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Journal Highlight: Advantages and limitations of X-ray and computed tomography systems for the study of the skeleton in meagre (Argyrosomus regius)

Date: Jun 11, 2012

Author: spectroscopyNOW

The skeleton of a meagre (Argyrosomus regius) was examined by means of standard X-rays and computerized X-ray tomography and both imaging methods were compared.

Read More thumbnail image: Journal Highlight Advantages and limitations of X-ray and computed tomography systems for the study of the skeleton in meagre Argyrosomus regius

Focus on X-rays: No more data sacrifice

Date: Jun 1, 2012

Author: David Bradley

The equivalent of a new pair of spectacles has come in the form of an advanced method for analysing the so-called "discarded" X-ray data from a crystallographic study. The analytical technique could help improve structural studies on biopolymers including proteins and nucleic acids.

Read More thumbnail image: Focus on X-rays No more data sacrifice

X-ray solution to obesity: Structural target revealed

Date: May 15, 2012

Author: David Bradley

Researchers at the University of Sheffield, UK, have used X-ray crystallography to obtain a detailed structure of a key component of the human obesity receptor, the binding domain for the satiety hormone leptin.

Read More thumbnail image: X-ray solution to obesity Structural target revealed

Journal Highlight: Chemical analysis of very small-sized samples by wavelength-dispersive X-ray fluorescence

Date: May 7, 2012

Author:

A set of methods was developed for the chemical characterisation of very small-sized samples by wavelength-dispersive X-ray fluorescence and validated using reference materials.

Read More thumbnail image: Journal Highlight Chemical analysis of very small-sized samples by wavelength-dispersive X-ray fluorescence

Protein breakdown: X-ray clues in disease

Date: Apr 15, 2012

Author: David Bradley

X-ray crystallography has been used to investigate the protein machinery that medical researchers say goes awry in uncontrolled or inaccurate degradation of cellular proteins. The research offers new clues on how cancer or Alzheimer's disease might develop.

Read More thumbnail image: Protein breakdown X-ray clues in disease

Journal Highlight: A miniature X-ray emission spectrometer (miniXES) for high-pressure studies in a diamond anvil cell

Date: Apr 9, 2012

Author:

A miniature X-ray emission spectrometer based on a coarsely diced approximant of the Johansson optic has been developed to study volume collapse in Pr metal and compounds.

Read More thumbnail image: Journal Highlight A miniature X-ray emission spectrometer miniXES for high-pressure studies in a diamond anvil cell

Complex answer: Finding hepatitis C antivirals

Date: Apr 1, 2012

Author: David Bradley

Hepatitis C is a chronic infectious disease that afflicts some 170 million people worldwide, causing chronic liver disease and liver cancer. Chemists at the University of California, San Diego have finally obtained the first high- resolution crystal structure of a compound that binds to the genetic material of the hepatitis C virus and blocks its replication.

Read More thumbnail image: Complex answer Finding hepatitis C antivirals

Resisting resistance: Exposing sulfa drug mechanism

Date: Mar 15, 2012

Author: David Bradley

X-ray diffraction has been used to pin down the mode of action of the sulfa antibiotics, which were first used 70 years ago. The work could provide clues to developing a new generation of antibiotics that would have fewer side effects and could stave off bacterial drug resistance at least temporarily.

Read More thumbnail image: Resisting resistance Exposing sulfa drug mechanism

Journal Highlight: PIXE-RBS survey of a Meissen porcelain snuff box: first version or not?

Date: Mar 12, 2012

Author:

The combination of proton-induced X-ray emission and Rutherford backscattering spectrometry was used to make both bulk composition and surface characterization data simultaneously available, to study the provenance of a Meissen snuff box.

Read More thumbnail image: Journal Highlight PIXE-RBS survey of a Meissen porcelain snuff box first version or not

Drugs enmeshed: Superhydrophobic slow delivery

Date: Feb 15, 2012

Author: David Bradley

X-ray computed tomography can be used to look closely at superhydrophobic polymer meshes. These experimental materials have been shown to trap drug molecules with a barrier of air between them and an external aqueous environment.

Read More thumbnail image: Drugs enmeshed Superhydrophobic slow delivery
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