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Developments in Analysis of Drugs and Metabolites in Skeletal Remains

Bone remains are one of the least characterized and most challenging matrices for forensic toxicological analysis. Before the forensic utility of the matrix may be fully realized, controlled experiments must be carried out. This presentation will highlight the value that UPLC-based approaches have brought to the drug analysis of bone samples. In addition, we will discuss the most recent findings in analytical developments using UPLC-QTof mass spectrometry, including: dramatic enhancements in sensitivity,...

Read More thumbnail image: <font color=red>Webinar<br/>Now available on-demand</font><br/>Developments in Analysis of Drugs and Metabolites in Skeletal Remains

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2017 Edition of Mass Spectra of Designer Drugs

thumbnail image: <font size=3>2017 Edition of Mass Spectra of Designer Drugs</font>

Available now from Wiley and Wiley-VCH, the 2017 edition of Mass Spectra of Designer Drugs

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Ezines

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A systematic review of published reports on proteomic biomarkers identified in systemic lupus erythematosus patients using mass spectrometry-based proteomics has been conducted, highlighting their potential disease association and clinical utility.

A review is presented of the major building blocks of the pipeline toward performing quantitative analysis of in vivo MRI of the developing brain and its potential applications in clinical settings.

Morphine addiction: Enzyme activity

Steve Down

May 16, 2017

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Polish scientists have measured the activities of four enzymes in the brain implicated in the mechanism of morphine addiction in the search for therapeutic targets which do not produce the serious side effects during pain treatment.

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Education

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Selected key technologies of the analytical science industry are discussed by Steve Down with reference to burgeoning application areas and the scope for future improvements.

Ion source pressure plays a significant role in the process of ionization and the subsequent ion transmission inside a mass spectrometer. Pressurizing the ion source to a gas pressure greater than atmospheric pressure is a relatively new approach that aims to further improve the performance of atmospheric pressure ionization sources. A brief review on the development of super-atmospheric pressure ion sources, including high-pressure electrospray, field desorption and superheated ESI, and the strategies to...

In the current context of international conflicts and localized terrorist actions, there is unfortunately a permanent threat of attacks with unconventional warfare agents. Among these, biological agents such as toxins, microorganisms, and viruses deserve particular attention owing to their ease of production and dissemination. Mass spectrometry-based techniques for the detection and quantification of biological agents have a decisive role to play for countermeasures in a scenario of biological attacks.

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Radiation and Health is a specialty section of Frontiers in Public Health.

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Waters Empower Cloud

Date: Mar 8, 2017

Thomas Tucker from Waters Corporation discusses Empower Cloud, a cloud deployable, compliance ready enterprise Chromatography Data Software (CDS).

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