMICS

Abstract A eukaryotic cell encompasses many membrane‐enclosed organelles, each of these holding several types of biomolecules that exhibit tremendous diversity in terms of their localization and expression. Despite the development of increasingly sensitive analytical tools, the enormous biomolecular complexity that exists within a cell cannot yet be fully resolved as low abundant molecules often remain unrecognized. Moreover, a...

Read More thumbnail image: Organellar OmicsA Reviving Strategy to Untangle the Biomolecular Complexity of the Cell

Systematic Proteomic Analysis of Protein Methylation in Prokaryotes and Eukaryotes Revealed Distinct Substrate Specificity

Published: Dec 14, 2017

Author(s): Min Zhang, Jun‐Yu Xu, Hao Hu, Bang‐Ce Ye, Minjia Tan

Journal: PROTEOMICS

Abstract The studies of protein methylation mainly focus on lysine and arginine residues due to their diverse roles in essential cellular processes from gene expression to signal transduction. Nevertheless, atypical protein methylation occurring on amino acid residues, such as glutamine and glutamic acid, is largely neglected until recently. In addition, the systematic analysis for the distribution of methylation on different amino...

Read More thumbnail image: Systematic Proteomic Analysis of Protein Methylation in Prokaryotes and Eukaryotes Revealed Distinct Substrate Specificity

Proteogenomic Re‐Annotation of Coccidioides posadasii Strain Silveira

Published: Dec 14, 2017

Author(s): Natalie M. Mitchell, Andrew L. Sherrard, Surendra Dasari, D. Mitchell Magee, Thomas E. Grys, Douglas F. Lake

Journal: PROTEOMICS

Abstract The aims of this study are to provide protein‐based evidence upon which to reannotate the genome of Coccidiodes posadasii, one of two closely related species of Coccidioides, a dimorphic fungal pathogen that causes coccidioidomycosis, also called Valley fever. Proteins present in lysates and filtrates of in vitro grown mycelia and parasitic phase spherules from C. posadasii strain Silveira are analyzed using a GeLC‐MS/MS method. Acquired spectra...

Read More thumbnail image: Proteogenomic ReAnnotation of Coccidioides posadasii Strain Silveira

An Approach to Incorporate Multi‐Enzyme Digestion into C‐TAILS for C‐Terminomics Studies

Published: Dec 14, 2017

Author(s): Yang Zhang, Qingqing Li, Jingnan Huang, Zhen Wu, Jichang Huang, Lin Huang, Yanhong Li, Juanying Ye, Xumin Zhang

Journal: PROTEOMICS

Abstract Protein C‐termini study is still a challenging task and far behind its counterpart, N‐termini study. MS based C‐terminomics study is often hampered by the low ionization efficiency of C‐terminal peptides and the lack of efficient enrichment methods. We previously optimized the C‐terminal amine‐based isotope labeling of substrates (C‐TAILS) method and identified 369 genuine protein C‐termini in Escherichia coli. A key...

Read More thumbnail image: An Approach to Incorporate MultiEnzyme Digestion into CTAILS for CTerminomics Studies

Simultaneous determination of isomeric substituted anilines by imidization with benzaldehyde and gas chromatography–mass spectrometry

Published: Dec 14, 2017

Author(s): Mengmeng Chen, Guohua Zhu, Shanshan Wang, Kezhi Jiang, Jiaxiang Xu, Jinsong Liu, Jianxiong Jiang

Journal: Journal of Separation Science

Abstract The chromatographic separation of several isomeric anilines is a challenging issue. Herein, a simple method for the simultaneous determination of four groups of isomeric primary aromatic amines, including chloroanilines, methylanilines, methoxylanilines, and dimethylanilines, was presented. In this method, all of the 15 primary aromatic amines were easily transformed into the corresponding imine derivative by treatment with...

Read More thumbnail image: Simultaneous determination of isomeric substituted anilines by imidization with benzaldehyde and gas chromatographymass spectrometry

Synthesis of thermo‐responsive bovine hemoglobin imprinted nanoparticles by combining ionic liquid immobilization with aqueous precipitation polymerization

Published: Dec 14, 2017

Author(s): Yongmei Wang, Chongchong Yang, Yan Sun, Fengtao Qiu, Yang Xiang, Guoqi Fu

Journal: Journal of Separation Science

Abstract Surface molecular imprinting over functionalized nanoparticles has proved to be an effective approach for construction of artificial nanomaterials for protein recognition. Herein, we report a strategy for synthesis of core–shell protein‐imprinted nanoparticles by the functionalization of nano‐cores with ionic liquids followed by aqueous precipitation polymerization to build thermo‐responsive imprinted polymer nano‐shells....

Read More thumbnail image: Synthesis of thermoresponsive bovine hemoglobin imprinted nanoparticles by combining ionic liquid immobilization with aqueous precipitation polymerization

Identification of proteins, drying oils, waxes and resins in the works of art micro‐samples by chromatographic and mass spectrometric techniques

Published: Dec 14, 2017

Author(s): Bartłomiej Witkowski, Anna Duchnowicz, Monika Ganeczko, Agnieszka Laudy, Tomasz Gierczak, Magdalena Biesaga

Journal: Journal of Separation Science

Abstract Simplified method for simultaneous identification of proteins, drying oils, waxes, and resins in the works‐of‐art samples was developed. Liquid chromatography with mass spectrometry and gas chromatography with mass spectrometry were used to identify natural materials most frequently encountered in historical paintings. Protein binders were extracted with ammonia and purified using miniaturized solid‐phase microextraction...

Read More thumbnail image: Identification of proteins drying oils waxes and resins in the works of art microsamples by chromatographic and mass spectrometric techniques

A review of methods for the chemical characterization of cannabis natural products

Published: Dec 14, 2017

Author(s): Allegra Leghissa, Zacariah L. Hildenbrand, Kevin A. Schug

Journal: Journal of Separation Science

Abstract Cannabis has garnered a great deal of new attention in the past couple of years in the United States due to the increasing instances of its legalization for recreational use and indications for medicinal benefit. Despite a growing number of laboratories focused on cannabis analysis, the separation science literature pertaining to the determination of cannabis natural products is still in its infancy despite the plant having...

Read More thumbnail image: A review of methods for the chemical characterization of cannabis natural products

Development of a high‐throughput method based on thin‐film microextraction using a 96‐well plate system with a cork coating for the extraction of emerging contaminants in river water samples

Published: Dec 14, 2017

Author(s): Lucas Morés, Adriana Neves Dias, Eduardo Carasek

Journal: Journal of Separation Science

Abstract In this study, a new method was developed in which a biosorbent material is used as the extractor phase in conjunction with a recently described sample preparation technique called thin‐film microextraction and a 96‐well plate system. The method was applied for the determination of emerging contaminants, such as 3‐(4‐methylbenzylidene) camphor, ethylparaben, triclocarban, and bisphenol A in water samples. The separation and...

Read More thumbnail image: Development of a highthroughput method based on thinfilm microextraction using a 96well plate system with a cork coating for the extraction of emerging contaminants in river water samples

Rapid and green determination of 58 fragrance allergens in plush toys

Published: Dec 14, 2017

Author(s): Zhijuan Wang, Qing Zhang, Haiyu Li, Qing Lv, Wan Wang, Hua Bai

Journal: Journal of Separation Science

Abstract This paper presents a simple, rapid, and green method based on a static headspace gas chromatography–mass spectrometry for determining 58 fragrance allergens in plush toys. This study is the first to meet the requirement for simultaneously determining 66 fragrances, except for eight natural extracts restricted by the European Toy Safety Directive 2009/48/EC. A minimal amount of sample (20 mg) and acetone solvent...

Read More thumbnail image: Rapid and green determination of 58 fragrance allergens in plush toys

Application of XANES spectroscopy to investigate Sb species in corroded bullets crust material oriented to evaluate the potential toxic effects in the environment

Published: Dec 13, 2017

Author(s): Marcelo Rubio, María F. Mera, Carlos A. Pérez, Flavio C. Vicentin

Journal: X-Ray Spectrometry

Lead, antimony, and other toxic metals from pellets alloy are dispersed in the soil of the shooting fields. As long as the corroding bullets are present in soil, secondary Pb and Sb phases appear in the weathering crusts being an important source of bioavailable Pb and Sb. Knowledge about the corrosion mechanism of Sb from the bullet is limited, and reports on Sb speciation in crust and soils are still scarce. Considering that Sb species...

Read More thumbnail image: Application of XANES spectroscopy to investigate Sb species in corroded bullets crust material oriented to evaluate the potential toxic effects in the environment

Simultaneous determination of kaempferol, quercetin, mangiferin, gallic acid, p ‐hydroxybenzoic acid and chlorpheniramine maleate in rat plasma after oral administration of Mang‐Guo‐Zhi‐Ke tablets by UHPLC‐MS/MS and its application to pharmacokinetics

Published: Dec 13, 2017

Author(s): Weijie Xu, Jiagang Deng, Yiyun Qian, Xiao‐Tao Hou, Zhenhua Zhu, Ming Zhao, Erxin Shang, Dawei Qian, Huiting Zeng, Hanqing Pang, Jinao Duan

Journal: Biomedical Chromatography

Abstract Mang‐Guo‐Zhi‐Ke tablets (MGZKTs) is an effective Chinese patent medicine. It contains mango leaf extract as the main raw material and the antihistamine drug, chlorpheniramine maleate is included in the formulation. However, its pharmacokinetic effect is rarely reported. A highly sensitive, reliable and rapid high‐throughput method using ultra‐high‐performance liquid chromatography with tandem mass spectrometry (UHPLC‐MS/MS)...

Read More thumbnail image: Simultaneous determination of kaempferol quercetin mangiferin gallic acid p hydroxybenzoic acid and chlorpheniramine maleate in rat plasma after oral administration of MangGuoZhiKe tablets by UHPLCMSMS and its application to pharmacokinetics

Multiple consecutive recapture of rigid nanoparticles using a solid‐state nanopore sensor

Published: Dec 13, 2017

Author(s): Jung Soo Lee, Bin Peng, Ahmet C. Sabuncu, Seungjin Nam, ChiWon Ahn, Moon J. Kim, MinJun Kim

Journal: ELECTROPHORESIS

Abstract Solid‐state nanopore sensors have been used to measure the size of a nanoparticle by applying a resistive pulse sensing technique. Previously, the size distribution of the population pool could be investigated utilizing data from a single translocation, however, the accuracy of the distribution is limited due to the lack of repeated data. In this study, we characterized polystyrene nanobeads utilizing single particle...

Read More thumbnail image: Multiple consecutive recapture of rigid nanoparticles using a solidstate nanopore sensor

Development and validation of an ultrahigh performance liquid chromatography‐high resolution tandem mass spectrometry quantification method for hypoglycin A and methylene cyclopropyl acetic acid carnitine in horse serum in cases of atypical myopathy

Published: Dec 12, 2017

Author(s): Wiebke Rudolph, Daniela Remane, Dirk K. Wissenbach, Carmen Klein, Dirk Barnewitz, Frank T. Peters

Journal: Drug Testing and Analysis

Abstract Atypical myopathy (AM) is a fatal disease in horses presumably caused by hypoglycine A (HGA) from ingested maple seeds and its active metabolite methylene cyclopropyl acetic acid (MCPA). The aim of this study was the development and validation of a rapid and simple assay for HGA and MCPA‐carnitine in horse serum and its application to authentic samples. Identification and quantification were carried out by ultra high...

Read More thumbnail image: Development and validation of an ultrahigh performance liquid chromatographyhigh resolution tandem mass spectrometry quantification method for hypoglycin A and methylene cyclopropyl acetic acid carnitine in horse serum in cases of atypical myopathy

Chromatographic analysis of VOC patterns in exhaled breath from smokers and nonsmokers

Published: Dec 12, 2017

Author(s): Simonetta Capone, Maria Tufariello, Angiola Forleo, Valentina Longo, Lucia Giampetruzzi, Antonio Vincenzo Radogna, Flavio Casino, Pietro Siciliano

Journal: Biomedical Chromatography

Abstract Cigarette smoking harms nearly every organ of the body and causes many diseases. The analysis of exhaled breath for exogenous and endogenous volatile organic compounds (VOCs) can provide fundamental information on active smoking and insight into the health damage that smoke is creating. Various exhaled VOCs have been reported as typical of smoking habit and recent tobacco consumption, but to date, no eligible biomarkers...

Read More thumbnail image: Chromatographic analysis of VOC patterns in exhaled breath from smokers and nonsmokers

Comprehensive analysis of nine monoamines and metabolites in small amounts of peripheral murine (C57Bl/6 J) tissues

Published: Dec 12, 2017

Author(s): Joachim Nagler, Sonja C. Schriever, Meri De Angelis, Paul T. Pfluger, Karl‐Werner Schramm

Journal: Biomedical Chromatography

Abstract Monoamines, acting as hormones and neurotransmitters, play a critical role in multiple physiological processes ranging from cognitive function and mood to sympathetic nervous system activity, fight‐or‐flight response and glucose homeostasis. In addition to brain and blood, monoamines are abundant in several tissues, and dysfunction in their synthesis or signaling is associated with various pathological conditions. It was...

Read More thumbnail image: Comprehensive analysis of nine monoamines and metabolites in small amounts of peripheral murine C57Bl6J tissues

Screening and identification of potential hypoglycemic components in Zeng Ye Tang by high‐performance liquid chromatography coupled with tandem quadrupole time‐of‐flight mass spectrometry

Published: Dec 12, 2017

Author(s): Yu Shan Tian, Zhong Ying Du, Ying Xiao, BoYang Yu, Jin Qi

Journal: Journal of Separation Science

Abstract Zeng Ye Tang, a famous prescription consisting of Xuanshen, Maidong, and Shengdi (5:4:4), has been used in China for a long time to treat diabetes caused by excessive heat with yin deficiency. Although many studies have investigated the pharmacological effects of Zeng Ye Tang, the compounds responsible for its hypoglycemic effect have not been identified. In this study, 50 compounds in Zeng Ye Tang were identified by high‐performance liquid...

Read More thumbnail image: Screening and identification of potential hypoglycemic components in Zeng Ye Tang by highperformance liquid chromatography coupled with tandem quadrupole timeofflight mass spectrometry

Gold film over very small (107 nm) spheres as efficient substrate for sensitive and reproducible surface‐enhanced Raman scattering (SERS) detection of biologically important molecules

Published: Dec 11, 2017

Author(s): Lucie Štolcová, Vlastimil Peksa, Jan Proška, Marek Procházka

Journal: Journal of Raman Spectroscopy

Abstract Gold plasmonic nanostructures with high sensitivity and spectral reproducibility are key components of molecular sensors based on surface‐enhanced Raman scattering (SERS). In this paper, we report a “bottom‐up” fabrication of gold “film over nanosphere” (FON) substrates for SERS sensing on the basis of very small (107 nm in diameter) polystyrene spheres coated with 20 nm of gold. To obtain close‐packed spheres in...

Read More thumbnail image: Gold film over very small 107nm spheres as efficient substrate for sensitive and reproducible surfaceenhanced Raman scattering SERS detection of biologically important molecules

Relationship between Raman spectral features and fugacity in mixtures of gases

Published: Dec 11, 2017

Author(s): Hector M. Lamadrid, Matthew Steele‐MacInnis, Robert J. Bodnar

Journal: Journal of Raman Spectroscopy

Abstract Raman spectroscopy yields information about the internal vibrational modes of covalently bonded molecules, which are sensitive to the local molecular environment. As such, Raman spectra of a gas composed of covalently bonded molecules collected at different temperatures and/or pressures show variations in band positions and other spectral features, reflecting molecular‐scale interactions (attraction and repulsion) among gas...

Read More thumbnail image: Relationship between Raman spectral features and fugacity in mixtures of gases

10 years of Drug Testing and Analysis

Published: Dec 11, 2017

Author(s): Paul Trevorrow

Journal: Drug Testing and Analysis

Read More thumbnail image: 10 years of Drug Testing and Analysis
Page:   1 2 3 4 5 6 Next

Social Links

Share This Links

Bookmark and Share

Microsites

Suppliers Selection
Societies Selection

Banner Ad

Click here to see
all job opportunities

Most Viewed

Copyright Information

Interested in separation science? Visit our sister site separationsNOW.com

Copyright © 2017 John Wiley & Sons, Inc. All Rights Reserved