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Peptide Hormones in Sports Drug Testing: Detection of Emerging Protein/Peptide Based Drugs by Means of LC-MS

Therapeutic proteins and peptides have emerged as one of the most important classes of new pharmaceuticals. Several drug candidates with potential performance-enhancing properties are currently in preclinical or clinical development. The current version of the WADA Prohibited List includes a variety of protein/peptide-based doping agents, some of which can be detected in biological samples by using immunological and mass spectrometry-based approaches.

Read More thumbnail image: <font color=red>Webinar<br/>Now available on-demand</font><br/>Peptide Hormones in Sports Drug Testing: Detection of Emerging Protein/Peptide Based Drugs by Means of LC-MS

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Wiley Spectra Lab:
The World's Largest Spectral Database

thumbnail image: <font size=3>Wiley Spectra Lab:</font><br/>The World's Largest Spectral Database

Wiley Spectra Lab is an expert spectral data system that uses empirical spectral data and advanced software to help chemists, toxicologists, and life scientists confidently identify chemical substances. Powered by the KnowItAll® analytical platform by Bio-Rad, Wiley Spectra Lab provides researchers with access to 2.2 million MS, NMR, and IR spectra – the broadest and largest collection in the world.

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Cool microscopy: Nobel chemistry

David Bradley

Oct 15, 2017

thumbnail image: Cool microscopy Nobel chemistry

The development of cryo-electron microscopy has led to this year's Nobel Prize for Chemistry been awarded to Jacques Dubochet of the University of Lausanne, Switzerland, Joachim Frank of Columbia University, New York, USA, and Richard Henderson of the Medical research Council Laboratory of Molecular Biology (MRC-LMB) in Cambridge, UK.

Various techniques including graphite furnace atomic absorption spectrometry have been used to assess the bioavailability of metals ions present in beef, pork, and chicken after thermal treatment. The study shows that high temperatures make nutrient metal ions of calcium, copper, iron, magnesium and zinc less readily available.

A powerful new NMR technique DiffErential EPitope mapping by STD NMR spectroscopy (DEEP-STD NMR) is being used by researchers in the UK to reveal the nature of the contact between ligand and protein target with a view to developing new pharmaceuticals with fewer side-effects.

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This glossary of chemometrics terms is provided with the permission of Bryan Prazen of the Synovec Group, Department of Chemistry, University of Washington.

Written specially for by Prof Javier Laserna at the University of Málaga.

Professor Tony Mallet of the University of Greenwich presents an essay on elemental compositions from 'accurate mass' determinations.

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X-Ray Spectrometry is devoted to the rapid publication of papers dealing with the theory and application of x-ray spectrometry using electron, x-ray photon, proton, γ and γ-x sources.

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The application of ICP-MS for the characterization of single nanoparticles in biological and environmental water samples

Date: Nov 14, 2017 - 15:00

The rapidly growing use of engineered nanomaterials in many environmentally relevant applications requires novel analytical approaches for determining their presence and concentrations in water and other environmental matrices. To date there are no standard methods for monitoring this emerging class of materials. Advances in ICP-MS software and hardware, available in the Agilent 7900, allow the detection of single nanoparticles in these environmental matrices. The webinar will present an application of...

thumbnail image: The application of ICP-MS for the characterization of single nanoparticles in biological and environmental water samples
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Agilent CTO elected to NAE

Feb 28, 2017

Darlene Solomon, Agilent Technologies’ senior vice president and chief technology officer, has been elected to the US National Academy of Engineering (NAE).

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New Thermo Fisher Products at Pittcon 2017

Date: Mar 8, 2017

Scot Ellis, Marketing Manager, Molecular Spectroscopy at Thermo Fisher discusses the new Raman iXR spectrometer and the Nicolet iN 5 FTIR microscope.

thumbnail image: New Thermo Fisher Products at Pittcon 2017
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