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Prebiotic depsipeptides: Triboelectric nanogeneration for MS detection

Date: Jul 12, 2019

Author: Steve Down

Hundreds of depsipeptides prepared from a simulated prebiotic mixture of eleven amino acids and three α-hydroxy acids have been characterised by ultrahigh resolution mass spectrometry involving ionisation with a triboelectric nanogenerator.

Read More thumbnail image: Prebiotic depsipeptides Triboelectric nanogeneration for MS detection

Journal Highlight: Comparison of quantitative PCR and MALDI‐TOF mass spectrometry assays for identification of bacteria in milk samples from cows with subclinical mastitis

Date: Jul 9, 2019

Author: spectroscopyNOW

A qualitative and quantitative comparison of bacterial identification in milk samples from cows with subclinical mastitis using a multiplex qPCR assay and MALDI‐TOF MS highlighted the limitations and complementarity of the genetic and phenotypic tests.

Read More thumbnail image: Journal Highlight Comparison of quantitative PCR and MALDITOF mass spectrometry assays for identification of bacteria in milk samples from cows with subclinical mastitis

Fish authentication: Skin proteins by MALDI mass spectrometry

Date: Jun 28, 2019

Author: Steve Down

Fish species have been authenticated by analysing the protein profiles of their skin by MALDI TOFMS, backed up by chemometric analysis, creating a powerful weapon against food fraud, health risks and the protection of threatened species.

Read More thumbnail image: Fish authentication Skin proteins by MALDI mass spectrometry

Nail bar technicians: Exposure to volatile chemicals

Date: Jun 13, 2019

Author: Steve Down

A GC/MS study of nail bars in Boston, MA has shown that the nail technicians are exposed to several volatile organic compounds, some of which enter their bloodstream with the potential to cause harmful health effects.

Read More thumbnail image: Nail bar technicians Exposure to volatile chemicals

Journal Highlight: Mass spectral databases for metabolomics: How to build a consistently annotated mass spectral database from pure reference compounds analyzed under electrospray ionization conditions?

Date: Jun 13, 2019

Author: spectroscopyNOW

New guidelines have been proposed for harmonized nomenclature of ions generated under electrospray conditions, to annotate high resolution mass spectra obtained from standard compounds to set up mass spectral databases.

Read More thumbnail image: Journal Highlight Mass spectral databases for metabolomics How to build a consistently annotated mass spectral database from pure reference compounds analyzed under electrospray ionization conditions

Toxic phorbol esters in medical products: Ambient mass spectrometry for mobile testing

Date: May 22, 2019

Author: Steve Down

Toxic phorbol esters have been measured in glycerol-based products derived from the Jatropha curcas plant using the ambient paper spray ionisation technique coupled with a portable mass spectrometer, providing a method for onsite analysis.

Read More thumbnail image: Toxic phorbol esters in medical products Ambient mass spectrometry for mobile testing

Cocaine testing in wastewater: Mixed-mode chromatography in LC/MS

Date: May 9, 2019

Author: Steve Down

Mixed-mode chromatography combined with tandem mass spectrometry has been used for the first time to measure cocaine and its metabolites and pyrolytic products in wastewater, illustrated by the analysis of samples from Spain and Brazil.

Read More thumbnail image: Cocaine testing in wastewater Mixed-mode chromatography in LCMS

Journal Highlight: Mass spectrometric study of acoustically levitated droplet illuminates molecular‐level mechanism of photodynamic therapy for cancer involving lipid oxidation

Date: May 9, 2019

Author: spectroscopyNOW

Field‐induced droplet ionization mass spectrometry combined with acoustic levitation has been used to study the wall‐less oxidation reactions of 18:1 cardiolipin and POPG mediated by singlet oxygen at the air‐water interface of levitated water droplets.

Read More thumbnail image: Journal Highlight Mass spectrometric study of acoustically levitated droplet illuminates molecularlevel mechanism of photodynamic therapy for cancer involving lipid oxidation

Grenfell's toxic legacy: Deadly dioxins in local soil and dust

Date: Apr 25, 2019

Author: Steve Down

Elevated levels of toxic compounds such as dioxins, PAHs and hydrogen cyanide have been found in soil and an apartment near the site of the Grenfell Tower fire of 2017, posing serious health risks to local people and survivors.

Read More thumbnail image: Grenfells toxic legacy Deadly dioxins in local soil and dust

Parkinson's perfume: Sebum biomarkers form diagnostic panel

Date: Apr 10, 2019

Author: Steve Down

The characteristic odour that escapes from the skin of people with Parkinson's disease that could be detected by an especially sensitive individual has now been characterised by scientists in the UK, leading to the possibility of a skin swab test for early detection of the disease.

Read More thumbnail image: Parkinsons perfume Sebum biomarkers form diagnostic panel
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