Special issue on mass spectrometry imaging

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  • Published: Mar 18, 2015
  • Author: Steve Down
  • Channels: X-ray Spectrometry / Atomic / Chemometrics & Informatics / UV/Vis Spectroscopy / NMR Knowledge Base / MRI Spectroscopy / Infrared Spectroscopy / Base Peak / Raman / Proteomics

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A journal issue devoted to mass spectrometry imaging has been published by Analytical and Bioanalytical Chemistry with a number of contributions from different research organisations.

One of the key papers lays out the a procedure for submitting MSI data to the ProteomeXchange using the PRIDE database, an essential step in establishing a public repository. It "allows public dissemination of MS imaging data based on existing public investment and infrastructure, avoiding significant extra costs for the development of a new, dedicated resource," say the research team.

Other important submissions amongst the 31 papers in this issue include:

  • Reporting guidelines for mass spectrometry imaging
  • Optimisation of colour schemes to accurately display mass spectrometry imaging data based on human colour perception
  • A micropixelated ion-imaging detector for mass resolution enhancement of a QMS instrumen
  • Three-dimensional imaging of lipids and metabolites in tissues by nanospray desorption electrospray ionization mass spectrometry
  • An enhanced droplet-based liquid microjunction surface sampling system coupled with HPLC-ESI-MS/MS for spatially resolved analysis
  • Lateral resolution in NALDI MSI: back to the future
  • Towards imaging metabolic pathways in tissues
  • The challenge of on-tissue digestion for MALDI MSI— a comparison of different protocols to improve imaging experiments
  • Distributed computing strategies for processing of FT-ICR MS imaging datasets for continuous mode data visualization

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