Agilent presents Thought Leader Award for protein characterization

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  • Published: Apr 27, 2018
  • Source: Agilent Technologies
  • Suppliers: Agilent Technologies
  • Channels: HPLC / Sample Preparation / Base Peak

Agilent Technologies has announced that two leading scientists at the University of Michigan (UM), US – Brandon Ruotolo and Kristina Hakansson – have received an Agilent Thought Leader Award in support of their research into understanding the structure and function of proteins and protein complexes via mass spectrometry. Ruotolo is a professor of analytical chemistry and chemical biology, whike Hakansson is a professor of chemistry.

A primary focus of their work is the development of techniques for more rapid and specific characterization of intact proteins and protein complexes. These techniques include various modes of chemical modification, new fragmentation approaches and ion mobility mass spectrometry, which can determine the composition, size and topological organization of protein assemblies from a small amount of sample.

The award provides three years of financial assistance, along with Agilent instrumentation for ion mobility mass spectrometry, high-performance liquid chromatography, and sample preparation and introduction. Additionally, on-going collaboration and support from Agilent experts is offered to accelerate the research.

“Partnering with leading researchers in mass spectrometry-based protein characterization will enable Agilent to more rapidly evaluate and commercialize new bioanalytical technologies and solutions,” said Monty Benefiel, vice president and general manager of Agilent's Mass Spectrometry Division. “Together, we will advance understanding, technologies, techniques and solutions in this dynamic space.”

“I'm both humbled and honored by this award from Agilent Technologies,” said Ruotolo. “Furthermore, I am excited to deepen our collaborative relationship, as well as with the Hakansson lab. My hope is that Agilent's generosity today precipitates a long-term partnership between UM and Agilent in the area of chemical measurement science, allowing us to push forward and develop exciting new technologies that represent the forefront of this area together.”

“I'm thrilled to receive this opportunity to further push our electron-based structural characterization methods on a new instrument platform and to formalize our existing collaboration with the Ruotolo laboratory,” said Hakansson. “We have complementary expertise in areas of interest to Agilent, and there is great synergy between our research groups – it will be very exciting to continue in this direction.”

Ruotolo and Hakansson will be collaborating with several biopharmaceutical industry scientists to help ensure their research targets current protein characterization challenges of high importance, and to provide opportunities for evaluation and optimization of new approaches.

The Agilent Thought Leader Award promotes fundamental scientific advances by contributing financial support, products and expertise to the research of influential thought leaders in life sciences, diagnostics and chemical analysis.


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