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Webinar Review: New Technologies to Streamline Chemical Imaging and Quantification of Active Pharmaceutical Ingredient (API) Forms in Drug Development

This webinar describes the application and advantages of Raman and IR Spectroscopy for the analysis of oral solid dose pharmaceutical drugs.

Read More thumbnail image: Webinar Review: New Technologies to Streamline Chemical Imaging and Quantification of Active Pharmaceutical Ingredient (API) Forms in Drug Development

Webinar
Now available on-demand
New Technologies to Streamline Chemical Imaging and Quantification of API Forms in Drug Development

This webinar will describe the use of molecular spectroscopy techniques (Raman and IR) for solid-state analysis in drug development. Two presentations will focus on chemical imaging of polymorphs by LDIR, and the rapid quantification of low level crystalline forms using transmission Raman.

Read More thumbnail image: <font color=red>Webinar<br/>Now available on-demand<br/></font>New Technologies to Streamline Chemical Imaging and Quantification of API Forms in Drug Development

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UV-1900
Advantages of Low Stray Light

thumbnail image: <font size=3>UV-1900</font><br />Advantages of Low Stray Light

It is known that the concentration of a solution can be determined easily and precisely by a UV-Vis spectrophotometer. Recent demands for quantitative measurement by UV-Vis spectroscopy are the quantitation of a component with low concentration and the quantitation of a solution with high concentration without dilution. Here, the quantitation limit and the linearity of a calibration curve for aqueous solutions of caffeine and acetic acid are obtained by using the UV-1900 as demonstrated.

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Ezines

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An in‐line flow cell has been designed for downstream chromatographic processing with Raman spectroscopic detection, backed up by chemometric modelling and illustrated by the prediction of monoclonal antibody concentrations in harvests with a high content of impurities.

Per- and poly-fluoroalkyl compounds have been found in a wide range of environments. Now, measured data on mobility in different types of soil have been used to model the transport of the important contaminant perfluorooctanoic acid (PFOA).

Live view: NMR in a eukaryotic cell

David Bradley

Jun 15, 2019

thumbnail image: Live view NMR in a eukaryotic cell

The three-dimensional structure of a protein within a living higher eukaryotic cell can be obtained using nuclear magnetic resonance (NMR) spectroscopy and computational methods, according to research from Tokyo published in Angewandte Chemie.

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Education

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For over 20 years, each issue of the Journal of Mass Spectrometry has contained a Special Feature article. These are highly regarded in the mass spectrometry community and extremely popular with researchers around the globe. These features are freely available to the entire mass spec community.

Selected key technologies of the analytical science industry are discussed by Steve Down with reference to burgeoning application areas and the scope for future improvements.

Ion source pressure plays a significant role in the process of ionization and the subsequent ion transmission inside a mass spectrometer. Pressurizing the ion source to a gas pressure greater than atmospheric pressure is a relatively new approach that aims to further improve the performance of atmospheric pressure ionization sources. A brief review on the development of super-atmospheric pressure ion sources, including high-pressure electrospray, field desorption and superheated ESI, and the strategies to...

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Radiation and Health is a specialty section of Frontiers in Public Health.

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