Structure-Based Drug Design

The 13th Structure-Based Drug Discovery conference will feature the development of in silico technology as well as experimental approaches useful for accurately predicting and modeling the structures of proteins in structure-based drug design efforts. In addition, examples of successful applications of such technology approaches to genome-to-drug lead investigations are showcased.

Topics to be covered may include:

• Recent research on important targets that are amenable to structure-based drug design, such as GPCRs
• Design of therapeutic agents that interact with protein-protein interactions hot spots as targets
• Large-scale informatics framework that integrate functional, structural and expression information for contextual drug discovery
• Mining the bacterial genome for novel bioactive compounds
• Epigenetics in drug discovery
• Cellular environment including solvation in drug discovery
• Fragment-based design
• Other interesting topics