EarlyView Articles

Skip to Navigation

The very latest articles from the scientific literature
on Wiley Online Library...


You can keep up-to date on these EarlyView articles, which focus on spectroscopy
and separation science:

Earlyview RSS Feed

rss

Filter by Journal

Browse By Journal

The metabolism of flubendazole in human liver and cancer cell lines

Published: Mar 22, 2018

Author(s): Lucie Raisová Stuchlíková, Věra Králová, Kateřina Lněničková, Tomáš Zárybnický, Petra Matoušková, Veronika Hanušová, Martin Ambrož, Zdeněk Šubrt, Lenka Skálová

Journal: Drug Testing and Analysis

Abstract Flubendazole (FLU), a benzimidazole anthelmintic drug widely used in veterinary medicine, has been approved for the treatment of gut‐residing nematodes in humans. In addition, FLU is now considered a promising anti‐cancer agent. Despite this, information about biotransformation of this compound in human is lacking. Moreover, there is no information regarding whether cancer cells are able to metabolize FLU in order to...

Read More thumbnail image: The metabolism of flubendazole in human liver and cancer cell lines

Sequential interfacial reactions of SAC305 solder joints with thin ENEPIG surface finishes

Published: Mar 22, 2018

Author(s): Jeong‐Won Yoon, Jong‐Hoon Back, Seung‐Boo Jung

Journal: Surface and Interface Analysis

Sequential interfacial reactions of Sn‐3.0Ag‐0.5Cu solder on a new multilayer metallization, ENEPIG (electroless nickel‐electroless palladium‐immersion gold) with a 0.1‐μm‐thin Ni(P) layer (thin‐ENEPIG), during reflowing were evaluated in this study. After 20‐second reflow process, layer‐shaped (Au,Cu)Sn4 intermetallic compounds formed at the interface, and thin Ni and Pd layers underneath the Au layer remained unreacted on the...

Read More thumbnail image: Sequential interfacial reactions of SAC305 solder joints with thin ENEPIG surface finishes

The impact of the diamond reinforcing particle size on their interaction with the aluminum matrix of composites in the course of heating

Published: Mar 22, 2018

Author(s): Vladimir Popov

Journal: Surface and Interface Analysis

In aluminum matrix composites, the formation of aluminum carbide may occur during heating on contact between aluminum and the carbon reinforcing particles. Samples of composites with an aluminum matrix and various diamond reinforcing particles were prepared to determine the influence of the size of the diamond particles on this process. The composites were obtained via mechanical alloying. Annealing shows that the outcome is different for...

Read More thumbnail image: The impact of the diamond reinforcing particle size on their interaction with the aluminum matrix of composites in the course of heating

XPS study during a soft and progressive sputtering of a monolayer on indium phosphide by argon cluster bombardment

Published: Mar 22, 2018

Author(s): Damien Aureau, Mathieu Frégnaux, Christian Njel, Jackie Vigneron, Muriel Bouttemy, Anne‐Marie Gonçalves, Arnaud Etcheberry

Journal: Surface and Interface Analysis

Gas cluster ion beam is performed on an ultrathin “polyphosphazene‐like” film grown on indium phosphide substrates to obtain crucial properties of this model system. Unlike “standard” sputtering technique using monoatomic ions, a gentle progressive digging of this subnanometric thick layer has been realized thanks to the unique depth profiling features of gas cluster ion beam. Furthermore, our results highlight the properties of the...

Read More thumbnail image: XPS study during a soft and progressive sputtering of a monolayer on indium phosphide by argon cluster bombardment

ANOVA tables and statistical significance of models

Published: Mar 14, 2018

Author(s): Richard G. Brereton

Journal: Journal of Chemometrics

Read More thumbnail image: ANOVA tables and statistical significance of models

Introduction to analysis of variance

Published: Mar 14, 2018

Author(s): Richard G. Brereton

Journal: Journal of Chemometrics

Read More thumbnail image: Introduction to analysis of variance

Sources of error

Published: Mar 14, 2018

Author(s): Richard G. Brereton

Journal: Journal of Chemometrics

Read More thumbnail image: Sources of error

Membranal and Blood‐Soluble HLA Class II Peptidome Analyses Using Data‐Dependent and Independent Acquisition

Published: Mar 14, 2018

Author(s): Danilo Ritz, Emiliano Sani, Hanna Debiec, Pierre Ronco, Dario Neri, Tim Fugmann

Journal: PROTEOMICS

Abstract The interaction between HLA class II peptide complexes on antigen‐presenting cells and CD4+ T cells is of fundamental importance for anticancer and antipathogen immunity as well as for the maintenance of immunological tolerance. To study CD4+ T cell reactivities, detailed knowledge of the presented peptides is necessary. In recent years, dramatic advances in the characterization of membranal and soluble HLA class I peptidomes could be...

Read More thumbnail image: Membranal and BloodSoluble HLA Class II Peptidome Analyses Using DataDependent and Independent Acquisition

Establishing the optimal blocks' order in SO‐PLS: Stepwise SO‐PLS and alternative formulations

Published: Mar 13, 2018

Author(s): Maria P. Campos, Ricardo Sousa, Marco S. Reis

Journal: Journal of Chemometrics

Abstract Methods capable of handling multiple blocks of data have increased in popularity both in industry and academia, namely, in the fields of chemistry, food and beverages, pharmacology, and biology. Among the multiblock methodologies, sequential orthogonalized partial least squares (SO‐PLS) has been attracting great interest, given its interpretation capabilities (eg, the possibility to estimate the relative additional...

Read More thumbnail image: Establishing the optimal blocks order in SOPLS Stepwise SOPLS and alternative formulations

Cross‐linked peptide identification: A computational forest of algorithms

Published: Mar 12, 2018

Author(s): Şule Yılmaz, Genet A. Shiferaw, Josep Rayo, Anastassios Economou, Lennart Martens, Elien Vandermarliere

Journal: Mass Spectrometry Reviews

Chemical cross‐linking analyzed by mass spectrometry (XL‐MS) has become an important tool in unravelling protein structure, dynamics, and complex formation. Because the analysis of cross‐linked proteins with mass spectrometry results in specific computational challenges, many computational tools have been developed to identify cross‐linked peptides from mass spectra and subsequently interpret the identified...

Read More thumbnail image: Crosslinked peptide identification A computational forest of algorithms

Process‐centric and data‐centric strategies for enhanced production of l ‐asparaginase—an anticancer enzyme, using marine‐derived Aspergillus niger

Published: Mar 12, 2018

Author(s): Anjana K. Vala, Dushyant R. Dudhagara, Bharti P. Dave

Journal: Journal of Chemometrics

Abstract The objective of the study was to achieve enhanced production of l‐asparaginase (LA), an anticancer enzyme, by a marine‐derived Aspergillus niger isolate. To improve LA production, optimization of pH, incubation time, and inoculum size was performed using process‐centric (response surface methodology [RSM]) and data‐centric (artificial neural network [ANN]) approaches. The optimized conditions led to a 108.62% rise in LA production....

Read More thumbnail image: Processcentric and datacentric strategies for enhanced production of l asparaginasean anticancer enzyme using marinederived Aspergillus niger

Glycosphingolipidomics of donkey milk by hydrophilic interaction liquid chromatography coupled to ESI and multistage MS

Published: Mar 12, 2018

Author(s): Cosima Damiana Calvano, Marco Glaciale, Francesco Palmisano, Tommaso R.I. Cataldi

Journal: ELECTROPHORESIS

Abstract Hydrophilic interaction liquid chromatography coupled to negative‐ion electrospray linear ion‐trap multiple‐stage MS (HILIC‐ESI‐MSn, n = 2,3) was used to characterize polar lipids occurring in donkey milk. Besides the detection of abundant phospholipids, the structural characterization and content evaluation of minor glycosphingolipids (GSLs) were assessed. We report an unprecedented characterization of 11 hexosyl‐ceramides...

Read More thumbnail image: Glycosphingolipidomics of donkey milk by hydrophilic interaction liquid chromatography coupled to ESI and multistage MS

Molecular imprinted polymers based on magnetic chitosan with different deep eutectic solvent monomers for the selective separation of catechins in black tea

Published: Mar 9, 2018

Author(s): Wanwan Ma, Yunliang Dai, Kyung Ho Row

Journal: ELECTROPHORESIS

Abstract Two types of molecular‐imprinted polymers‐based magnetic chitosan with facile deep eutectic solvent‐functional monomers (Fe3O4‐CTS@DES‐MIPs) were synthesized and applied as adsorbents in magnetic solid‐phase extraction (MSPE) for the selective recognition and separation of (+)‐catechin, (−)‐epicatechin, and (−)‐epigallocatechin gallate in black tea. The obtained Fe3O4‐CTS@DES‐MIPs were characterized by Fourier transform infrared spectroscopy and...

Read More thumbnail image: Molecular imprinted polymers based on magnetic chitosan with different deep eutectic solvent monomers for the selective separation of catechins in black tea

Continuous sheath‐free separation of drug‐treated human fungal pathogen Cryptococcus neoformans by morphology in biocompatible polymer solutions

Published: Mar 9, 2018

Author(s): Di Li, Jessica Zielinski, Lukasz Kozubowski, Xiangchun Xuan

Journal: ELECTROPHORESIS

Abstract Cryptococcal meningitis caused by Cryptococcus neoformans is the leading cause of fungal central nervous system infections. Current antifungal treatments for cryptococcal infections are inadequate partly due to the occurrence of drug resistance. Recent studies indicate that the treatment of the azole drug fluconazole changes the morphology of C. neoformans to form enlarged “multimeras” that consist of three or more connected...

Read More thumbnail image: Continuous sheathfree separation of drugtreated human fungal pathogen Cryptococcus neoformans by morphology in biocompatible polymer solutions

Control of functionalization of supports for subsequent assembly of t itania nanoparticle films

Published: Mar 9, 2018

Author(s): Steffi Rades, Patrizia Borghetti, Erik Ortel, Thomas Wirth, Miren Blanco, Estíbaliz Gómez, Amaia Martinez, Jacques Jupille, Gianmario Martra, Vasile‐Dan Hodoroaba

Journal: Surface and Interface Analysis

For self‐assembling of TiO2 nanoparticles in multiple layers by layer‐by‐layer deposition to be applied to TiO2 thin films with defined and homogeneous thickness for large‐scale applications, the proper functionalization of substrate surface is a prerequisite to guarantee sufficient adhesion. The substrates selected and tested in the present paper were conductive, fluorine‐doped tin oxide (FTO) glass, nonconductive silica glass, and titanium alloy....

Read More thumbnail image: Control of functionalization of supports for subsequent assembly of t itania nanoparticle films

Analytical approach for characterization of morphology and chemistry of a CH 3 NH 3 PbI 3 /TiO 2 solar cell layered system

Published: Mar 9, 2018

Author(s): Steffi Rades, Frederic Oswald, Stephanie Narbey, Jörg Radnik, Vasile‐Dan Hodoroaba

Journal: Surface and Interface Analysis

Manufacturing of new perovskite layered solar cells with constant high light conversion efficiency over time may be hampered by the loss of efficiency caused by structural and/or chemical alterations of the complex layered system. SEM/EDX combined with XPS were chosen as an appropriate methodical approach to characterize perovskite laboratory cells in depth and at surface, before and after light exposure. The layered perovskite system...

Read More thumbnail image: Analytical approach for characterization of morphology and chemistry of a CH 3 NH 3 PbI 3 TiO 2 solar cell layered system

Simulation of kinetic behavior of natural surfactants adsorption using a new robust approach

Published: Mar 9, 2018

Author(s): Navid Daryasafar, Omid Borazjani, Amin Daryasafar

Journal: Journal of Chemometrics

Abstract Surfactant‐based enhanced oil recovery techniques are known as promising methods for mobilizing the trapped oil in porous media. Surfactants can improve oil recovery by modifying the wettability of rock minerals and also by reducing the interfacial tension between injected water and the trapped oil. Natural surfactants have been introduced as good candidates for enhanced oil recovery applications. In addition, they are less...

Read More thumbnail image: Simulation of kinetic behavior of natural surfactants adsorption using a new robust approach

Scanning A uger spectromicroscopy using the S cope F oundry software platform

Published: Mar 9, 2018

Author(s): Daniel B. Durham, D. Frank Ogletree, Edward S. Barnard

Journal: Surface and Interface Analysis

We have developed an open‐source, Python‐based software platform called ScopeFoundry for performing complex, multidimensional microscopy experiments that integrate diverse types of experimental hardware. ScopeFoundry streamlines experiment development by providing a modular environment where hardware controls and measurement schemes can be arranged and customized. Important software tasks such as data management and user interface...

Read More thumbnail image: Scanning A uger spectromicroscopy using the S cope F oundry software platform

In Immunopeptidomics We Need a Sniper Instead of a Shotgun

Published: Mar 7, 2018

Author(s): Pouya Faridi, Anthony Wayne Purcell, Nathan Paul Croft

Journal: PROTEOMICS

Abstract Immunopeptidomics employs the use of mass spectrometry to identify and quantify peptides presented on the surface of cells by major histocompatibility complex (MHC; human leukocyte antigen [HLA], in humans) molecules, an essential component of adaptive immunity. Currently, immunopeptidomics follows the same or similar workflows as the more established field of shotgun proteomics, yet inherent differences between these two...

Read More thumbnail image: In Immunopeptidomics We Need a Sniper Instead of a Shotgun

High‐throughput statistical screening of antiinfective peptides from natural antibacterial protein repertoire: Chemometric prediction, molecular modeling, and susceptibility analysis

Published: Mar 7, 2018

Author(s): Guangmei Sun, Liyun Leng, Xiaocui Wang

Journal: Journal of Chemometrics

Abstract Antibiotic‐resistant bacterial infection (ARBI) is one of the most serious global public health threats. Antiinfective peptides (AIPs) have been recognized as a promising alternative to traditional antibiotics, which can effectively combat the ARBI in a distinct mechanism. In the current study, we attempt to discover new and potent AIPs from the natural antibacterial protein repertoire. Hundreds of antibacterial proteins...

Read More thumbnail image: Highthroughput statistical screening of antiinfective peptides from natural antibacterial protein repertoire Chemometric prediction molecular modeling and susceptibility analysis
Page:   Prev 15 16 17 18 19 20 21 22 23 24 25 Next

Social Links

Share This Links

Bookmark and Share

Microsites

Suppliers Selection
Societies Selection

Banner Ad

Click here to see
all job opportunities

Most Viewed

Copyright Information

Interested in separation science? Visit our sister site separationsNOW.com

Copyright © 2018 John Wiley & Sons, Inc. All Rights Reserved