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Developments in Analysis of Drugs and Metabolites in Skeletal Remains

Bone remains are one of the least characterized and most challenging matrices for forensic toxicological analysis. Before the forensic utility of the matrix may be fully realized, controlled experiments must be carried out. This presentation will highlight the value that UPLC-based approaches have brought to the drug analysis of bone samples. In addition, we will discuss the most recent findings in analytical developments using UPLC-QTof mass spectrometry, including: dramatic enhancements in sensitivity,...

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JMS Special Feature Collections

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For over 20 years, each issue of the Journal of Mass Spectrometry has contained a Special Feature article. These are highly regarded in the mass spectrometry community and extremely popular with researchers around the globe. These features are freely available to the entire mass spec community.

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An overview is presented of studies on colorectal cancer published in the last 5 years that led to the identification of protein biomarkers suitable for clinical application using proteomic approaches.

The technical aspects of high-resolution MRI of the knee are discussed and the diagnostic criteria for detecting meniscal and cruciate tears with MRI is reviewed, including an update on knee MRI pertaining to advanced imaging.

Scientists in China have identified a range of potential biomarkers of Alzheimer's disease from a metabolomics and proteomics study of the rat model, providing insight into diagnosis of the condition and candidates for therapeutic targets.

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Selected key technologies of the analytical science industry are discussed by Steve Down with reference to burgeoning application areas and the scope for future improvements.

Ion source pressure plays a significant role in the process of ionization and the subsequent ion transmission inside a mass spectrometer. Pressurizing the ion source to a gas pressure greater than atmospheric pressure is a relatively new approach that aims to further improve the performance of atmospheric pressure ionization sources. A brief review on the development of super-atmospheric pressure ion sources, including high-pressure electrospray, field desorption and superheated ESI, and the strategies to...

In the current context of international conflicts and localized terrorist actions, there is unfortunately a permanent threat of attacks with unconventional warfare agents. Among these, biological agents such as toxins, microorganisms, and viruses deserve particular attention owing to their ease of production and dissemination. Mass spectrometry-based techniques for the detection and quantification of biological agents have a decisive role to play for countermeasures in a scenario of biological attacks.

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Radiation and Health is a specialty section of Frontiers in Public Health.

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Waters Empower Cloud

Date: Mar 8, 2017

Thomas Tucker from Waters Corporation discusses Empower Cloud, a cloud deployable, compliance ready enterprise Chromatography Data Software (CDS).

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