EarlyView Articles

Skip to Navigation

The very latest articles from the scientific literature
on Wiley Online Library...


You can keep up-to date on these EarlyView articles, which focus on spectroscopy
and separation science:

Earlyview RSS Feed

rss

Filter by Journal

Browse By Journal

Cluster versus ROI analysis to assess combined antiangiogenic therapy and radiotherapy in the F98 rat‐glioma model

Published: Jun 4, 2018

Author(s): Nicolas Coquery, Raphael Serduc, Chantal Rémy, Emmanuel Luc Barbier, Benjamin Lemasson

Journal: NMR in Biomedicine

For glioblastoma (GBM), current therapeutic approaches focus on the combination of several therapies, each of them individually approved for GBM or other tumor types. Many efforts are made to decipher the best sequence of treatments that would ultimately promote the most efficient tumor response. There is therefore a strong interest in developing new clinical in vivo imaging procedures that can rapidly detect treatment efficacy and allow individual...

Read More thumbnail image: Cluster versus ROI analysis to assess combined antiangiogenic therapy and radiotherapy in the F98 ratglioma model

Ex vivo diffusion MRI of the human brain: Technical challenges and recent advances

Published: Jun 4, 2018

Author(s): Alard Roebroeck, Karla L. Miller, Manisha Aggarwal

Journal: NMR in Biomedicine

This review discusses ex vivo diffusion magnetic resonance imaging (dMRI) as an important research tool for neuroanatomical investigations and the validation of in vivo dMRI techniques, with a focus on the human brain. We review the challenges posed by the properties of post‐mortem tissue, and discuss state‐of‐the‐art tissue preparation methods and recent advances in pulse sequences and acquisition techniques to tackle these. We then...

Read More thumbnail image: Ex vivo diffusion MRI of the human brain Technical challenges and recent advances

An adaptive denoising method for Raman spectroscopy based on lifting wavelet transform

Published: Jun 4, 2018

Author(s): Hao Chen, Weiliang Xu, Neil Broderick, Jianda Han

Journal: Journal of Raman Spectroscopy

Abstract Noise, especially high‐level noise, is a severe problem in Raman spectral analysis. It smears informative Raman peaks, distorts spectral features, and therefore affects final analytical results, particularly in multivariate analysis, which is frequently used in Raman spectroscopy. This becomes even worse when it comes to optical Raman probe‐based biological applications due to limited acquisition time, laser power, and...

Read More thumbnail image: An adaptive denoising method for Raman spectroscopy based on lifting wavelet transform

A review of orthogonal projections for calibration

Published: Jun 4, 2018

Author(s): Jean‐Michel Roger, Jean‐Claude Boulet

Journal: Journal of Chemometrics

Abstract Effective methods often rely on simple mathematical operators. Among these operators, orthogonal projections have been widely used because of their simplicity in compensating for detrimental factors. This efficiency depends largely on the way these tools are prepared. This article links the mathematical basics of orthogonal projections to the notion of vectoral subspaces, highlighting which information should be removed in...

Read More thumbnail image: A review of orthogonal projections for calibration

A bioinspired polydopamine approach toward the preparation of gold‐modified magnetic nanoparticles for the magnetic solid‐phase extraction of steroids in multiple samples

Published: Jun 3, 2018

Author(s): Xuehan An, Weibo Chai, Xiaojuan Deng, Hui Chen, Guosheng Ding

Journal: Journal of Separation Science

Abstract In this work, a simple, facile, and sensitive magnetic solid‐phase extraction method was developed for the extraction and enrichment of three representative steroid hormones before high‐performance liquid chromatography analysis. Gold‐modified Fe3O4 nanoparticles, as novel magnetic adsorbents, were prepared by a rapid and environmentally friendly procedure in which polydopamine served as the reductant as well as the...

Read More thumbnail image: A bioinspired polydopamine approach toward the preparation of goldmodified magnetic nanoparticles for the magnetic solidphase extraction of steroids in multiple samples

Comparative gel‐based proteomic analysis of chemically crosslinked complexes in dystrophic skeletal muscle

Published: Jun 1, 2018

Author(s): Sandra Murphy, Margit Zweyer, Rustam R. Mundegar, Dieter Swandulla, Kay Ohlendieck

Journal: ELECTROPHORESIS

Abstract Duchenne muscular dystrophy is a highly progressive muscle wasting disease with a complex pathophysiology that is based on primary abnormalities in the dystrophin gene. In order to study potential changes in the oligomerization of high‐molecular‐mass protein complexes in dystrophic skeletal muscle, chemical crosslinking was combined with mass spectrometric analysis. The biochemical stabilization of protein interactions was...

Read More thumbnail image: Comparative gelbased proteomic analysis of chemically crosslinked complexes in dystrophic skeletal muscle

Microchip electrophoresis separation of a panel of preterm birth biomarkers

Published: Jun 1, 2018

Author(s): Anna V. Nielsen, Jacob B. Nielsen, Mukul Sonker, Radim Knob, Vishal Sahore, Adam T. Woolley

Journal: ELECTROPHORESIS

Abstract Preterm birth (PTB) is responsible for over one million infant deaths annually worldwide. Often, the first and only indication of PTB risk is the onset of early labor. Thus, there is an urgent need for an early PTB risk diagnostic that is inexpensive, reliable, and robust. Here, we describe the development of a microchip electrophoresis (μCE) method for separating a mixture of six PTB protein and peptide biomarkers present...

Read More thumbnail image: Microchip electrophoresis separation of a panel of preterm birth biomarkers

Sequence‐based US population data for the SE33 locus

Published: Jun 1, 2018

Author(s): Lisa A. Borsuk, Katherine B. Gettings, Carolyn R. Steffen, Kevin M. Kiesler, Peter M. Vallone

Journal: ELECTROPHORESIS

Abstract A set of 1036 U.S. Population Samples were sequenced using the Illumina ForenSeq DNA Signature Prep Kit. This sample set has been highly characterized using a variety of marker systems for human identification. The FASTQ files obtained from a ForenSeq DNA Signature Prep Kit experiment include several STR loci that are not reported in the associated software. These include SE33, DXS8377, DXS10148, DYS456, and DYS461. The...

Read More thumbnail image: Sequencebased US population data for the SE33 locus

Testing the ab initio quantum‐scattering calculations for the D 2 –He benchmark system with stimulated Raman spectroscopy

Published: Jun 1, 2018

Author(s): Raúl Z. Martínez, Dionisio Bermejo, Franck Thibault, Piotr Wcisło

Journal: Journal of Raman Spectroscopy

Abstract This work presents a comparison between experimental and calculated values for the collisional line broadenings and shifts of the S0(0), S0(1), and S0(2) lines of the rotational Raman spectrum of D2 perturbed by He at 77, 195, and 300 K. The pure rotational Raman spectra were obtained by means of a stimulated Raman spectroscopy experimental setup. Close coupling dynamical calculations were performed on the most recent ab initio...

Read More thumbnail image: Testing the ab initio quantumscattering calculations for the D 2 He benchmark system with stimulated Raman spectroscopy

Preparation, intercalation, and characterization of nanostructured (Zn, Al) layered double hydroxides (LDHs)

Published: Jun 1, 2018

Author(s): M. Richetta, A. Varone, A. Mattoccia, P.G. Medaglia, S. Kaciulis, A. Mezzi, P. Soltani, R. Pizzoferrato

Journal: Surface and Interface Analysis

The term layered double hydroxides (LDHs) is used to define synthetic or natural lamellar hydroxides with 2 or more kinds of metallic cations in the main layers, and hydrated interlayer domains, containing anionic species. Layered double hydroxides, also known as hydrotalcite materials, have attracted considerable interest from both industry and academia. They are interesting for their intercalation properties as they are capable of...

Read More thumbnail image: Preparation intercalation and characterization of nanostructured Zn Al layered double hydroxides LDHs

Theoretical and experimental approach of inhibition effect by sulfamethoxazole on mild steel corrosion in 1‐M HCl

Published: Jun 1, 2018

Author(s): B.M. Prasanna, B.M. Praveen, Narayan Hebbar, M.K. Pavithra, T.S. Manjunatha, R.S. Malladi

Journal: Surface and Interface Analysis

The inhibition effect of sulfamethoxazole on mild steel corrosion in 1‐M hydrochloric acid solution is investigated by electrochemical and quantum chemical measurements. Electrochemical polarization studies show that sulfamethoxazole acts as a mixed‐type corrosion inhibitor. The adsorption of the inhibitor on mild steel in 1‐M hydrochloric acid system is studied at different temperatures (303‐333 K). The adsorption of...

Read More thumbnail image: Theoretical and experimental approach of inhibition effect by sulfamethoxazole on mild steel corrosion in 1M HCl

Effects of surface synergy for the dispersion of short carbon fibers sized by adipic acid modified epoxy resin potassium

Published: Jun 1, 2018

Author(s): Bo Wu, Guo Zheng, Rui Wang, Cun Zhou, Jiawen Zhu, Huibing Liu

Journal: Surface and Interface Analysis

The carbon fiber (CF) surface plays a critical role in the performance of CF composite materials. Adipic acid modified epoxy resin potassium (AAEK) prepared with epoxy resin and adipic acid, and KOH was employed as the CF sizing agent. Then, series of surface properties of AAEK‐treated carbon fiber (CF‐AAEK) including surface charge, morphology, and groups were characterized by using Faraday cup, friction coefficient gauge, atomic force...

Read More thumbnail image: Effects of surface synergy for the dispersion of short carbon fibers sized by adipic acid modified epoxy resin potassium

The expanding role of mass spectrometry in the field of vaccine development

Published: May 31, 2018

Author(s): Vaneet Kumar Sharma, Ity Sharma, James Glick

Journal: Mass Spectrometry Reviews

Biological mass spectrometry has evolved as a core analytical technology in the last decade mainly because of its unparalleled ability to perform qualitative as well as quantitative profiling of enormously complex biological samples with high mass accuracy, sensitivity, selectivity and specificity. Mass spectrometry‐based techniques are also routinely used to assess glycosylation and other post‐translational...

Read More thumbnail image: The expanding role of mass spectrometry in the field of vaccine development

An effect of residual gas component on detected secondary ions during TOF‐SIMS depth profiling and a method to estimate contained component

Published: May 31, 2018

Author(s): Junichiro Sameshima, Masanobu Yoshikawa

Journal: Surface and Interface Analysis

With regard to Secondary Ion Mass Spectroscopy (SIMS) measurement of atmospheric gas elements, a problem occurs that the detected signal includes background components caused by residual gas along with contained components. Relating to this issue, an available method to quantify the contained components by separating the background ones had been established for Dynamic SIMS. Time‐of‐Flight SIMS with sputtering ion gun has also applied for...

Read More thumbnail image: An effect of residual gas component on detected secondary ions during TOFSIMS depth profiling and a method to estimate contained component

Instrumental detection limit and sensitivity of K and L shell X‐ray emission lines of 17 Cl, 37 Rb, and 38 Sr elements using PC‐WDXRF spectrometer

Published: May 31, 2018

Author(s): Harpreet Singh Kainth, Tejbir Singh, Jangvir Singh Shahi, Devinder Mehta, Sanjeev Kumar

Journal: X-Ray Spectrometry

This work was aimed to improve the instrumental detection limit and sensitivity of 17Cl, 37Rb, and 38Sr elements present in solid samples by using the advanced polychromatic wavelength dispersive X‐ray fluorescence spectrometry method. Instrumental measuring parameters, as well as study of calibration curves of K and L shell spectral lines, were evaluated to select the best conditions for 17Cl, 37Rb, and 38Sr quantification. From the results, it was observed...

Read More thumbnail image: Instrumental detection limit and sensitivity of K and L shell Xray emission lines of 17 Cl 37 Rb and 38 Sr elements using PCWDXRF spectrometer

Development and validation of an HPLC‐UV method for quantification of elvitegravir and two other new antiretrovirals, dolutegravir and rilpivirine, in the plasma of HIV‐positive patients

Published: May 31, 2018

Author(s): Massimo Tempestilli, Adriana Ammassari, Antonio D'Avolio, Stefania Cicalini, Anna Loredana Gallo, Simone Fazio, Andrea Antinori, Leopoldo P. Pucillo

Journal: Biomedical Chromatography

Abstract Therapeutic drug monitoring may be crucial in selected clinical conditions for the management of HIV infection. In recent years, new antiretrovirals have been introduced and in particular elvitegravir (EVG) is now recommended for first‐line and simplification treatment as well as dolutegravir (DTG) and rilpivirine (RPV). The aim of this study was to develop and validate a high‐performance liquid chromatography–ultraviolet...

Read More thumbnail image: Development and validation of an HPLCUV method for quantification of elvitegravir and two other new antiretrovirals dolutegravir and rilpivirine in the plasma of HIVpositive patients

The profiling and identification of chemical components, prototypes and metabolites of Run‐zao‐zhi‐yang capsule in rat plasma, urine and bile by an UPLC‐Q‐TOF/MS E ‐based high‐throughput strategy

Published: May 31, 2018

Author(s): Shan Lin, Xinyi Yue, Danwei Ouyang, Quan Li, Peiming Yang

Journal: Biomedical Chromatography

Abstract Run‐zao‐zhi‐yang (RZZY) capsule, a traditional Chinese medicine formula, is popularly used for the treatment of dermatitis and eczema. However, few studies have been carried out on RZZY and its metabolites. In this study, we developed a three‐step strategy to rapidly characterize the chemical constituents and metabolites of RZZY using ultra‐high‐performance liquid chromatography coupled with quadrupole time‐of‐flight mass...

Read More thumbnail image: The profiling and identification of chemical components prototypes and metabolites of Runzaozhiyang capsule in rat plasma urine and bile by an UPLCQTOFMS E based highthroughput strategy

Preparative isolation of ganoderic acid S, ganoderic acid T and ganoderol B from Ganoderma lucidum mycelia by high‐speed counter‐current chromatography

Published: May 31, 2018

Author(s): Na Feng, Yutian Wei, Jie Feng, Qingjiu Tang, Zhong Zhang, Jingsong Zhang, Han Wei

Journal: Biomedical Chromatography

Abstract Ganoderic acid S, ganoderic acid T and ganoderal B are the main bioactive triterpenes of Ganoderma lucidum. In this study, mycelia of G. lucidum were obtained by two‐stage fermentation and then extracted by ethanol and petroleum ether sequentially to obtain crude triterpenes. The crude sample was further purified by recycling high‐speed counter‐current chromatography with n‐hexane–ethyl acetate–methanol–water (7:12:11:5, v/v/v/v) as the optimized...

Read More thumbnail image: Preparative isolation of ganoderic acid S ganoderic acid T and ganoderol B from Ganoderma lucidum mycelia by highspeed countercurrent chromatography

Breast magnetic resonance elastography: a review of clinical work and future perspectives

Published: May 30, 2018

Author(s): A.E. Bohte, J.L. Nelissen, J.H. Runge, O. Holub, S.A. Lambert, L. Graaf, S. Kolkman, S. Meij, J. Stoker, G.J. Strijkers, A.J. Nederveen, R. Sinkus

Journal: NMR in Biomedicine

This review on magnetic resonance elastography (MRE) of the breast provides an overview of available literature and describes current developments in the field of breast MRE, including new transducer technology for data acquisition and multi‐frequency‐derived power‐law behaviour of tissue. Moreover, we discuss the future potential of breast MRE, which goes beyond its original application as an additional tool in differentiating benign...

Read More thumbnail image: Breast magnetic resonance elastography a review of clinical work and future perspectives

Separation and determination of the enantiomers of lactic acid and 2‐hydroxyglutaric acid by chiral derivatization combined with gas chromatography and mass spectrometry

Published: May 30, 2018

Author(s): Xuemei Ding, Shuhai Lin, Hongbo Weng, Jianying Liang

Journal: Journal of Separation Science

Abstract Lactic acid and 2‐hydroxyglutaric acid are chiral metabolites that have two distinct d‐ and l‐enantiomers with distinct biochemical properties. Perturbations of a single enantiomeric form have been found to be closely related to certain diseases. Therefore, the ability to differentiate the d and l enantiomers is important for these disease studies. Herein, we describe a method for the separation and determination of lactic acid and...

Read More thumbnail image: Separation and determination of the enantiomers of lactic acid and 2hydroxyglutaric acid by chiral derivatization combined with gas chromatography and mass spectrometry
Page:   Prev 2 3 4 5 6 7 8 9 10 11 12 Next

Social Links

Share This Links

Bookmark and Share

Microsites

Suppliers Selection
Societies Selection

Banner Ad

Click here to see
all job opportunities

Most Viewed

Copyright Information

Interested in separation science? Visit our sister site separationsNOW.com

Copyright © 2018 John Wiley & Sons, Inc. All Rights Reserved