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Developments in Analysis of Drugs and Metabolites in Skeletal Remains

Bone remains are one of the least characterized and most challenging matrices for forensic toxicological analysis. Before the forensic utility of the matrix may be fully realized, controlled experiments must be carried out. This presentation will highlight the value that UPLC-based approaches have brought to the drug analysis of bone samples. In addition, we will discuss the most recent findings in analytical developments using UPLC-QTof mass spectrometry, including: dramatic enhancements in sensitivity,...

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thumbnail image: <font size=3>Wiley Registry 11th Edition/NIST 2017 Mass Spectral Library</font>

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Nuclear magnetic resonance (NMR) spectroscopy could help solve a commonly intractable medical problem: how to determine the aggressiveness of prostate cancer. The new approach could help oncologists identify which tumours could be life threatening and need radical treatment

Intact, highly‐charged protein ions have been formed on high vacuum TOF mass spectrometers in linear and reflectron modes by effective matrix removal from sample surfaces and charged clusters, suggesting mechanistic links to traditional ionization methods of electrospray ionization and matrix‐assisted laser desorption/ionization.

The electronic spectra of Nd2+ ions in bromide and iodide hosts have been measured for the first time and the effects of the halide ions have been simulated successfully.

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This glossary of chemometrics terms is provided with the permission of Bryan Prazen of the Synovec Group, Department of Chemistry, University of Washington.

Written specially for spectroscopyNOW.com by Prof Javier Laserna at the University of Málaga.

Professor Tony Mallet of the University of Greenwich presents an essay on elemental compositions from 'accurate mass' determinations.

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X-Ray Spectrometry is devoted to the rapid publication of papers dealing with the theory and application of x-ray spectrometry using electron, x-ray photon, proton, γ and γ-x sources.

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