Thermo Fisher unveils new bioprocessing products

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  • Published: Apr 27, 2016
  • Author: Jon Evans
  • Source: Thermo Fisher Scientific
  • Suppliers: Thermo Fisher Scientific
  • Channels: Gas Chromatography / Ion Chromatography / HPLC / Laboratory Informatics / Electrophoresis / Sample Preparation / Detectors / Proteomics & Genomics / Raman / NMR Knowledge Base / X-ray Spectrometry / Atomic / Infrared Spectroscopy / Proteomics / Base Peak / UV/Vis Spectroscopy / Chemometrics & Informatics / MRI Spectroscopy

Thermo Fisher Scientific highlighted a range of new products for bioprocessing applications at the recent International Pharmaceutical Expo in New York, including innovations in single-use technologies, cell culture, protein purification and mass spectrometry.

“Emerging markets for precision medicine, continued growth for biotherapeutics and a renewed focus on cost, increase pressure on customers to identify efficiencies in their production processes,” said Cory Stevenson, president of Thermo Fisher’s bioproduction business. “Our emphasis on best-in-class products across the workflow helps our customers to accelerate innovation and increase productivity.”

  • Thermo Fisher has developed a comprehensive protein analytics platform to support microbial and process quality when accuracy and time-to-results are critical. The Applied Biosystems ProteinSEQ Protein Quantitation System, a breakthrough immuno-PCR platform for residual host-cell protein (HCP) and protein A quantitation, is designed for sensitive and robust protein quantitation with dynamic range. It provides greater confidence and quality of data throughout the production process.
  • Glycosylation is one of the key critical quality attributes of monoclonal antibody-based biotherapeutics, affecting a biological drug’s safety, efficacy, clearance and immunogenicity. The new Applied Biosystems GlycanAssure Glycan Analysis and Quantitation System is the first solution to combine high-throughput and high-data quality in an integrated platform. This helps save labor, time and analysis costs by using simple sample preparation, a multi-capillary electrophoresis instrument and assay-specific software.
  • To enhance productivity while improving protein quality, Thermo Fisher has introduced Gibco GlycanTune, a feeding supplement engineered to provide precision and control in predictively shifting glycan profiles. Based on EfficientFeed technology, the feed also produces a multi-fold increase in titers and maximizes bioreactor utilization.
  • Thermo Fisher’s single-use technologies comprise best-in-class bioreactors, mixers, fermentors and ancillary products that enhance efficiency, speed and reproducible results. At the core are both standard and custom-built BioProcess Containers, which are specially engineered films configured to fit customers’ unique applications and provide process flexibility.
  • To address downstream purification challenges, new Thermo Scientific POROS CaptureSelect AAV8 and POROS CaptureSelect AAV9 Affinity Resins are engineered to address the high selectivity and capacity requirements needed for the purification of adeno-associated virus types 8 and 9, which are often used for gene therapy applications.
  • Thermo Scientific POROS MabCapture A Select Resin combines high-throughput purification performance at a lower price to reduce the cost of pre-clinical development and process-scale manufacturing.
  • Regulatory changes and increased competition from biosimilar products continue to pressure biotherapeutic drug manufacturers to streamline their analytical processes. The recently launched Thermo Scientific Vanquish Flex system is a UHPLC instrument with a fully biocompatible flow path, sample pre-compression and a broad range of detectors to suit biotherapeutic analysis from intact proteins to unlabeled free glycans.

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